MIR670 (microRNA 670) - Rat Genome Database

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Gene: MIR670 (microRNA 670) Homo sapiens
Analyze
Symbol: MIR670
Name: microRNA 670
RGD ID: 3516312
HGNC Page HGNC
Description: Predicted to act upstream of or within cellular response to leukemia inhibitory factor.
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: hsa-mir-670
RGD Orthologs
Mouse
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1143,559,656 - 43,559,753 (+)EnsemblGRCh38hg38GRCh38
GRCh381143,559,656 - 43,559,753 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371143,581,206 - 43,581,303 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera1143,728,153 - 43,728,250 (+)NCBI
Cytogenetic Map11p11.2NCBI
HuRef1143,291,315 - 43,291,412 (+)NCBIHuRef
CHM1_11143,580,876 - 43,580,973 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References
Additional References at PubMed
PMID:16381832   PMID:16954537   PMID:18215311   PMID:23034410   PMID:25017828   PMID:32572924   PMID:33085761   PMID:34816661  


Genomics

Comparative Map Data
MIR670
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1143,559,656 - 43,559,753 (+)EnsemblGRCh38hg38GRCh38
GRCh381143,559,656 - 43,559,753 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371143,581,206 - 43,581,303 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera1143,728,153 - 43,728,250 (+)NCBI
Cytogenetic Map11p11.2NCBI
HuRef1143,291,315 - 43,291,412 (+)NCBIHuRef
CHM1_11143,580,876 - 43,580,973 (+)NCBICHM1_1
Mir670
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39294,091,645 - 94,091,744 (-)NCBIGRCm39mm39
GRCm39 Ensembl294,091,645 - 94,091,744 (-)Ensembl
GRCm38294,261,300 - 94,261,399 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl294,261,300 - 94,261,399 (-)EnsemblGRCm38mm10GRCm38
MGSCv37294,101,457 - 94,101,556 (-)NCBIGRCm37mm9NCBIm37
Celera295,658,135 - 95,658,234 (-)NCBICelera
Cytogenetic Map2E1NCBI

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:40488
Count of gene targets:14524
Count of transcripts:30313
Interacting mature miRNAs:hsa-miR-670-3p, hsa-miR-670-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system adipose tissue appendage
High
Medium 1 4
Low 3 3 19 2 8 2 11 1 93 4 33 6
Below cutoff 8 5 30 5 6 7 231 1 44 6 3 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_031577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC023085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000390142
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1143,559,656 - 43,559,753 (+)Ensembl
RefSeq Acc Id: NR_031577
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381143,559,656 - 43,559,753 (+)NCBI
GRCh371143,581,206 - 43,581,303 (+)RGD
Celera1143,728,153 - 43,728,250 (+)RGD
HuRef1143,291,315 - 43,291,412 (+)ENTREZGENE
CHM1_11143,580,876 - 43,580,973 (+)NCBI
Sequence:

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11p12-11.2(chr11:40688674-44913409)x3 copy number gain See cases [RCV000133775] Chr11:40688674..44913409 [GRCh38]
Chr11:40710224..44934960 [GRCh37]
Chr11:40666800..44891536 [NCBI36]
Chr11:11p12-11.2
uncertain significance
GRCh38/hg38 11p12-11.2(chr11:41118322-48643003)x1 copy number loss See cases [RCV000135405] Chr11:41118322..48643003 [GRCh38]
Chr11:41139872..48664555 [GRCh37]
Chr11:41096448..48621131 [NCBI36]
Chr11:11p12-11.2
pathogenic
GRCh38/hg38 11p12-11.12(chr11:39179252-49135735)x1 copy number loss See cases [RCV000137391] Chr11:39179252..49135735 [GRCh38]
Chr11:39200802..49157287 [GRCh37]
Chr11:39157378..49113863 [NCBI36]
Chr11:11p12-11.12
pathogenic
GRCh38/hg38 11p12-11.2(chr11:40688674-44184136)x3 copy number gain See cases [RCV000138110] Chr11:40688674..44184136 [GRCh38]
Chr11:40710224..44205686 [GRCh37]
Chr11:40666800..44162262 [NCBI36]
Chr11:11p12-11.2
likely pathogenic
GRCh38/hg38 11p12-11.12(chr11:42727555-49135735)x3 copy number gain See cases [RCV000139422] Chr11:42727555..49135735 [GRCh38]
Chr11:42749105..49157287 [GRCh37]
Chr11:42705681..49113863 [NCBI36]
Chr11:11p12-11.12
likely pathogenic
GRCh38/hg38 11p12-11.2(chr11:42553659-46114792)x1 copy number loss See cases [RCV000142289] Chr11:42553659..46114792 [GRCh38]
Chr11:42575209..46136343 [GRCh37]
Chr11:42531785..46092919 [NCBI36]
Chr11:11p12-11.2
pathogenic
GRCh38/hg38 11p12-11.2(chr11:39684826-44845260)x1 copy number loss See cases [RCV000142439] Chr11:39684826..44845260 [GRCh38]
Chr11:39706376..44866811 [GRCh37]
Chr11:39662952..44823387 [NCBI36]
Chr11:11p12-11.2
pathogenic
GRCh38/hg38 11p13-11.2(chr11:35663578-46959820)x1 copy number loss See cases [RCV000052679] Chr11:35663578..46959820 [GRCh38]
Chr11:35685126..46981371 [GRCh37]
Chr11:35641702..46937947 [NCBI36]
Chr11:11p13-11.2
pathogenic
GRCh38/hg38 11p12-11.2(chr11:36508280-48643003)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052680]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052680]|See cases [RCV000052680] Chr11:36508280..48643003 [GRCh38]
Chr11:36529830..48664555 [GRCh37]
Chr11:36486406..48621131 [NCBI36]
Chr11:11p12-11.2
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:37304 AgrOrtholog
COSMIC MIR670 COSMIC
Ensembl Genes ENSG00000211568 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000390142 ENTREZGENE
GTEx ENSG00000211568 GTEx
HGNC ID HGNC:37304 ENTREZGENE
Human Proteome Map MIR670 Human Proteome Map
miRBase MI0003933 ENTREZGENE
NCBI Gene 100313777 ENTREZGENE
PharmGKB PA165543478 PharmGKB
RNAcentral URS000075B3C7 RNACentral
  URS000075D4D2 RNACentral
  URS000075EF30 RNACentral