RT1-Cl (RT1 class Ib, locus Cl) - Rat Genome Database

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Gene: RT1-Cl (RT1 class Ib, locus Cl) Rattus norvegicus
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Symbol: RT1-Cl
Name: RT1 class Ib, locus Cl
RGD ID: 3472
Description: PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; ammonium chloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MHC class I antigen; RT1 class Ib gene RT1-C-region (CI); RT1 class Ib gene, RT1-C-region (CI); RT1.A
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
UTH_Rnor_WKY_Bbb_1.0203,346,267 - 3,349,378 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
RGSC_v3.4202,116,560 - 2,134,175 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1203,552,628 - 3,578,046 (-)NCBI
Cytogenetic Map20 NCBI


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Sequence analysis of the promoter regions of the classical class I gene RT1.Al and two other class I genes of the rat MHC. Lambracht D and Wonigeit K, Immunogenetics 1995;41(6):375-9.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:1300430  


Genomics

Markers in Region
H2-D1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2204,908,501 - 4,908,657 (+)MAPPERmRatBN7.2
Rnor_6.0205,417,603 - 5,417,758NCBIRnor6.0
Rnor_5.0207,477,747 - 7,477,902UniSTSRnor5.0
RGSC_v3.4205,059,871 - 5,060,026UniSTSRGSC3.4
Celera206,492,138 - 6,492,293UniSTS
Celera20685,255 - 685,411UniSTS
Celera205,715,355 - 5,715,511UniSTS
Cytogenetic Map20p12UniSTS


Expression


Sequence


RefSeq Acc Id: NM_206848
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
RGSC_v3.4202,116,560 - 2,134,175 (-)RGD
Protein Sequences
Protein RefSeqs NP_996730 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB82285 (Get FASTA)   NCBI Sequence Viewer  
  ABS84943 (Get FASTA)   NCBI Sequence Viewer  
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.30.500.10 UniProtKB/TrEMBL
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC_I-like_Ag-recog UniProtKB/TrEMBL
  MHC_I-like_Ag-recog_sf UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  MHC_I_a_a1/a2 UniProtKB/TrEMBL
  MHC_I_a_C UniProtKB/TrEMBL
NCBI Gene 24977 ENTREZGENE
PANTHER CLASS IB MHC ANTIGEN QA-2-RELATED UniProtKB/TrEMBL
  MHC CLASS I-RELATED UniProtKB/TrEMBL
Pfam C1-set UniProtKB/TrEMBL
  MHC_I UniProtKB/TrEMBL
  MHC_I_C UniProtKB/TrEMBL
PharmGKB HLA-C RGD
PhenoGen RT1-Cl PhenoGen
PRINTS MHCCLASSI UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
SMART IGc1 UniProtKB/TrEMBL
Superfamily-SCOP MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt O19445 ENTREZGENE, UniProtKB/TrEMBL
  Q08680 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-11 RT1-2.5  RT1 class Ib, locus Cl  RT1-Cl  RT1 class Ib gene, RT1-C-region (CI)  Name updated 625702 APPROVED
2002-06-10 RT1-Cl  RT1 class Ib gene, RT1-C-region      Symbol and Name status set to approved 70586 APPROVED