IZUMO1 (izumo sperm-oocyte fusion 1) - Rat Genome Database

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Gene: IZUMO1 (izumo sperm-oocyte fusion 1) Chlorocebus sabaeus
Analyze
Symbol: IZUMO1
Name: izumo sperm-oocyte fusion 1
RGD ID: 40896528
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN single fertilization (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN acrosomal vesicle (ortholog); endoplasmic reticulum membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: izumo sperm-egg fusion 1; izumo sperm-egg fusion protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366607321,860,467 - 21,867,228 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
IZUMO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366607321,860,467 - 21,867,228 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
IZUMO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,740,852 - 48,746,909 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,740,852 - 48,746,909 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,244,109 - 49,250,166 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361953,935,957 - 53,941,978 (-)NCBINCBI36Build 36hg18NCBI36
Celera1946,110,237 - 46,116,258 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,622,956 - 45,628,979 (-)NCBIHuRef
CHM1_11949,245,907 - 49,251,937 (-)NCBICHM1_1
T2T-CHM13v2.01951,735,271 - 51,741,330 (-)NCBIT2T-CHM13v2.0
Izumo1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,270,251 - 45,276,653 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,271,235 - 45,278,247 (+)EnsemblGRCm39 Ensembl
GRCm38745,621,811 - 45,627,242 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,621,811 - 45,628,823 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,877,181 - 52,882,612 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,489,853 - 45,495,284 (+)NCBIMGSCv36mm8
Celera741,083,355 - 41,088,784 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.39NCBI
Izumo1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,227,603 - 105,233,357 (+)NCBIGRCr8
mRatBN7.2196,090,817 - 96,096,893 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1101,476,573 - 101,482,331 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,949,270 - 109,955,032 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,239,647 - 103,245,402 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,603,222 - 101,608,977 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,603,222 - 101,608,976 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,682,002 - 102,687,757 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,090,118 - 96,095,872 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera190,344,795 - 90,350,549 (+)NCBICelera
Cytogenetic Map1q22NCBI
Izumo1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555591,825,589 - 1,830,535 (+)NCBIChiLan1.0ChiLan1.0
IZUMO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22054,844,051 - 54,850,311 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,770,395 - 56,776,681 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,740,372 - 45,747,177 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,330,542 - 54,337,974 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,330,545 - 54,337,533 (-)Ensemblpanpan1.1panPan2
IZUMO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,579,073 - 107,583,163 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,101,516 - 107,105,593 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,103,745 - 108,107,828 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11107,770,586 - 107,774,666 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,417,509 - 107,421,583 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,253,081 - 108,257,163 (+)NCBIUU_Cfam_GSD_1.0
IZUMO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,072,265 - 54,076,474 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,072,607 - 54,076,319 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,819,983 - 49,824,696 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Izumo1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,173,070 - 5,176,480 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,171,778 - 5,176,674 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007997455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_007997455   ⟹   XP_007995646
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607321,860,467 - 21,867,228 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007995646 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015233
  ENSCSAP00000015233.1
Reference Protein Sequences
RefSeq Acc Id: XP_007995646   ⟸   XM_007997455
- UniProtKB: A0A0D9S2Z4 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002813 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000831.1 UniProtKB/TrEMBL
Gene3D-CATH Immunoglobulins UniProtKB/TrEMBL
InterPro Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  IZUMO UniProtKB/TrEMBL
  Izumo-Ig UniProtKB/TrEMBL
  IZUMO1 UniProtKB/TrEMBL
NCBI Gene IZUMO1 ENTREZGENE
PANTHER IZUMO SPERM-EGG FUSION PROTEIN 1 UniProtKB/TrEMBL
  IZUMO SPERM-EGG FUSION PROTEIN 1 UniProtKB/TrEMBL
Pfam IZUMO UniProtKB/TrEMBL
  Izumo-Ig UniProtKB/TrEMBL
Superfamily-SCOP Immunoglobulin UniProtKB/TrEMBL
UniProt A0A0D9S2Z4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-23 IZUMO1  izumo sperm-oocyte fusion 1  IZUMO1  izumo sperm-egg fusion 1  Symbol and/or name change 5135510 APPROVED