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Gene: Npy5r (neuropeptide Y receptor Y5) Rattus norvegicus
Symbol: Npy5r
Name: neuropeptide Y receptor Y5
Description: Exhibits pancreatic polypeptide receptor activity and peptide YY receptor activity. Involved in several processes, including generation of ovulation cycle rhythm; negative regulation of GABAergic synaptic transmission; and regulation of acute inflammatory response. Localizes to cytoplasm. Used to study childhood absence epilepsy; hyperinsulinism; and visual epilepsy. Biomarker of coronary restenosis; obesity; and prolactinoma. Human ortholog(s) of this gene implicated in lipid metabolism disorder and obesity. Orthologous to human NPY5R (neuropeptide Y receptor Y5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitriptyline.
Type: protein-coding
Also known as: neuropeptide Y receptor type 5; neuropeptide Y5 receptor; NPY-Y5 receptor; NPY5-R; NPYR5; NPYY5-R; Y5 receptor
Homo sapiens (human) : NPY5R (neuropeptide Y receptor Y5)  HGNC  Alliance
Mus musculus (house mouse) : Npy5r (neuropeptide Y receptor Y5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npy5r (neuropeptide Y receptor Y5)
Pan paniscus (bonobo/pygmy chimpanzee) : NPY5R (neuropeptide Y receptor Y5)
Canis lupus familiaris (dog) : NPY5R (neuropeptide Y receptor Y5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npy5r (neuropeptide Y receptor Y5)
Sus scrofa (pig) : NPY5R (neuropeptide Y receptor Y5)
Chlorocebus sabaeus (African green monkey) : NPY5R (neuropeptide Y receptor Y5)
Heterocephalus glaber (naked mole-rat) : Npy5r (neuropeptide Y receptor Y5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01624,796,685 - 24,805,730 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1624,797,124 - 24,805,079 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01624,680,437 - 24,688,657 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41624,765,175 - 24,773,132 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11624,765,172 - 24,773,128 (+)NCBI
Celera1623,179,732 - 23,187,687 (+)NCBICelera
Cytogenetic Map16p14NCBI
RH 3.4 Map16280.0RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Npy5r
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3199
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.