MIR4257 (microRNA 4257) - Rat Genome Database

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Gene: MIR4257 (microRNA 4257) Homo sapiens
Analyze
Symbol: MIR4257
Name: microRNA 4257
RGD ID: 4108963
HGNC Page HGNC:38312
Description: Located in extracellular vesicle.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381150,551,929 - 150,552,014 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1150,551,929 - 150,552,014 (+)EnsemblGRCh38hg38GRCh38
GRCh371150,524,405 - 150,524,490 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera1123,640,169 - 123,640,254 (+)NCBICelera
Cytogenetic Map1q21.2NCBI
HuRef1121,902,542 - 121,902,627 (+)NCBIHuRef
CHM1_11151,920,186 - 151,920,271 (+)NCBICHM1_1
T2T-CHM13v2.01149,675,956 - 149,676,041 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
Additional References at PubMed
PMID:16381832   PMID:19784364   PMID:28798470   PMID:35790263  


Genomics

Variants

.
Variants in MIR4257
1 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1q21.2(chr1:150214843-150565007)x3 copy number gain See cases [RCV000138735] Chr1:150214843..150565007 [GRCh38]
Chr1:150187139..150537483 [GRCh37]
Chr1:148453763..148804107 [NCBI36]
Chr1:1q21.2		 likely benign
GRCh38/hg38 1q21.2-25.2(chr1:149854269-180267197)x3 copy number gain See cases [RCV000143515] Chr1:149854269..180267197 [GRCh38]
Chr1:149825831..180236332 [GRCh37]
Chr1:148092455..178502955 [NCBI36]
Chr1:1q21.2-25.2		 pathogenic
NM_019032.6(ADAMTSL4):c.-84-213G>A single nucleotide variant not provided [RCV001566069] Chr1:150551992 [GRCh38]
Chr1:150524468 [GRCh37]
Chr1:1q21.2		 likely benign
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:21072
Count of gene targets:8962
Count of transcripts:17041
Interacting mature miRNAs:hsa-miR-4257
Prediction methods:Microtar, Miranda, Pita, Pita,Microtar, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 2 4 3 3 4 4 1 2 11 2
Low 1295 1327 599 273 711 184 2111 905 801 137 733 938 95 840 1342 4
Below cutoff 391 495 245 110 212 68 569 445 305 37 112 110 43 131 392

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000581735
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1150,551,929 - 150,552,014 (+)Ensembl
RefSeq Acc Id: NR_036211
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381150,551,929 - 150,552,014 (+)NCBI
GRCh371150,524,405 - 150,524,490 (+)RGD
Celera1123,640,169 - 123,640,254 (+)RGD
HuRef1121,902,542 - 121,902,627 (+)RGD
CHM1_11151,920,186 - 151,920,271 (+)NCBI
T2T-CHM13v2.01149,675,956 - 149,676,041 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC MIR4257 COSMIC
Ensembl Genes ENSG00000264553 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000581735 ENTREZGENE
GTEx ENSG00000264553 GTEx
HGNC ID HGNC:38312 ENTREZGENE
Human Proteome Map MIR4257 Human Proteome Map
miRBase MI0015856 ENTREZGENE
NCBI Gene 100422997 ENTREZGENE
PharmGKB PA165751778 PharmGKB
RNAcentral URS000075D1D5 RNACentral
  URS000075D6B0 RNACentral