APELA (apelin receptor early endogenous ligand)

Gene: APELA (apelin receptor early endogenous ligand) Chlorocebus sabaeus

Analyze

Symbol:

APELA

Name:

apelin receptor early endogenous ligand

RGD ID:

40898439

Description:

ENCODES a protein that exhibits apelin receptor binding (ortholog); hormone activity (ortholog); INVOLVED IN apelin receptor signaling pathway (ortholog); coronary vasculature development (ortholog); embryonic heart tube development (ortholog); ASSOCIATED WITH pre-eclampsia (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666037	91,103,501 - 91,123,641 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

pre-eclampsia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apelin receptor signaling pathway (ISO)

coronary vasculature development (ISO)

embryonic heart tube development (ISO)

placenta blood vessel development (ISO)

positive regulation of angiogenesis (ISO)

positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis (ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

positive regulation of G protein-coupled receptor internalization (ISO)

positive regulation of heart contraction (ISO)

positive regulation of trophoblast cell migration (ISO)

regulation of blood pressure (ISO)

vasculogenesis (ISO)

Cellular Component

extracellular region (ISO)

extracellular space (ISO)

Molecular Function

apelin receptor binding (ISO)

hormone activity (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

APELA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666037	91,103,501 - 91,123,641 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

APELA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	164,877,178 - 164,899,007 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	164,877,178 - 164,898,965 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	165,798,330 - 165,818,679 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Celera	4	163,130,354 - 163,150,890 (+)	NCBI		Celera
Cytogenetic Map	4	q32.3	NCBI
HuRef	4	161,551,632 - 161,572,198 (+)	NCBI		HuRef
CHM1_1	4	165,774,724 - 165,795,263 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	168,224,846 - 168,246,738 (+)	NCBI		T2T-CHM13v2.0

Apela
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	65,481,069 - 65,489,970 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	65,481,069 - 65,489,988 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	65,028,417 - 65,037,336 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	65,028,417 - 65,037,336 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	67,552,316 - 67,561,235 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
Celera	8	67,592,177 - 67,600,984 (-)	NCBI		Celera
Cytogenetic Map	8	B3.1	NCBI
cM Map	8	32.52	NCBI

Apela
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	29,460,855 - 29,469,962 (+)	NCBI		GRCr8
mRatBN7.2	16	24,694,356 - 24,703,466 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	24,694,324 - 24,703,465 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	28,060,134 - 28,069,234 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	31,494,493 - 31,503,593 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	27,449,627 - 27,458,747 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	26,582,103 - 26,583,828 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Celera	16	24,779,756 - 24,788,926 (+)	NCBI		Celera
Cytogenetic Map	16	p13	NCBI

Apela
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955403	40,257,467 - 40,266,275 (-)	NCBI	ChiLan1.0	ChiLan1.0

APELA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	162,679,066 - 162,699,828 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	163,037,099 - 163,057,904 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	157,125,485 - 157,145,999 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	169,176,909 - 169,197,001 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	169,176,910 - 169,195,553 (+)	Ensembl	panpan1.1		panPan2

APELA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	60,967,944 - 60,990,955 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	61,278,318 - 61,300,216 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	61,830,832 - 61,852,734 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	15	60,994,927 - 61,016,846 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	61,056,116 - 61,078,015 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	61,429,794 - 61,451,703 (+)	NCBI		UU_Cfam_GSD_1.0

Apela
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	17,591,770 - 17,600,620 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936555	969,902 - 978,736 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

APELA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	8	53,703,735 - 53,736,989 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	56,863,643 - 56,896,787 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Apela
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624758	11,944,563 - 11,954,027 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_037988038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_037988038 ⟹ XP_037843966

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666037	91,103,501 - 91,123,641 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_037843966	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_037843966 ⟸ XM_037988038

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	APELA	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI