ZNF707 (zinc finger protein 707) - Rat Genome Database

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Gene: ZNF707 (zinc finger protein 707) Homo sapiens
Analyze
Symbol: ZNF707
Name: zinc finger protein 707
RGD ID: 36174119
HGNC Page HGNC
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to chromatin; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrolein; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Mouse
Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8143,684,452 - 143,713,898 (+)EnsemblGRCh38hg38GRCh38
GRCh388143,684,479 - 143,695,385 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378144,766,649 - 144,777,555 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map8q24.3NCBI
HuRef8140,019,771 - 140,030,699 (+)NCBIHuRef
CHM1_18144,806,857 - 144,817,741 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15489334   PMID:15489335   PMID:16189514   PMID:16344560   PMID:17207965   PMID:19447967   PMID:21873635   PMID:25416956   PMID:26186194   PMID:26496610  
PMID:27433848   PMID:28514442   PMID:29180619   PMID:31515488   PMID:32296183  


Genomics

Comparative Map Data
ZNF707
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8143,684,452 - 143,713,898 (+)EnsemblGRCh38hg38GRCh38
GRCh388143,684,479 - 143,695,385 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378144,766,649 - 144,777,555 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map8q24.3NCBI
HuRef8140,019,771 - 140,030,699 (+)NCBIHuRef
CHM1_18144,806,857 - 144,817,741 (+)NCBICHM1_1
Zfp707
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391575,840,972 - 75,847,717 (+)NCBIGRCm39mm39
GRCm39 Ensembl1575,840,972 - 75,847,717 (+)Ensembl
GRCm381575,969,123 - 75,975,868 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1575,969,123 - 75,975,868 (+)EnsemblGRCm38mm10GRCm38
MGSCv371575,799,615 - 75,806,295 (+)NCBIGRCm37mm9NCBIm37
MGSCv361575,796,440 - 75,803,120 (+)NCBImm8
Celera1577,470,122 - 77,476,802 (+)NCBICelera
Cytogenetic Map15D3NCBI
Zfp707
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27107,679,597 - 107,686,556 (+)NCBI
Rnor_6.0 Ensembl7117,026,097 - 117,032,863 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07117,025,917 - 117,032,875 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07117,011,970 - 117,018,928 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,996,966 - 114,003,913 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17114,031,086 - 114,037,652 (+)NCBI
Celera7104,036,534 - 104,043,480 (+)NCBICelera
Cytogenetic Map7q34NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001100599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001288805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001288806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001288807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001288808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001288809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_173831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_110190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_110191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_110192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_110193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC105219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK055198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK055263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK095138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW294133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV023324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA007942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA188478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA555314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA917297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA957023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA990503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB099015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB106612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB125792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB249556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: NM_001100598   ⟹   NP_001094068
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001100599   ⟹   NP_001094069
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001288805   ⟹   NP_001275734
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001288806   ⟹   NP_001275735
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001288807   ⟹   NP_001275736
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001288808   ⟹   NP_001275737
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001288809   ⟹   NP_001275738
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
RefSeq Acc Id: NM_173831   ⟹   NP_776192
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
RefSeq Acc Id: NR_110190
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
RefSeq Acc Id: NR_110191
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
RefSeq Acc Id: NR_110192
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
RefSeq Acc Id: NR_110193
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,479 - 143,695,385 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001275734   ⟸   NM_001288805
- Peptide Label: isoform a
- UniProtKB: Q96C28 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001275735   ⟸   NM_001288806
- Peptide Label: isoform a
- UniProtKB: Q96C28 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_776192   ⟸   NM_173831
- Peptide Label: isoform a
- UniProtKB: Q96C28 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001094068   ⟸   NM_001100598
- Peptide Label: isoform a
- UniProtKB: Q96C28 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001275736   ⟸   NM_001288807
- Peptide Label: isoform b
- UniProtKB: Q96C28 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001094069   ⟸   NM_001100599
- Peptide Label: isoform a
- UniProtKB: Q96C28 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001275738   ⟸   NM_001288809
- Peptide Label: isoform c
- UniProtKB: Q96C28 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001275737   ⟸   NM_001288808
- Peptide Label: isoform c
- UniProtKB: Q96C28 (UniProtKB/Swiss-Prot)
- Sequence:
Protein Domains
C2H2-type   KRAB

Promoters
RGD ID:7214379
Promoter ID:EPDNEW_H12935
Type:initiation region
Name:ZNF707_1
Description:zinc finger protein 707
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12936  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388143,684,487 - 143,684,547EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 8q24.3(chr8:141738068-144140607)x1 copy number loss See cases [RCV000140913] Chr8:141738068..144140607 [GRCh38]
Chr8:142764538..145195510 [GRCh37]
Chr8:142823655..145267498 [NCBI36]
Chr8:8q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:208048-145070385)x3 copy number gain See cases [RCV000141808] Chr8:208048..145070385 [GRCh38]
Chr8:158048..146295771 [GRCh37]
Chr8:148048..146266575 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q24.23-24.3(chr8:139188797-146295771)x3 copy number gain not provided [RCV000846814] Chr8:139188797..146295771 [GRCh37]
Chr8:8q24.23-24.3
pathogenic
GRCh37/hg19 8q24.3(chr8:144190206-146295771)x3 copy number gain not provided [RCV000847854] Chr8:144190206..146295771 [GRCh37]
Chr8:8q24.3
uncertain significance
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771)x3 copy number gain not provided [RCV000848478] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:143684819-144287978)x1 copy number loss See cases [RCV000054310] Chr8:143684819..144287978 [GRCh38]
Chr8:144940777..145511679 [GRCh37]
Chr8:144838977..145482487 [NCBI36]
Chr8:8q24.3
pathogenic
GRCh37/hg19 8q24.3(chr8:144775871-144943223)x3 copy number gain not provided [RCV000747964] Chr8:144775871..144943223 [GRCh37]
Chr8:8q24.3
benign
GRCh37/hg19 8p23.1-q24.3(chr8:12490999-146295771)x3 copy number gain See cases [RCV000512169] Chr8:12490999..146295771 [GRCh37]
Chr8:8p23.1-q24.3
pathogenic
GRCh37/hg19 8q24.3(chr8:144725942-145508436)x3 copy number gain See cases [RCV000447256] Chr8:144725942..145508436 [GRCh37]
Chr8:8q24.3
uncertain significance
GRCh37/hg19 8q24.3(chr8:142840194-146280020) copy number gain Intellectual disability [RCV000626547] Chr8:142840194..146280020 [GRCh37]
Chr8:8q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:78614077-145054634)x3 copy number gain See cases [RCV000142597] Chr8:78614077..145054634 [GRCh38]
Chr8:79526312..146280020 [GRCh37]
Chr8:79688867..146250824 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:103306336-145068712)x3 copy number gain See cases [RCV000142810] Chr8:103306336..145068712 [GRCh38]
Chr8:104318564..146294098 [GRCh37]
Chr8:104387740..146264902 [NCBI36]
Chr8:8q22.3-24.3
pathogenic|likely pathogenic
GRCh37/hg19 8q24.3(chr8:143616831-144930611)x1 copy number loss not provided [RCV001006152] Chr8:143616831..144930611 [GRCh37]
Chr8:8q24.3
pathogenic
GRCh37/hg19 8q24.3(chr8:144754114-144857373)x1 copy number loss not provided [RCV001006155] Chr8:144754114..144857373 [GRCh37]
Chr8:8q24.3
likely benign
GRCh38/hg38 8q21.3-24.3(chr8:87931152-145068712)x3 copy number gain See cases [RCV000138551] Chr8:87931152..145068712 [GRCh38]
Chr8:88943380..146294098 [GRCh37]
Chr8:89012496..146264902 [NCBI36]
Chr8:8q21.3-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241605-145054781)x3 copy number gain See cases [RCV000138643] Chr8:241605..145054781 [GRCh38]
Chr8:191605..146280167 [GRCh37]
Chr8:181605..146250971 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:139004218-145049449)x3 copy number gain See cases [RCV000137340] Chr8:139004218..145049449 [GRCh38]
Chr8:140016461..146274835 [GRCh37]
Chr8:140085643..146245639 [NCBI36]
Chr8:8q24.3
likely pathogenic
GRCh38/hg38 8q24.13-24.3(chr8:124498498-145068712)x3 copy number gain See cases [RCV000137346] Chr8:124498498..145068712 [GRCh38]
Chr8:125510739..146294098 [GRCh37]
Chr8:125579920..146264902 [NCBI36]
Chr8:8q24.13-24.3
pathogenic
GRCh37/hg19 8p12-q24.3(chr8:31936551-146295771)x3 copy number gain not provided [RCV000848192] Chr8:31936551..146295771 [GRCh37]
Chr8:8p12-q24.3
pathogenic
GRCh37/hg19 8q24.12-24.3(chr8:122193546-146295771)x3 copy number gain not provided [RCV000849762] Chr8:122193546..146295771 [GRCh37]
Chr8:8q24.12-24.3
pathogenic
GRCh38/hg38 8q24.13-24.3(chr8:124514090-145054634)x3 copy number gain See cases [RCV000053678] Chr8:124514090..145054634 [GRCh38]
Chr8:125526331..146280020 [GRCh37]
Chr8:125595512..146250824 [NCBI36]
Chr8:8q24.13-24.3
pathogenic
GRCh37/hg19 8q24.22-24.3(chr8:134825277-146280828)x3 copy number gain See cases [RCV000448348] Chr8:134825277..146280828 [GRCh37]
Chr8:8q24.22-24.3
pathogenic
GRCh37/hg19 8q23.3-24.3(chr8:114853126-146295771)x3 copy number gain See cases [RCV000512401] Chr8:114853126..146295771 [GRCh37]
Chr8:8q23.3-24.3
pathogenic
GRCh37/hg19 8q24.12-24.3(chr8:121042467-146295771)x3 copy number gain not provided [RCV001006140] Chr8:121042467..146295771 [GRCh37]
Chr8:8q24.12-24.3
pathogenic
GRCh38/hg38 8q21.2-24.3(chr8:85765999-145070385)x3 copy number gain See cases [RCV000143659] Chr8:85765999..145070385 [GRCh38]
Chr8:86778228..146295771 [GRCh37]
Chr8:86863079..146266575 [NCBI36]
Chr8:8q21.2-24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:94682154-145068656)x3 copy number gain See cases [RCV000134353] Chr8:94682154..145068656 [GRCh38]
Chr8:95694382..146294042 [GRCh37]
Chr8:95763558..146264846 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:97382873-145070385)x3 copy number gain See cases [RCV000140447] Chr8:97382873..145070385 [GRCh38]
Chr8:98395101..146295771 [GRCh37]
Chr8:98464277..146266575 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh37/hg19 8q24.22-24.3(chr8:136059859-146295771)x3 copy number gain not provided [RCV000847171] Chr8:136059859..146295771 [GRCh37]
Chr8:8q24.22-24.3
pathogenic
GRCh38/hg38 8q24.21-24.3(chr8:128220912-145049449)x3 copy number gain See cases [RCV000050830] Chr8:128220912..145049449 [GRCh38]
Chr8:129233158..146274835 [GRCh37]
Chr8:129302340..146245639 [NCBI36]
Chr8:8q24.21-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771) copy number gain See cases [RCV000510234] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771)x3 copy number gain See cases [RCV000511095] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:226452-145068712)x3 copy number gain See cases [RCV000142858] Chr8:226452..145068712 [GRCh38]
Chr8:176452..146294098 [GRCh37]
Chr8:166452..146264902 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q24.12-24.3(chr8:121694649-146295771)x3 copy number gain not provided [RCV000683044] Chr8:121694649..146295771 [GRCh37]
Chr8:8q24.12-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:10213-146293414)x3 copy number gain not provided [RCV000747248] Chr8:10213..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:77480050-145068712)x3 copy number gain See cases [RCV000139036] Chr8:77480050..145068712 [GRCh38]
Chr8:78392286..146294098 [GRCh37]
Chr8:78554841..146264902 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:100867343-145070385)x3 copy number gain See cases [RCV000141694] Chr8:100867343..145070385 [GRCh38]
Chr8:101879571..146295771 [GRCh37]
Chr8:101948747..146266575 [NCBI36]
Chr8:8q22.3-24.3
pathogenic
GRCh37/hg19 8q24.21-24.3(chr8:128877995-146295771)x3 copy number gain not provided [RCV001006146] Chr8:128877995..146295771 [GRCh37]
Chr8:8q24.21-24.3
pathogenic
GRCh38/hg38 8p21.3-q24.3(chr8:21291522-145070385)x3 copy number gain See cases [RCV000142021] Chr8:21291522..145070385 [GRCh38]
Chr8:21149033..146295771 [GRCh37]
Chr8:21193313..146266575 [NCBI36]
Chr8:8p21.3-q24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841154-146295771)x3 copy number gain See cases [RCV000511002] Chr8:86841154..146295771 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8q24.22-24.3(chr8:136378789-146295771)x3 copy number gain See cases [RCV000512003] Chr8:136378789..146295771 [GRCh37]
Chr8:8q24.22-24.3
likely pathogenic
GRCh37/hg19 8q24.3(chr8:143815037-146295771)x3 copy number gain not provided [RCV000683020] Chr8:143815037..146295771 [GRCh37]
Chr8:8q24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:142201468-144002730)x1 copy number loss See cases [RCV000135981] Chr8:142201468..144002730 [GRCh38]
Chr8:143282829..145076898 [GRCh37]
Chr8:143280736..145148886 [NCBI36]
Chr8:8q24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:139236824-145068712)x3 copy number gain See cases [RCV000137466] Chr8:139236824..145068712 [GRCh38]
Chr8:140249067..146294098 [GRCh37]
Chr8:140318249..146264902 [NCBI36]
Chr8:8q24.3
likely pathogenic
GRCh38/hg38 8q24.22-24.3(chr8:130639182-145068712)x3 copy number gain See cases [RCV000137644] Chr8:130639182..145068712 [GRCh38]
Chr8:131651428..146294098 [GRCh37]
Chr8:131720610..146264902 [NCBI36]
Chr8:8q24.22-24.3
pathogenic|conflicting data from submitters
GRCh37/hg19 8q24.13-24.3(chr8:125496223-146295771)x3 copy number gain not provided [RCV000845705] Chr8:125496223..146295771 [GRCh37]
Chr8:8q24.13-24.3
pathogenic
GRCh38/hg38 8q23.3-24.3(chr8:113580402-145054634)x3 copy number gain See cases [RCV000050638] Chr8:113580402..145054634 [GRCh38]
Chr8:114592631..146280020 [GRCh37]
Chr8:114661807..146250824 [NCBI36]
Chr8:8q23.3-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000053602] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q22.1-24.3(chr8:98432250-146222672)x4 copy number gain See cases [RCV000448954] Chr8:98432250..146222672 [GRCh37]
Chr8:8q22.1-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:164984-146293414)x3 copy number gain not provided [RCV000747254] Chr8:164984..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q24.3(chr8:142132678-145569441)x1 copy number loss not provided [RCV001006150] Chr8:142132678..145569441 [GRCh37]
Chr8:8q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158991-146280828)x3 copy number gain See cases [RCV000447507] Chr8:158991..146280828 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q24.3(chr8:144771630-144807456)x3 copy number gain not provided [RCV000747963] Chr8:144771630..144807456 [GRCh37]
Chr8:8q24.3
benign
GRCh37/hg19 8q24.3(chr8:144262042-146295771)x3 copy number gain not provided [RCV001259034] Chr8:144262042..146295771 [GRCh37]
Chr8:8q24.3
likely pathogenic

Additional Information

Database Acc Id Source(s)
COSMIC ZNF707 COSMIC
Ensembl Genes ENSG00000181135 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000274352 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000351482 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000393748 UniProtKB/TrEMBL
  ENSP00000413215 UniProtKB/Swiss-Prot
  ENSP00000434215 UniProtKB/TrEMBL
  ENSP00000434322 UniProtKB/TrEMBL
  ENSP00000434503 UniProtKB/TrEMBL
  ENSP00000434791 UniProtKB/TrEMBL
  ENSP00000435251 UniProtKB/TrEMBL
  ENSP00000435679 UniProtKB/TrEMBL
  ENSP00000435906 UniProtKB/TrEMBL
  ENSP00000436212 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000436250 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000436362 UniProtKB/TrEMBL
  ENSP00000436394 UniProtKB/TrEMBL
  ENSP00000436634 UniProtKB/TrEMBL
  ENSP00000437134 UniProtKB/TrEMBL
  ENSP00000481033 UniProtKB/Swiss-Prot
  ENSP00000481069 UniProtKB/Swiss-Prot
  ENSP00000484032 UniProtKB/Swiss-Prot
  ENSP00000484744 UniProtKB/Swiss-Prot
  ENSP00000487682 UniProtKB/TrEMBL
  ENSP00000487846 UniProtKB/TrEMBL
  ENSP00000487900 UniProtKB/TrEMBL
  ENSP00000488006 UniProtKB/TrEMBL
  ENSP00000488098 UniProtKB/TrEMBL
  ENSP00000488157 UniProtKB/TrEMBL
  ENSP00000488184 UniProtKB/TrEMBL
  ENSP00000488529 UniProtKB/TrEMBL
  ENSP00000488596 UniProtKB/TrEMBL
  ENSP00000488654 UniProtKB/TrEMBL
  ENSP00000488675 UniProtKB/TrEMBL
  ENSP00000488790 UniProtKB/TrEMBL
  ENSP00000495224 UniProtKB/TrEMBL
Ensembl Transcript ENST00000358656 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000418203 UniProtKB/Swiss-Prot
  ENST00000442058 UniProtKB/TrEMBL
  ENST00000525185 UniProtKB/TrEMBL
  ENST00000525862 UniProtKB/TrEMBL
  ENST00000526315 UniProtKB/TrEMBL
  ENST00000526970 UniProtKB/TrEMBL
  ENST00000527293 UniProtKB/TrEMBL
  ENST00000527561 UniProtKB/TrEMBL
  ENST00000528456 UniProtKB/TrEMBL
  ENST00000529833 UniProtKB/TrEMBL
  ENST00000530574 UniProtKB/TrEMBL
  ENST00000531985 UniProtKB/TrEMBL
  ENST00000532158 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000532205 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000533031 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000534303 UniProtKB/TrEMBL
  ENST00000611146 UniProtKB/Swiss-Prot
  ENST00000611844 UniProtKB/Swiss-Prot
  ENST00000617261 UniProtKB/Swiss-Prot
  ENST00000622212 UniProtKB/Swiss-Prot
  ENST00000631634 UniProtKB/TrEMBL
  ENST00000631732 UniProtKB/TrEMBL
  ENST00000632754 UniProtKB/TrEMBL
  ENST00000632874 UniProtKB/TrEMBL
  ENST00000632986 UniProtKB/TrEMBL
  ENST00000633041 UniProtKB/TrEMBL
  ENST00000633413 UniProtKB/TrEMBL
  ENST00000633449 UniProtKB/TrEMBL
  ENST00000633543 UniProtKB/TrEMBL
  ENST00000633668 UniProtKB/TrEMBL
  ENST00000633973 UniProtKB/TrEMBL
  ENST00000634047 UniProtKB/TrEMBL
GTEx ENSG00000181135 GTEx
  ENSG00000274352 GTEx
HGNC ID HGNC:27815 ENTREZGENE
Human Proteome Map ZNF707 Human Proteome Map
InterPro KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:286075 UniProtKB/Swiss-Prot
NCBI Gene ZNF707 ENTREZGENE
Pfam KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA142670506 PharmGKB
PROSITE KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8YE36_HUMAN UniProtKB/TrEMBL
  E9PHZ0_HUMAN UniProtKB/TrEMBL
  E9PJ46_HUMAN UniProtKB/TrEMBL
  E9PKX4_HUMAN UniProtKB/TrEMBL
  E9PNV7_HUMAN UniProtKB/TrEMBL
  E9PP66_HUMAN UniProtKB/TrEMBL
  E9PPS7_HUMAN UniProtKB/TrEMBL
  E9PQ20_HUMAN UniProtKB/TrEMBL
  E9PS67_HUMAN UniProtKB/TrEMBL
  Q96C28 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A8K317 UniProtKB/Swiss-Prot
  B3KNY1 UniProtKB/Swiss-Prot
  D3DWK7 UniProtKB/Swiss-Prot