Otulin (OTU deubiquitinase with linear linkage specificity) - Rat Genome Database

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Gene: Otulin (OTU deubiquitinase with linear linkage specificity) Rattus norvegicus
Analyze
Symbol: Otulin
Name: OTU deubiquitinase with linear linkage specificity
RGD ID: 2324500
Description: Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including protein linear deubiquitination; regulation of defense response; and regulation of signal transduction. Predicted to be part of LUBAC complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in otulipenia and primary immunodeficiency disease. Orthologous to human OTULIN (OTU deubiquitinase with linear linkage specificity); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fam105b; family with sequence similarity 105, member B; hypothetical protein LOC100362554; LOC100362554; ubiquitin thioesterase otulin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2278,290,437 - 78,316,633 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl278,290,959 - 78,316,422 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx285,378,457 - 85,403,803 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0283,500,189 - 83,525,533 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0278,532,540 - 78,557,960 (-)NCBIRnor_WKY
Rnor_6.0280,267,724 - 80,293,204 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl280,269,587 - 80,293,181 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0299,932,239 - 99,958,233 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4279,431,094 - 79,454,752 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera273,945,074 - 73,970,536 (-)NCBICelera
Cytogenetic Map2q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO)
LUBAC complex  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:23708998   PMID:23746843   PMID:23806334   PMID:23827681   PMID:24726323   PMID:24726327   PMID:26997266   PMID:27523608   PMID:27559085   PMID:29950720   PMID:33836646  


Genomics

Comparative Map Data
Otulin
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2278,290,437 - 78,316,633 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl278,290,959 - 78,316,422 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx285,378,457 - 85,403,803 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0283,500,189 - 83,525,533 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0278,532,540 - 78,557,960 (-)NCBIRnor_WKY
Rnor_6.0280,267,724 - 80,293,204 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl280,269,587 - 80,293,181 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0299,932,239 - 99,958,233 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4279,431,094 - 79,454,752 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera273,945,074 - 73,970,536 (-)NCBICelera
Cytogenetic Map2q22NCBI
OTULIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38514,664,718 - 14,716,525 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl514,664,664 - 14,699,850 (+)EnsemblGRCh38hg38GRCh38
GRCh37514,664,827 - 14,699,959 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36514,717,783 - 14,752,842 (+)NCBINCBI36Build 36hg18NCBI36
Celera514,688,765 - 14,723,825 (+)NCBICelera
Cytogenetic Map5p15.2NCBI
HuRef514,637,385 - 14,672,668 (+)NCBIHuRef
CHM1_1514,664,551 - 14,699,610 (+)NCBICHM1_1
T2T-CHM13v2.0514,604,209 - 14,639,341 (+)NCBIT2T-CHM13v2.0
Otulin
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391527,606,000 - 27,630,940 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1527,542,721 - 27,630,779 (-)EnsemblGRCm39 Ensembl
GRCm381527,597,055 - 27,630,977 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1527,542,635 - 27,630,693 (-)EnsemblGRCm38mm10GRCm38
MGSCv371527,535,674 - 27,560,448 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361527,550,644 - 27,564,262 (-)NCBIMGSCv36mm8
Celera1528,353,849 - 28,378,669 (-)NCBICelera
Cytogenetic Map15B1NCBI
Otulin
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554263,953,933 - 3,982,175 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554263,953,852 - 3,982,532 (+)NCBIChiLan1.0ChiLan1.0
OTULIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1514,810,187 - 14,857,597 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl514,809,539 - 14,837,750 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0514,969,432 - 15,017,666 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
OTULIN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.134119,307 - 159,419 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl34122,274 - 159,394 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha344,612,695 - 4,652,797 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03430,210 - 70,320 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3433,189 - 70,303 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13442,446 - 82,518 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03450,461 - 82,343 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.034284,839 - 324,953 (-)NCBIUU_Cfam_GSD_1.0
Otulin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213233,060,519 - 233,101,743 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366651,668,311 - 1,690,918 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049366651,654,045 - 1,690,955 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OTULIN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl164,063,071 - 4,093,198 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1164,063,037 - 4,097,112 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,402,784 - 4,436,591 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OTULIN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1414,358,556 - 14,395,539 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl414,358,538 - 14,389,987 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606414,137,064 - 14,174,630 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Otulin
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475111,676,850 - 11,702,061 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475111,676,932 - 11,703,143 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Otulin
122 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:168
Count of miRNA genes:128
Interacting mature miRNAs:137
Transcripts:ENSRNOT00000016111
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)243162366111362592Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24317101783575226Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)259134147127460910Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)259324377103795077Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)259324377103795077Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)259324377141596857Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)259324719102755241Rat
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)259846005104846005Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)264366971109366971Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
7411551Bw131Body weight QTL 13129.60.001body mass (VT:0001259)body weight gain (CMO:0000420)267942638112942638Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)27478666494359546Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)27478666494359546Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
61465Bp13Blood pressure QTL 133.3blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)276539322102785628Rat
61465Bp13Blood pressure QTL 133.3blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)276539322102785628Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)276539322150540526Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 32 50 41 19 41 66 27 35 11
Low 1 11 7 8 11 8 8 6 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000016111   ⟹   ENSRNOP00000016111
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl278,290,959 - 78,316,422 (-)Ensembl
Rnor_6.0 Ensembl280,269,587 - 80,293,181 (-)Ensembl
RefSeq Acc Id: NM_001302889   ⟹   NP_001289818
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2278,290,959 - 78,316,422 (-)NCBI
Rnor_6.0280,267,726 - 80,293,186 (-)NCBI
Celera273,945,074 - 73,970,536 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006232088   ⟹   XP_006232150
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2278,290,437 - 78,316,478 (-)NCBI
Rnor_6.0280,267,724 - 80,293,204 (-)NCBI
Rnor_5.0299,932,239 - 99,958,233 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039101540   ⟹   XP_038957468
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2278,293,378 - 78,316,633 (-)NCBI
RefSeq Acc Id: XM_039101541   ⟹   XP_038957469
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2278,290,437 - 78,316,337 (-)NCBI
RefSeq Acc Id: XM_039101542   ⟹   XP_038957470
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2278,290,437 - 78,316,322 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_006232150   ⟸   XM_006232088
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001289818   ⟸   NM_001302889
- UniProtKB: B0BMY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016111   ⟸   ENSRNOT00000016111
RefSeq Acc Id: XP_038957469   ⟸   XM_039101541
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038957470   ⟸   XM_039101542
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038957468   ⟸   XM_039101540
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BMY6-F1-model_v2 AlphaFold B0BMY6 1-353 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691209
Promoter ID:EPDNEW_R1730
Type:initiation region
Name:Otulin_1
Description:OTU deubiquitinase with linear linkage specificity
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0280,293,166 - 80,293,226EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2324500 AgrOrtholog
BioCyc Gene G2FUF-53913 BioCyc
Ensembl Genes ENSRNOG00000012017 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000016111 ENTREZGENE
  ENSRNOP00000016111.4 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016111 ENTREZGENE
  ENSRNOT00000016111.5 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1300.20 UniProtKB/TrEMBL
  3.30.200.60 UniProtKB/TrEMBL
InterPro FAM105 UniProtKB/TrEMBL
  FAM105B UniProtKB/TrEMBL
  Peptidase_C65_otubain_sub1 UniProtKB/TrEMBL
  Peptidase_C65_otubain_sub2 UniProtKB/TrEMBL
KEGG Report rno:100362554 UniProtKB/TrEMBL
NCBI Gene 100362554 ENTREZGENE
PANTHER PTHR33662 UniProtKB/TrEMBL
Pfam Peptidase_C101 UniProtKB/TrEMBL
PhenoGen Otulin PhenoGen
PRINTS PROTEINF105 UniProtKB/TrEMBL
  PROTEINF105B UniProtKB/TrEMBL
UniProt B0BMY6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-21 Otulin  OTU deubiquitinase with linear linkage specificity  Fam105b  family with sequence similarity 105, member B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-08-29 Fam105b  family with sequence similarity 105, member B  LOC100362554  hypothetical protein LOC100362554  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100362554  hypothetical protein LOC100362554      Symbol and Name status set to provisional 70820 PROVISIONAL