Bmpr2<sup>em1Ang</sup> (bone morphogenetic protein receptor type 2; ZFN induced mutant 1, Ang) - Rat Genome Database

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Gene: Bmpr2em1Ang (bone morphogenetic protein receptor type 2; ZFN induced mutant 1, Ang) Rattus norvegicus
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Symbol: Bmpr2em1Ang
Name: bone morphogenetic protein receptor type 2; ZFN induced mutant 1, Ang
RGD ID: 38501087
Description: The mRNA encoding mRNA at 5 ng/μL encoding a pair of zinc-finger nucleases recognizing rat BMPR2 sequences was injected to the cytoplasm of Sprague-Dawley zygotes. A rat line with a heterozygous 140 base pairs deletion in the first exon (BMPR2Δ140Ex1/+ rats) was chosen for this study becauseit displayed an intense pulmonary vascular remodeling at 3 months of life that was absent in the wild-type littermates.
ASSOCIATED WITH vascular smooth muscle hypertrophy; ASSOCIATED WITH Vascular Remodeling
Type: allele  of Bmpr2  
Is Marker For: Strains:   SD-Bmpr2em1Ang+/-  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


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Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References


Genomics


Related Rat Strains
The following Strains have been annotated to Bmpr2em1Ang


Expression


Sequence

Nucleotide Sequences


Additional Information