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Gene: LOC112694770 (Sharpr-MPRA regulatory region 10281) Homo sapiens
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Symbol: LOC112694770
Name: Sharpr-MPRA regulatory region 10281
RGD ID: 38626506
Description: This genomic sequence was predicted to be a transcriptional regulatory region based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It was validated as a functional enhancer by the Sharpr-MPRA technique (Systematic high-resolution activation and repression profiling with reporter tiling using massively parallel reporter assays) in HepG2 liver carcinoma cells (group: HepG2 Activating DNase matched - State 5:Enh, candidate strong enhancer, open chromatin), with weaker activation in K562 erythroleukemia cells (group: K562 Activating DNase unmatched - State 5:Enh). [provided by RefSeq, Jul 2018]
Type: biological-region
RefSeq Status: REVIEWED
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,888,362 - 23,888,656 (+)NCBIGRCh38GRCh38hg38GRCh38
Cytogenetic Map22qNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
References - uncurated

Genomics


Expression


Sequence

Nucleotide Sequences
Clinical Variants

Additional Information

External Database Links
 
More on LOC112694770
NCBI Gene
Ensembl Gene
JBrowse: hg38
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 38626506
Created: 2020-09-16
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.