Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: LOC111828508 (Sharpr-MPRA regulatory region 1865) Homo sapiens
Symbol: LOC111828508
Name: Sharpr-MPRA regulatory region 1865
RGD ID: 38607627
Description: This genomic sequence was predicted to be a transcriptional regulatory region based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It was validated as a functional enhancer by the Sharpr-MPRA technique (Systematic high-resolution activation and repression profiling with reporter tiling using massively parallel reporter assays) in both HepG2 liver carcinoma cells (group: HepG2 Activating non-DNase unmatched - State 20:ReprD, Polycomb repression with Duke DNase/promoter and conservation enriched) and K562 erythroleukemia cells (group: K562 Activating non-DNase unmatched - State 10:DNaseD, primarily Duke DNase, candidate regulatory elements in more likely repressive locations). [provided by RefSeq, Jan 2018]
Type: biological-region
RefSeq Status: REVIEWED
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382245,969,109 - 45,969,403 (+)NCBIGRCh38GRCh38hg38GRCh38
Cytogenetic Map22qNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
References - uncurated




Nucleotide Sequences
Clinical Variants

Additional Information

External Database Links
More on LOC111828508
Ensembl Gene
JBrowse: hg38
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 38607627
Created: 2020-09-16
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.