Mir1188 (microRNA 1188) - Rat Genome Database
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Gene: Mir1188 (microRNA 1188) Mus musculus
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Symbol: Mir1188
Name: microRNA 1188
RGD ID: 4804529
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-1188; Mirn1; Mirn1188; mmu-mir-1188
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912109,578,256 - 109,578,375 (+)NCBIGRCm39mm39
GRCm3812109,611,822 - 109,611,941 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12109,611,822 - 109,611,941 (+)EnsemblGRCm38mm10GRCm38
Celera12110,806,565 - 110,806,684 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16381832   PMID:17989215   PMID:20215419   PMID:20413612   PMID:21037258   PMID:25694452  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142002Tbqt3_mtibia bone quality traits 3 (mouse)Not determined1235235497109969809Mouse
27226793Feml10_mfemur length 10, 5 week (mouse)1268300000113400000Mouse
13524842Ppiq10a_mprepulse inhibition QTL 10a (mouse)1277545446111545446Mouse
4142401Egq10_mearly growth QTL 10 (mouse)Not determined80909934113419913Mouse
4141335W6q10_mweight 6 weeks QTL 10 (mouse)Not determined80909934113419913Mouse
4141610Tailaq1_mtail length adjusted QTL 1 (mouse)Not determined80909934113419913Mouse
1357701Lvrq10_mliver weight QTL 10 (mouse)Not determined1280909934113419913Mouse
39128213Lwq23_mliver weight QTL 10 (mouse)1280909934113419913Mouse
13524849Ppiq11a_mprepulse inhibition QTL 11a (mouse)1281022884115022884Mouse
13524846Ppiq11_mprepulse inhibition QTL 11 (mouse)1282700137116700137Mouse
1301879Insq10_minsulin QTL 10 (mouse)Not determined1283565816117565965Mouse
1301492Dbsty3_mdiabesity 3 (mouse)Not determined1283565816117565965Mouse
1300883Ath21_matherosclerosis 21 (mouse)Not determined1285995320119995424Mouse
10412156Nociq3_mnociceptive sensitivity inflammatory QTL 3 (mouse)Not determined1286349301114868033Mouse
4142007Chlq17_mcirculating hormone level QTL 17 (mouse)Not determined1288086615120129022Mouse
1300545Lifespan3_mlife span 3 (mouse)Not determined1288086615120129022Mouse
1301308Prdt4_mprion disease incubation time 4 (mouse)Not determined1288342095120129022Mouse
5491194Mobq3_mmultigenic obesity QTL 3 (mouse)Not determined1289697812120129022Mouse
1301836Heal5_mwound healing/regeneration 5 (mouse)Not determined1289972772120129022Mouse
1301922Bbaa6_mB.burgdorferi-associated arthritis 6 (mouse)Not determined1290342009120129022Mouse
10402491Dipa4_mdrug induced psychomotor activation 4 (mouse)Not determined1291256256120129022Mouse
12910532Nrq10a_mnoise-induced hearing loss resistant QTL 10a (mouse)1292783591120129022Mouse
12910533Nrq10_mnoise-induced hearing loss resistant QTL 10 (mouse)1292783591120129022Mouse
1357463Vtbt14_mvertebral trabecular bone trait 14 (mouse)Not determined1292969663120129022Mouse
1300973Abmm_mantibody mediated myocarditis (mouse)Not determined1293298027120129022Mouse
1302177Dps2_mdelta power in slow-wave sleep 2 (mouse)Not determined1294179630120129022Mouse
1302138Im6_mimmunoregulatory 6 (mouse)Not determined1296896717120129022Mouse
1301269Sluc12_msusceptibility to lung cancer 12 (mouse)Not determined1296896717120129022Mouse
10412075Nils1_mneointima lesion size 1 (mouse)Not determined12102060930120129022Mouse
4141297Plyid_mPolymeric IgA dominance (mouse)Not determined109217459115921502Mouse

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:21965
Count of gene targets:9507
Count of transcripts:15999
Interacting mature miRNAs:mmu-miR-1188-3p, mmu-miR-1188-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000116756
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl12109,611,822 - 109,611,941 (+)Ensembl
RefSeq Acc Id: NR_035419
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912109,578,256 - 109,578,375 (+)NCBI
GRCm3812109,611,822 - 109,611,941 (+)ENTREZGENE
Celera12110,806,565 - 110,806,684 (+)ENTREZGENE
cM Map12 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000080406 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000116756 ENTREZGENE
MGD MGI:3783362 ENTREZGENE
miRBase MI0006290 ENTREZGENE
NCBI Gene 100316669 ENTREZGENE
PhenoGen Mir1188 PhenoGen
RNAcentral URS00005661CD RNACentral
  URS000075A22B RNACentral
  URS000075EA43 RNACentral