LOC129392969 (DDIT3 upstream open reading frame protein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: LOC129392969 (DDIT3 upstream open reading frame protein) Pan paniscus
Analyze
Symbol: LOC129392969 (Ensembl: DDIT3)
Name: DDIT3 upstream open reading frame protein (Ensembl:DNA damage inducible transcript 3)
RGD ID: 329331850
Description: ENCODES a protein that exhibits cAMP response element binding protein binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN anterior/posterior axis specification (inferred); apoptotic process (inferred); artery development (inferred); FOUND IN CHOP-ATF3 complex (inferred); CHOP-ATF4 complex (inferred); CHOP-C/EBP complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: uncharacterized LOC128125814 homolog
RGD Orthologs
Human
Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,820,405 - 36,824,073 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,817,419 - 36,820,844 (+)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl1231,664,743 - 31,668,701 (+)Ensemblpanpan1.1panPan2


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anterior/posterior axis specification  (IEA)
apoptotic process  (IEA)
artery development  (IEA)
blood vessel maturation  (IEA)
cell redox homeostasis  (IEA)
endoplasmic reticulum unfolded protein response  (IEA)
ER overload response  (IEA)
establishment of protein localization to mitochondrion  (IEA)
gene expression  (IEA)
HRI-mediated signaling  (IEA)
integrated stress response signaling  (IEA)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  (IEA)
intrinsic apoptotic signaling pathway in response to nitrosative stress  (IEA)
negative regulation of canonical Wnt signaling pathway  (IEA)
negative regulation of cold-induced thermogenesis  (IEA)
negative regulation of determination of dorsal identity  (IEA)
negative regulation of DNA-templated transcription  (IEA)
negative regulation of fat cell differentiation  (IEA)
negative regulation of interleukin-17 production  (IEA)
negative regulation of interleukin-4 production  (IEA)
negative regulation of myoblast differentiation  (IEA)
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA)
negative regulation of transcription by RNA polymerase II  (IEA)
negative regulation of type II interferon production  (IEA)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of interleukin-8 production  (IEA)
positive regulation of intrinsic apoptotic signaling pathway  (IEA)
positive regulation of neuron apoptotic process  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA)
proteasome-mediated ubiquitin-dependent protein catabolic process  (IEA)
regulation of cell cycle  (IEA)
regulation of DNA-templated transcription  (IEA)
regulation of transcription by RNA polymerase II  (IEA)
release of sequestered calcium ion into cytosol  (IEA)
response to endoplasmic reticulum stress  (IEA)
response to platelet-derived growth factor  (IEA)
response to starvation  (IEA)
response to unfolded protein  (IEA)
response to wounding  (IEA)
sensory perception of sound  (IEA)
vascular associated smooth muscle cell migration  (IEA)
vascular associated smooth muscle cell proliferation  (IEA)
Wnt signaling pathway  (IEA)

Cellular Component

References

Genomics

Comparative Map Data
LOC129392969
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,820,405 - 36,824,073 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,817,419 - 36,820,844 (+)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl1231,664,743 - 31,668,701 (+)Ensemblpanpan1.1panPan2
LOC128125814
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,517,712 - 57,520,480 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371257,911,495 - 57,914,263 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map12q13.3NCBI
T2T-CHM13v2.01257,485,940 - 57,488,708 (-)NCBIT2T-CHM13v2.0
LOC134479709
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8765,001,730 - 65,005,659 (+)NCBIGRCr8


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_003824863   ⟹   XP_003824911
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,820,437 - 36,823,850 (+)NCBI
NHGRI_mPanPan11236,817,419 - 36,820,621 (+)NCBI
RefSeq Acc Id: XM_008978497   ⟹   XP_008976745
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,820,499 - 36,823,850 (+)NCBI
NHGRI_mPanPan11236,817,419 - 36,820,621 (+)NCBI
RefSeq Acc Id: XM_008978498   ⟹   XP_008976746
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,820,447 - 36,823,850 (+)NCBI
NHGRI_mPanPan11236,817,419 - 36,820,621 (+)NCBI
RefSeq Acc Id: XM_055095487   ⟹   XP_054951462
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21036,820,405 - 36,824,073 (+)NCBI
NHGRI_mPanPan11236,817,419 - 36,820,844 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003824911 (Get FASTA)   NCBI Sequence Viewer  
  XP_008976745 (Get FASTA)   NCBI Sequence Viewer  
  XP_008976746 (Get FASTA)   NCBI Sequence Viewer  
  XP_054951462 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000022208.1
RefSeq Acc Id: XP_054951462   ⟸   XM_055095487
RefSeq Acc Id: XP_003824911   ⟸   XM_003824863
- Sequence:
RefSeq Acc Id: XP_008976745   ⟸   XM_008978497
- Sequence:
RefSeq Acc Id: XP_008976746   ⟸   XM_008978498
- Sequence:
Protein Domains
bZIP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034304 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045015.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
InterPro bZIP UniProtKB/TrEMBL
  DNA_damage_induc_transcript_3 UniProtKB/TrEMBL
NCBI Gene LOC129392969 ENTREZGENE
PANTHER DNA DAMAGE-INDUCIBLE TRANSCRIPT 3 DDIT3 UniProtKB/TrEMBL
  DNA DAMAGE-INDUCIBLE TRANSCRIPT 3 PROTEIN UniProtKB/TrEMBL
PIRSF C/EBPzeta_CHOP_DDIT3 UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/TrEMBL
SMART BRLZ UniProtKB/TrEMBL
UniProt A0A2R9AYQ3_PANPA UniProtKB/TrEMBL