Rag1<sup>em1Mcwi</sup> (recombination activating gene 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin) - Rat Genome Database

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Gene: Rag1em1Mcwi (recombination activating gene 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin) Rattus norvegicus
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Symbol: Rag1em1Mcwi
Name: recombination activating gene 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
RGD ID: 4139865
Description: This allele was made by zinc finger nuclease mutagenesis. The resulting mutation is a 13-bp frameshift deletion in exon 1 (del 681-693).
ASSOCIATED WITH decreased B cell number; decreased T cell number; decreased thymus weight; ASSOCIATED WITH Albuminuria; Hypertensive Nephropathy
Type: allele  of Rag1  
Also known as: Rag1em1Mcwi
Is Marker For: Strains:   SS-Rag1em1Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic Map3 RGD


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References


Genomics


Related Rat Strains
The following Strains have been annotated to Rag1em1Mcwi


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Rat Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type
Rag1em1Mcwi-var1 chr3 91212237 91212249 GTCACATTCCTTG - deletion

Additional Information