QPRT (quinolinate phosphoribosyltransferase) - Rat Genome Database

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Gene: QPRT (quinolinate phosphoribosyltransferase) Pan paniscus
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Symbol: QPRT
Name: quinolinate phosphoribosyltransferase
RGD ID: 32727947
Description: ENCODES a protein that exhibits nicotinate-nucleotide diphosphorylase (carboxylating) activity (ortholog); INVOLVED IN NAD biosynthetic process (ortholog); quinolinate metabolic process (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; niacin metabolic pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 16p11.2 deletion syndrome, 593-kb (ortholog); FOUND IN catalytic complex (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nicotinate-nucleotide pyrophosphorylase [carboxylating]
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21830,429,278 - 30,448,926 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11635,778,256 - 35,796,841 (-)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl1630,049,806 - 30,070,469 (+)Ensemblpanpan1.1panPan2


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
QPRT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21830,429,278 - 30,448,926 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11635,778,256 - 35,796,841 (-)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl1630,049,806 - 30,070,469 (+)Ensemblpanpan1.1panPan2
QPRT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381629,679,008 - 29,698,699 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1629,663,279 - 29,698,699 (+)EnsemblGRCh38hg38GRCh38
GRCh371629,690,329 - 29,710,020 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361629,597,942 - 29,616,816 (+)NCBINCBI36Build 36hg18NCBI36
Build 341629,597,941 - 29,616,813NCBI
Celera1673,086,675 - 73,105,568 (-)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1627,351,724 - 27,370,618 (+)NCBIHuRef
CHM1_11630,702,266 - 30,721,120 (+)NCBICHM1_1
T2T-CHM13v2.01629,947,774 - 29,980,720 (+)NCBIT2T-CHM13v2.0
Qprt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,706,942 - 126,721,201 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,706,286 - 126,721,398 (-)EnsemblGRCm39 Ensembl
GRCm387127,107,770 - 127,122,029 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7127,107,114 - 127,122,226 (-)EnsemblGRCm38mm10GRCm38
MGSCv377134,251,284 - 134,265,543 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367126,898,918 - 126,913,177 (-)NCBIMGSCv36mm8
Celera7126,956,210 - 126,970,579 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.33NCBI
Qprt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,148,715 - 191,164,006 (-)NCBIGRCr8
mRatBN7.21181,718,189 - 181,733,486 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,718,190 - 181,733,486 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,069,579 - 190,084,822 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01197,255,666 - 197,270,909 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,924,049 - 189,939,606 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,544,262 - 198,559,556 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,544,262 - 198,559,568 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,534,747 - 205,550,129 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,358,523 - 186,374,681 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,508,404 - 186,524,562 (-)NCBI
Celera1179,371,205 - 179,386,496 (-)NCBICelera
Cytogenetic Map1q37NCBI
Qprt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554937,224,983 - 7,242,852 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554937,225,472 - 7,243,078 (-)NCBIChiLan1.0ChiLan1.0
QPRT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,778,664 - 17,794,110 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,779,439 - 17,794,035 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,355,777 - 19,371,193 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,913,305 - 17,928,517 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,914,017 - 17,928,916 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,712,824 - 17,728,246 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,628,300 - 17,643,725 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,944,000 - 17,959,189 (+)NCBIUU_Cfam_GSD_1.0
Qprt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344124,647,145 - 124,665,262 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650112,742,157 - 12,763,187 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650112,743,634 - 12,763,068 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
QPRT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl317,987,242 - 18,001,711 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1317,987,223 - 18,001,712 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2318,588,984 - 18,603,469 (-)NCBISscrofa10.2Sscrofa10.2susScr3
QPRT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,953,980 - 26,970,120 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl526,950,391 - 26,970,079 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660682,548,157 - 2,573,292 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000054271   ⟹   ENSPPAP00000031407
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1630,049,806 - 30,070,469 (+)Ensembl
RefSeq Acc Id: XM_008961601   ⟹   XP_008959849
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21830,429,285 - 30,448,926 (+)NCBI
NHGRI_mPanPan11635,778,256 - 35,796,834 (-)NCBI
RefSeq Acc Id: XM_024925811   ⟹   XP_024781579
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21830,429,278 - 30,448,926 (+)NCBI
NHGRI_mPanPan11635,778,256 - 35,796,841 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008959849 (Get FASTA)   NCBI Sequence Viewer  
  XP_024781579 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000031407.1
RefSeq Acc Id: XP_024781579   ⟸   XM_024925811
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008959849   ⟸   XM_008961601
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BY11 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000031407   ⟸   ENSPPAT00000054271
Protein Domains
Quinolinate phosphoribosyl transferase C-terminal   Quinolinate phosphoribosyl transferase N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038641 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054271.1 UniProtKB/TrEMBL
Gene3D-CATH Aldolase class I UniProtKB/TrEMBL
  Quinolinate phosphoribosyl transferase, N-terminal domain UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/TrEMBL
  NadC UniProtKB/TrEMBL
  NadC/ModD UniProtKB/TrEMBL
  Nicotinate_pribotase-like_C UniProtKB/TrEMBL
  Quinolinate_PRibosylTase_N_sf UniProtKB/TrEMBL
  Quinolinate_PRibosylTrfase_C UniProtKB/TrEMBL
  Quinolinate_PRibosylTrfase_N UniProtKB/TrEMBL
NCBI Gene QPRT ENTREZGENE
PANTHER NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] UniProtKB/TrEMBL
  NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] UniProtKB/TrEMBL
Pfam QRPTase_C UniProtKB/TrEMBL
  QRPTase_N UniProtKB/TrEMBL
PIRSF NadC_ModD UniProtKB/TrEMBL
Superfamily-SCOP Nicotinate/Quinolinate PRTase C-terminal domain-like UniProtKB/TrEMBL
  Nicotinate/Quinolinate PRTase N-terminal domain-like UniProtKB/TrEMBL
UniProt A0A2R9BY11 ENTREZGENE, UniProtKB/TrEMBL