 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations |
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Analyze GeneStrainQTL List |
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Gene Annotator (Annotation Comparison) |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsDisease AnnotationsGene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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References - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | GOA data from the GO Consortium |
| 3. | MGD data from the GO Consortium |
| 4. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 5. | RGD automated data pipeline |
| 6. | RGD automated import pipeline for gene-chemical interactions |
| 7. | Schaar DG, etal., Brain Res 1996 May 20;721(1-2):217-28. |
| 8. | Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
References - uncuratedGenomics
Comparative Map Data| Stk10 (Rattus norvegicus - Norway rat) |
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| STK10 (Homo sapiens - human) |
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| Stk10 (Mus musculus - house mouse) |
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| Stk10 (Chinchilla lanigera - long-tailed chinchilla) |
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| STK10 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| STK10 (Canis lupus familiaris - dog) |
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| Stk10 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| STK10 (Sus scrofa - pig) |
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| STK10 (Chlorocebus sabaeus - African green monkey) |
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| Stk10 (Heterocephalus glaber - naked mole-rat) |
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Position Markers| D10Got34 |
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| D10Wox27 |
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| AA997828 |
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| RH129287 |
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| AU049011 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 3 | 14 | 6 | 19 | 6 | 7 | 25 | 10 | |||||
| Low | 43 | 43 | 35 | 35 | 8 | 11 | 74 | 28 | 16 | 1 | 8 | ||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_019206 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_008767561 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07029242 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07029243 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07029244 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01063036 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01063037 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01063038 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01063039 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01063040 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01063041 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473948 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| U33472 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000047011 ⟹ ENSRNOP00000044325 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | ENSRNOT00000080404 ⟹ ENSRNOP00000074413 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_019206 ⟹ NP_062079 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
GGTTCCGGCAGCTCCCTGCCGCCACGGGCGCACTCGGCCGGTGCTGCGCTGCGGGGAGGGCGGChide sequence |
| RefSeq Acc Id: | XM_008767561 ⟹ XP_008765783 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
GCCGCGGTTCCGGCAGCTCCCTGCCGCCACGGGCGCACTCGGCCGGTGCTGCGCTGCGGGGAGGhide sequence |
Protein Sequences| Protein RefSeqs | NP_062079 | (Get FASTA) | NCBI Sequence Viewer |
| XP_008765783 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAC52648 | (Get FASTA) | NCBI Sequence Viewer |
| E9PTG8 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM04059 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM04060 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM04061 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM04062 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_062079 ⟸ NM_019206 |
| - UniProtKB: | H9KVF6 (UniProtKB/TrEMBL) |
| - Sequence: |
MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNDVWEILGELGDGAFGKVYKAKNKETGALAAAhide sequence |
| RefSeq Acc Id: | XP_008765783 ⟸ XM_008767561 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNDVWEILGELGDGAFGKVYKAKNKETGALAAAhide sequence |
| RefSeq Acc Id: | ENSRNOP00000074413 ⟸ ENSRNOT00000080404 |
| RefSeq Acc Id: | ENSRNOP00000044325 ⟸ ENSRNOT00000047011 |
Protein Domains
Protein kinase
TranscriptomePromoters| RGD ID: | 13697092 | ||||||||
| Promoter ID: | EPDNEW_R7617 | ||||||||
| Type: | multiple initiation site | ||||||||
| Name: | Stk10_1 | ||||||||
| Description: | serine/threonine kinase 10 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:3779 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000004217 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000044325 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOP00000074413 | UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000047011 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOT00000080404 | UniProtKB/TrEMBL | |
| InterPro | Kinase-like_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| PKK | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Prot_kinase_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Protein_kinase_ATP_BS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Ser/Thr_kinase_AS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| STK10_STKc | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| KEGG Report | rno:29398 | UniProtKB/TrEMBL |
| NCBI Gene | 29398 | ENTREZGENE |
| Pfam | Pkinase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| PKK | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| PhenoGen | Stk10 | PhenoGen |
| PROSITE | PROTEIN_KINASE_ATP | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| PROTEIN_KINASE_DOM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| PROTEIN_KINASE_ST | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| SMART | S_TKc | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| Superfamily-SCOP | SSF56112 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| TIGR | TC217910 | |
| UniGene | Rn.4190 | ENTREZGENE |
| UniProt | A0A0G2K7Z9_RAT | UniProtKB/TrEMBL |
| E9PTG8 | ENTREZGENE | |
| H9KVF6 | ENTREZGENE, UniProtKB/TrEMBL | |
| STK10_RAT | UniProtKB/Swiss-Prot | |
| UniProt Secondary | D3ZUC0 | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2002-06-10 | Stk10 | Serine/threonine kinase 10 | Symbol and Name status set to approved | 70586 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_domains | has potential coiled coil formation domains which encode a highly alpha-helical molecule | 634157 |
| gene_expression | expressed in the olfactory-limbic system of the adult rat brain | 634157 |
| gene_process | helps in the survival of substantia nigra (SN) dopaminergic neurons | 634157 |
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| More on Stk10 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 3779 |
| Created: | 2000-05-25 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-08-20 |
| Status: | ACTIVE |
