Sfpe1 (sonic hedgehog floor plate enhancer 1) - Rat Genome Database

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Gene: Sfpe1 (sonic hedgehog floor plate enhancer 1) Mus musculus
Analyze
Symbol: Sfpe1
Name: sonic hedgehog floor plate enhancer 1
RGD ID: 39128626
Description: This region contains a brain enhancer of the sonic hedgehog (Shh) gene, located approximately 12 kb downstream. While the entire sequence promotes expression of a reporter gene in the floor plate of the developing nervous system, a subset of this sequence can function as a specific enhancer in the notochord. Function of the notochord element may depend on binding by hepatocyte nuclear factor 3/forkhead family proteins. [provided by RefSeq, Sep 2015]
Type: biological-region
RefSeq Status: REVIEWED
Previously known as: Rr366625; SNE
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39528,681,088 - 28,682,186 (+)NCBIGRCm39GRCm39mm39
GRCm38528,476,090 - 28,477,188 (+)NCBIGRCm38GRCm38mm10GRCm38
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:9847242   PMID:15498458   PMID:16407397   PMID:17157288   PMID:24859115  


Genomics

Variants

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Variants in Sfpe1
57 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12904958Gmmq8_mgastrocnemius muscle mass QTL 8 (mouse)5129421124Mouse
10401122Pgia41_mproteoglycan induced arthritis 41 (mouse)Not determined582314434823280Mouse
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5350482337504823Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5538452039384652Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5812411742124239Mouse
7394748Mom5_mmodifier of Min 5 (mouse)Not determined5884767233475637Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
1357478Kdnw1_mkidney weight 1 (mouse)Not determined5891594940529869Mouse
14696730Kidlq1_mkidney weight, left QTL 1 (mouse)51356315247563152Mouse
1301685Estq2_mestradiol regulated response QTL 2 (mouse)Not determined51563408449634190Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52068699354687134Mouse
1301776Skts3_mskin tumor susceptibility 3 (mouse)Not determined52166729555667403Mouse
11537368Hmtb10_mhemostasis and thrombosis 10 (mouse)52210082354500318Mouse
11537367Hmtb11_mhemostasis and thrombosis 11 (mouse)52210082364806579Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
1300701Cd8ts1_mCD8 T cell subset 1 (mouse)Not determined52721534861215451Mouse


Expression


Sequence



Additional Information

Database Acc Id Source(s)
NCBI Gene Sfpe1 ENTREZGENE
PhenoGen Sfpe1 PhenoGen