IRF7 (interferon regulatory factor 7) - Rat Genome Database

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Gene: IRF7 (interferon regulatory factor 7) Pan paniscus
Analyze
Symbol: IRF7
Name: interferon regulatory factor 7
RGD ID: 329345260
Description: ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (inferred); DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN immunoglobulin mediated immune response (ortholog); positive regulation of type I interferon production (ortholog); positive regulation of type I interferon-mediated signaling pathway (ortholog); ASSOCIATED WITH Chanarin-Dorfman syndrome (ortholog); COVID-19 (ortholog); delta beta-thalassemia (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v292,991,578 - 2,994,429 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1112,207,772 - 2,210,627 (-)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl11647,827 - 651,314 (-)Ensemblpanpan1.1panPan2


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA)
cytoplasm  (IEA)
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA,ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IRF7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v292,991,578 - 2,994,429 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1112,207,772 - 2,210,627 (-)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl11647,827 - 651,314 (-)Ensemblpanpan1.1panPan2
IRF7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811612,555 - 615,950 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11612,553 - 615,983 (-)EnsemblGRCh38hg38GRCh38
GRCh3711612,555 - 615,950 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611602,555 - 605,999 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411602,590 - 605,650NCBI
Celera11677,701 - 681,146 (-)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11427,860 - 431,281 (-)NCBIHuRef
CHM1_111611,595 - 615,009 (-)NCBICHM1_1
T2T-CHM13v2.011661,201 - 664,566 (-)NCBIT2T-CHM13v2.0
Irf7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,843,096 - 140,846,412 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7140,842,619 - 140,846,394 (-)EnsemblGRCm39 Ensembl
GRCm387141,263,183 - 141,266,499 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,262,706 - 141,266,481 (-)EnsemblGRCm38mm10GRCm38
MGSCv377148,449,088 - 148,452,300 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367141,114,509 - 141,117,721 (-)NCBIMGSCv36mm8
Celera7141,056,921 - 141,060,133 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.57NCBI
Irf7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81205,796,956 - 205,800,543 (-)NCBIGRCr8
mRatBN7.21196,367,380 - 196,370,943 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,367,361 - 196,370,832 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1204,712,872 - 204,715,929 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01211,839,500 - 211,842,700 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01204,513,638 - 204,516,838 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01214,249,388 - 214,252,909 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,248,837 - 214,252,456 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,166,926 - 221,170,447 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,456,689 - 201,459,756 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11201,607,693 - 201,611,125 (-)NCBI
Celera1194,001,244 - 194,004,312 (-)NCBICelera
Cytogenetic Map1q41NCBI
Irf7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,443,272 - 11,445,657 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,442,781 - 11,445,706 (+)NCBIChiLan1.0ChiLan1.0
IRF7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha1825,356,590 - 25,359,121 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01826,292,147 - 26,294,695 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11825,801,663 - 25,804,207 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01825,446,631 - 25,449,156 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01826,058,831 - 26,061,390 (-)NCBIUU_Cfam_GSD_1.0
Irf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947445,336 - 448,848 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936888445,549 - 448,392 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936888445,340 - 448,801 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IRF7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2372,238 - 375,378 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12372,235 - 375,572 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22299,457 - 302,151 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IRF7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11430,412 - 433,959 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1429,310 - 432,925 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,490,795 - 97,493,977 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Irf7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476621,850,211 - 21,853,189 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000036776   ⟹   ENSPPAP00000014100
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11647,827 - 651,314 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000036784   ⟹   ENSPPAP00000014108
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11647,827 - 651,314 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000036790   ⟹   ENSPPAP00000014114
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11647,827 - 651,314 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000036804   ⟹   ENSPPAP00000014127
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11647,919 - 650,518 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000036812   ⟹   ENSPPAP00000014133
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11648,515 - 649,463 (-)Ensembl
RefSeq Acc Id: XM_055093923   ⟹   XP_054949898
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v292,991,578 - 2,994,279 (-)NCBI
NHGRI_mPanPan1112,207,772 - 2,210,477 (-)NCBI
RefSeq Acc Id: XM_055093924   ⟹   XP_054949899
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v292,991,578 - 2,994,429 (-)NCBI
NHGRI_mPanPan1112,207,772 - 2,210,627 (-)NCBI
RefSeq Acc Id: XM_055093925   ⟹   XP_054949900
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v292,991,578 - 2,994,429 (-)NCBI
NHGRI_mPanPan1112,207,772 - 2,210,627 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000014133   ⟸   ENSPPAT00000036812
RefSeq Acc Id: ENSPPAP00000014100   ⟸   ENSPPAT00000036776
RefSeq Acc Id: ENSPPAP00000014127   ⟸   ENSPPAT00000036804
RefSeq Acc Id: ENSPPAP00000014114   ⟸   ENSPPAT00000036790
RefSeq Acc Id: ENSPPAP00000014108   ⟸   ENSPPAT00000036784
RefSeq Acc Id: XP_054949900   ⟸   XM_055093925
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054949899   ⟸   XM_055093924
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054949898   ⟸   XM_055093923
- Peptide Label: isoform X1
Protein Domains
Interferon regulatory factor-3   IRF tryptophan pentad repeat


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030184 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036776.1 UniProtKB/TrEMBL
  ENSPPAT00000036784.1 UniProtKB/TrEMBL
  ENSPPAT00000036790.1 UniProtKB/TrEMBL
  ENSPPAT00000036804.1 UniProtKB/TrEMBL
  ENSPPAT00000036812.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.200.10 UniProtKB/TrEMBL
  Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain UniProtKB/TrEMBL
InterPro Interferon_reg_fac_CS UniProtKB/TrEMBL
  Interferon_reg_fact_DNA-bd_dom UniProtKB/TrEMBL
  Interferon_reg_factor-3 UniProtKB/TrEMBL
  SMAD-like_dom_sf UniProtKB/TrEMBL
  SMAD_FHA_dom_sf UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene IRF7 ENTREZGENE
PANTHER INTERFERON REGULATORY FACTOR UniProtKB/TrEMBL
  INTERFERON REGULATORY FACTOR 7 UniProtKB/TrEMBL
Pfam IRF UniProtKB/TrEMBL
  IRF-3 UniProtKB/TrEMBL
PRINTS INTFRNREGFCT UniProtKB/TrEMBL
PROSITE IRF_1 UniProtKB/TrEMBL
  IRF_2 UniProtKB/TrEMBL
SMART IRF UniProtKB/TrEMBL
  IRF-3 UniProtKB/TrEMBL
Superfamily-SCOP SMAD/FHA domain UniProtKB/TrEMBL
  Winged helix' DNA-binding domain UniProtKB/TrEMBL
UniProt A0A2R9AA14_PANPA UniProtKB/TrEMBL
  A0A2R9AA16_PANPA UniProtKB/TrEMBL
  A0A2R9AEZ7_PANPA UniProtKB/TrEMBL
  A0A2R9AF21_PANPA UniProtKB/TrEMBL
  A0A2R9AFI5_PANPA UniProtKB/TrEMBL
  A1YGK2_PANPA UniProtKB/TrEMBL
  A1YGK3_PANPA UniProtKB/TrEMBL