ABCC6 (ATP binding cassette subfamily C member 6)

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Gene: ABCC6 (ATP binding cassette subfamily C member 6) Pan paniscus

Analyze

Symbol:

ABCC6

Name:

ATP binding cassette subfamily C member 6

RGD ID:

32733494

Description:

ENCODES a protein that exhibits ABC-type glutathione S-conjugate transporter activity (ortholog); ABC-type xenobiotic transporter activity (ortholog); ATP binding (ortholog); INVOLVED IN ATP transport (ortholog); cellular phosphate ion homeostasis (ortholog); drug transmembrane transport (ortholog); PARTICIPATES IN multidrug resistance-associated protein mediated transport pathway; ASSOCIATED WITH Animal Disease Models (ortholog); arterial calcification of infancy (ortholog); autistic disorder (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); lateral plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

multidrug resistance-associated protein 6

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Mhudiblu_PPA_v0	16	21,443,980 - 21,477,163 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Animal Disease Models (ISO)

arterial calcification of infancy (ISO)

autistic disorder (ISO)

beta thalassemia (ISO)

Colorectal Neoplasms (ISO)

coronary artery disease (ISO)

cutis laxa (ISO)

Disease Progression (ISO)

Experimental Arthritis (ISO)

eye disease (ISO)

Familial Thoracic Aortic Aneurysm 4 (ISO)

Generalized Arterial Calcification of Infancy, 2 (ISO)

intestinal volvulus (ISO)

nephrotic syndrome type 1 (ISO)

pseudoxanthoma elasticum (ISO)

schizophrenia (ISO)

Volvulus Of Midgut (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ATP transport (ISO)

cellular phosphate ion homeostasis (ISO)

drug transmembrane transport (ISO)

inorganic diphosphate transport (ISO)

leukotriene transport (ISO)

Cellular Component

apical plasma membrane (ISO)

basolateral plasma membrane (ISO)

lateral plasma membrane (ISO)

membrane (ISO)

nucleoplasm (ISO)

plasma membrane (ISO)

Molecular Function

ABC-type glutathione S-conjugate transporter activity (ISO)

ABC-type xenobiotic transporter activity (ISO)

ATP binding (ISO)

ATPase (ISO)

ATPase-coupled transmembrane transporter activity (ISO)

inorganic diphosphate transmembrane transporter activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

multidrug resistance-associated protein mediated transport pathway (ISO)

References

Genomics

Comparative Map Data

ABCC6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Mhudiblu_PPA_v0	16	21,443,980 - 21,477,163 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

ABCC6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	16	16,148,928 - 16,223,522 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p13 Ensembl	16	16,149,565 - 16,223,522 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	16	16,149,565 - 16,223,617 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	16	16,243,422 - 16,317,351 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	16,150,923 - 16,224,838 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	16	16,151,490 - 16,224,815	NCBI
Celera	16	15,923,582 - 15,972,084 (-)	NCBI
Cytogenetic Map	16	p13.11	NCBI
HuRef	16	15,637,406 - 15,701,476 (-)	NCBI		HuRef
HuRef	16	17,226,645 - 17,228,924 (+)	NCBI		HuRef
CHM1_1	16	18,669,848 - 18,691,347 (+)	NCBI		CHM1_1

Abcc6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	45,625,804 - 45,679,915 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	7	45,616,979 - 45,679,726 (-)	Ensembl
GRCm38	7	45,974,110 - 46,030,491 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	45,967,555 - 46,030,302 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	53,231,750 - 53,285,656 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	7	45,844,422 - 45,898,327 (-)	NCBI			mm8
MGSCv36	7	35,552,479 - 35,606,515 (-)	NCBI			mm8
Celera	7	41,445,055 - 41,502,729 (-)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	29.64	NCBI

Abcc6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	96,447,224 - 96,501,464 (-)	NCBI
Rnor_6.0 Ensembl	1	101,959,540 - 102,013,243 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	1	101,954,786 - 102,013,252 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	103,042,723 - 103,096,453 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	96,448,588 - 96,524,655 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	96,526,698 - 96,602,766 (-)	NCBI
Celera	1	90,699,816 - 90,752,348 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Abcc6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	865,238 - 922,221 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	865,292 - 921,739 (-)	NCBI	ChiLan1.0	ChiLan1.0

ABCC6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	6	27,798,835 - 27,848,689 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	6	27,800,060 - 27,849,170 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Abcc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936501	3,469,928 - 3,508,577 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ABCC6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	3	28,260,935 - 28,356,706 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	28,960,801 - 29,063,405 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ABCC6
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	15,169,725 - 15,243,731 (-)	NCBI
ChlSab1.1 Ensembl	5	15,168,156 - 15,242,811 (-)	Ensembl

Abcc6
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624782	590,174 - 640,576 (-)	NCBI

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_034939998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	SSBP01001823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

XM_034939998 ⟹ XP_034795889

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
Mhudiblu_PPA_v0	16	21,443,980 - 21,477,163 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_034795889	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_034795889 ⟸ XM_034939998

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	ABCC6	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations