RNF227 (ring finger protein 227) - Rat Genome Database

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Gene: RNF227 (ring finger protein 227) Canis lupus familiaris
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Symbol: RNF227
Name: ring finger protein 227
RGD ID: 40919840
Description: ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN protein ubiquitination (inferred); ASSOCIATED WITH Diamond-Blackfan anemia (ortholog); dyskeratosis congenita (ortholog); Li-Fraumeni syndrome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha532,905,781 - 32,908,292 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,871,607 - 32,874,118 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,871,365 - 32,874,027 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,839,318 - 32,841,829 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,795,353 - 32,797,862 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,974,479 - 32,976,990 (-)NCBIUU_Cfam_GSD_1.0


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RNF227
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha532,905,781 - 32,908,292 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,871,607 - 32,874,118 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,871,365 - 32,874,027 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,839,318 - 32,841,829 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,795,353 - 32,797,862 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,974,479 - 32,976,990 (-)NCBIUU_Cfam_GSD_1.0
RNF227
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,913,324 - 7,916,318 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,913,339 - 7,916,289 (-)EnsemblGRCh38hg38GRCh38
GRCh37177,816,642 - 7,819,636 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,757,365 - 7,760,499 (-)NCBINCBI36Build 36hg18NCBI36
Celera177,844,148 - 7,846,772 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,711,229 - 7,713,853 (-)NCBIHuRef
CHM1_1177,825,419 - 7,828,044 (-)NCBICHM1_1
T2T-CHM13v2.0177,818,732 - 7,821,726 (-)NCBIT2T-CHM13v2.0
Rnf227
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,231,282 - 69,233,467 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,231,287 - 69,233,467 (+)EnsemblGRCm39 Ensembl
GRCm381169,340,796 - 69,342,641 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,340,461 - 69,342,641 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,154,271 - 69,156,149 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,157,012 - 69,158,836 (+)NCBIMGSCv36mm8
Celera1176,294,623 - 76,296,499 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.52NCBI
Rnf227
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,559,862 - 54,561,823 (+)NCBIGRCr8
mRatBN7.21054,061,054 - 54,063,015 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,059,947 - 54,063,010 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,722,733 - 58,723,405 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,211,347 - 58,212,019 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,719,493 - 53,720,165 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,940,533 - 55,941,205 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,940,533 - 55,941,205 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,681,368 - 55,684,924 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,133,424 - 56,134,096 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1053,217,612 - 53,218,284 (+)NCBICelera
Cytogenetic Map10q24NCBI
RNF227
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21915,511,339 - 15,514,943 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11717,476,971 - 17,485,904 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,948,370 - 7,951,882 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,936,179 - 7,937,736 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,936,179 - 7,937,723 (-)Ensemblpanpan1.1panPan2
Rnf227
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,682,460 - 47,683,948 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,156,137 - 1,158,022 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,155,936 - 1,158,022 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF227
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,163,866 - 53,166,440 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,163,996 - 53,166,418 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,524,899 - 55,532,596 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNF227
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,296,538 - 7,304,941 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605914,103,421 - 14,111,224 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


RefSeq Acc Id: ENSCAFT00845047010   ⟹   ENSCAFP00845036889
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl532,871,365 - 32,874,027 (-)Ensembl
RefSeq Acc Id: XM_038475617   ⟹   XP_038331545
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1532,839,318 - 32,841,829 (-)NCBI
RefSeq Acc Id: XM_038515798   ⟹   XP_038371726
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha532,905,781 - 32,908,292 (-)NCBI
RefSeq Acc Id: XM_038536790   ⟹   XP_038392718
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0532,974,479 - 32,976,990 (-)NCBI
RefSeq Acc Id: XM_038600944   ⟹   XP_038456872
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0532,795,353 - 32,797,862 (-)NCBI
RefSeq Acc Id: XM_038665509   ⟹   XP_038521437
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0532,871,607 - 32,874,118 (-)NCBI
RefSeq Acc Id: XP_038331545   ⟸   XM_038475617
RefSeq Acc Id: XP_038456872   ⟸   XM_038600944
RefSeq Acc Id: XP_038521437   ⟸   XM_038665509
- UniProtKB: A0A8C0QQ38 (UniProtKB/TrEMBL),   A0A8I3QBH2 (UniProtKB/TrEMBL),   A0A8C0K363 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038371726   ⟸   XM_038515798
- UniProtKB: A0A8C0QQ38 (UniProtKB/TrEMBL),   A0A8I3QBH2 (UniProtKB/TrEMBL),   A0A8C0K363 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038392718   ⟸   XM_038536790
- UniProtKB: A0A8C0K363 (UniProtKB/TrEMBL),   A0A8C0QQ38 (UniProtKB/TrEMBL),   A0A8I3QBH2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845036889   ⟸   ENSCAFT00845047010
Protein Domains
RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000058217 UniProtKB/TrEMBL
  ENSCAFG00030019701 UniProtKB/TrEMBL
  ENSCAFG00040007426 UniProtKB/TrEMBL
  ENSCAFG00845026680 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000109561.1 UniProtKB/TrEMBL
  ENSCAFT00030036180.1 UniProtKB/TrEMBL
  ENSCAFT00040013794.1 UniProtKB/TrEMBL
  ENSCAFT00845047010 ENTREZGENE
  ENSCAFT00845047010.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro DUF4632 UniProtKB/TrEMBL
  Znf-RING_LisH UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene RNF227 ENTREZGENE
PANTHER RING FINGER PROTEIN 227 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam DUF4632 UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/TrEMBL
PROSITE ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A8C0K363 ENTREZGENE
  A0A8C0QQ38 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QBH2 ENTREZGENE, UniProtKB/TrEMBL