PMS2P6 (PMS1 homolog 2, mismatch repair system component pseudogene 6) - Rat Genome Database

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Gene: PMS2P6 (PMS1 homolog 2, mismatch repair system component pseudogene 6) Homo sapiens
Analyze
No known orthologs.
Symbol: PMS2P6
Name: PMS1 homolog 2, mismatch repair system component pseudogene 6
RGD ID: 3277649
HGNC Page HGNC:33514
Description: Predicted to enable ATP hydrolysis activity and ATP-dependent DNA damage sensor activity. Predicted to be involved in mismatch repair and somatic hypermutation of immunoglobulin genes. Predicted to be part of MutLalpha complex.
Type: pseudo (Ensembl: unprocessed_pseudogene)
RefSeq Status: INFERRED
Previously known as: PMS2L14; PMS2L2; PMS2P2; PMS4
RGD Orthologs
Alliance Genes
More Info homologs ...
Related Functional Gene: PMS2  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38773,093,644 - 73,096,950 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl773,093,657 - 73,105,389 (+)EnsemblGRCh38hg38GRCh38
GRCh37774,953,657 - 74,956,959 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36774,790,975 - 74,794,884 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map7q11.23NCBI
CHM1_1774,883,284 - 74,887,181 (-)NCBICHM1_1
T2T-CHM13v2.0774,293,698 - 74,297,074 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2774,286,103 - 74,290,012 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:9847074   PMID:10101297   PMID:21873635  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:97
Count of miRNA genes:96
Interacting mature miRNAs:97
Transcripts:ENST00000333674
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium
Low 680 503 523 106 419 60 1520 299 739 58 665 684 56 343 869 2
Below cutoff 1221 1609 661 239 699 157 1799 1123 2007 84 397 524 84 617 1175 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000333674
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl773,093,657 - 73,105,389 (+)Ensembl
Protein Sequences
GenBank Protein BAA74754 (Get FASTA)   NCBI Sequence Viewer  
  O95744 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O95744-F1-model_v2 AlphaFold O95744 1-297 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:33514 AgrOrtholog
COSMIC PMS2P6 COSMIC
Ensembl Genes ENSG00000174384 Ensembl
GTEx ENSG00000174384 GTEx
HGNC ID HGNC:33514 ENTREZGENE
Human Proteome Map PMS2P6 Human Proteome Map
NCBI Gene 729453 ENTREZGENE
UniProt O95744 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-14 PMS2P6  PMS1 homolog 2, mismatch repair system component pseudogene 6    postmeiotic segregation increased 2 pseudogene 6  Symbol and/or name change 5135510 APPROVED
2011-07-27 PMS2P6  postmeiotic segregation increased 2 pseudogene 6  PMS2L14  postmeiotic segregation increased 2-like 14  Symbol and/or name change 5135510 APPROVED