Ankrd31 (ankyrin repeat domain 31) - Rat Genome Database

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Gene: Ankrd31 (ankyrin repeat domain 31) Rattus norvegicus
Analyze
Symbol: Ankrd31
Name: ankyrin repeat domain 31
RGD ID: 2323520
Description: Predicted to be involved in homologous chromosome pairing at meiosis; meiotic DNA double-strand break formation involved in reciprocal meiotic recombination; and positive regulation of meiotic DNA double-strand break formation. Predicted to be located in chromatin. Orthologous to human ANKRD31 (ankyrin repeat domain 31); INTERACTS WITH bisphenol A; 2,3',4,4',5-Pentachlorobiphenyl (ortholog); 2-hydroxypropanoic acid (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AABR07007769.1; ankyrin repeat domain-containing protein 31; LOC100359720; putative ankyrin repeat domain-containing protein 31; rCG64386-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8229,793,882 - 29,987,621 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl229,813,940 - 29,977,149 (+)EnsemblGRCr8
mRatBN7.2228,079,187 - 28,241,722 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl228,092,882 - 28,241,719 (+)EnsemblmRatBN7.2
Rnor_6.0227,571,129 - 27,743,668 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,630,285 - 27,742,903 (+)NCBIrn6Rnor6.0
Rnor_5.0246,685,460 - 46,808,211 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4227,305,641 - 27,357,967 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera224,137,300 - 24,286,039 (+)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:31000436   PMID:31003867  


Genomics

Comparative Map Data
Ankrd31
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8229,793,882 - 29,987,621 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl229,813,940 - 29,977,149 (+)EnsemblGRCr8
mRatBN7.2228,079,187 - 28,241,722 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl228,092,882 - 28,241,719 (+)EnsemblmRatBN7.2
Rnor_6.0227,571,129 - 27,743,668 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,630,285 - 27,742,903 (+)NCBIrn6Rnor6.0
Rnor_5.0246,685,460 - 46,808,211 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4227,305,641 - 27,357,967 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera224,137,300 - 24,286,039 (+)NCBICelera
Cytogenetic Map2q12NCBI
ANKRD31
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38575,068,297 - 75,236,878 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl575,068,275 - 75,236,911 (-)Ensemblhg38GRCh38
GRCh37574,364,122 - 74,532,703 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36574,477,548 - 74,568,459 (-)NCBIBuild 36Build 36hg18NCBI36
Celera570,258,290 - 70,426,854 (-)NCBICelera
Cytogenetic Map5q13.3NCBI
HuRef569,568,973 - 69,737,859 (-)NCBIHuRef
CHM1_1573,796,900 - 73,965,446 (-)NCBICHM1_1
T2T-CHM13v2.0575,549,155 - 75,717,764 (-)NCBIT2T-CHM13v2.0
Ankrd31
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391396,884,797 - 97,046,302 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1396,884,780 - 97,046,547 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381396,748,289 - 96,909,794 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1396,748,272 - 96,910,039 (+)Ensemblmm10GRCm38
MGSCv371397,556,557 - 97,716,432 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361397,887,301 - 98,047,176 (+)NCBIMGSCv36mm8
Celera13100,385,066 - 100,546,267 (+)NCBICelera
Cytogenetic Map13D1NCBI
Ankrd31
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,483,715 - 25,626,546 (+)Ensembl
ChiLan1.0NW_00495542525,483,400 - 25,647,904 (+)NCBIChiLan1.0ChiLan1.0
ANKRD31
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2440,061,708 - 40,240,930 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1538,215,340 - 38,394,562 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0540,060,599 - 40,236,468 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1540,673,567 - 40,849,519 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl540,673,567 - 40,849,519 (+)EnsemblpanPan2panpan1.1
ANKRD31
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1331,067,936 - 31,188,066 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl331,028,026 - 31,186,827 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha332,311,195 - 32,397,596 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0330,998,148 - 31,117,402 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl330,997,894 - 31,117,415 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1330,928,185 - 31,047,350 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0330,899,798 - 31,018,980 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0331,276,930 - 31,396,110 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ankrd31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213189,245,655 - 189,408,577 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365491,450,561 - 1,612,167 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365491,450,490 - 1,612,151 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKRD31
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl284,149,358 - 84,366,190 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1284,148,363 - 84,320,823 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,773,614 - 85,907,800 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANKRD31
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1469,433,974 - 69,597,267 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604918,212,169 - 18,381,066 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ankrd31
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624951331,389 - 556,856 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624951290,203 - 557,210 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ankrd31
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13222,791,559 - 222,931,052 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ankrd31
1502 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21332504158325041Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22411781369117813Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2142977529Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
9590080Insglur4Insulin/glucose ratio QTL 428.70.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)2615276751152767Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21605188361051883Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22203804467038044Rat
731166Mamtr2Mammary tumor resistance QTL 20.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358154623581Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22888999173889991Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21436870759368707Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358144538110Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)2573632550736325Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21822713763227137Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266673652666Rat

Markers in Region
D2Ulb23  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2228,172,121 - 28,172,253 (+)MAPPERmRatBN7.2
Rnor_6.0227,660,824 - 27,660,953NCBIRnor6.0
Rnor_5.0246,774,674 - 46,774,803UniSTSRnor5.0
RGSC_v3.4227,331,893 - 27,332,022UniSTSRGSC3.4
Celera224,215,824 - 24,215,957UniSTS
Cytogenetic Map2 RGD


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
sensory system
visual system
2 1 3 2 10 3 5 5 1 3 3

Sequence


Ensembl Acc Id: ENSRNOT00000032960   ⟹   ENSRNOP00000034334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl229,813,940 - 29,977,149 (+)Ensembl
mRatBN7.2 Ensembl228,092,882 - 28,241,719 (+)Ensembl
RefSeq Acc Id: XM_039103463   ⟹   XP_038959391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,793,882 - 29,987,621 (+)NCBI
mRatBN7.2228,079,188 - 28,241,722 (+)NCBI
RefSeq Acc Id: XM_039103464   ⟹   XP_038959392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,797,807 - 29,987,621 (+)NCBI
mRatBN7.2228,079,187 - 28,241,722 (+)NCBI
RefSeq Acc Id: XM_039103465   ⟹   XP_038959393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,868,043 - 29,987,621 (+)NCBI
mRatBN7.2228,133,408 - 28,241,722 (+)NCBI
RefSeq Acc Id: XM_063282675   ⟹   XP_063138745
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,797,807 - 29,987,621 (+)NCBI
RefSeq Acc Id: XM_063282676   ⟹   XP_063138746
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,793,882 - 29,987,621 (+)NCBI
RefSeq Acc Id: XM_063282677   ⟹   XP_063138747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,806,671 - 29,987,621 (+)NCBI
RefSeq Acc Id: XM_063282678   ⟹   XP_063138748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,797,807 - 29,987,621 (+)NCBI
RefSeq Acc Id: XM_063282679   ⟹   XP_063138749
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,797,807 - 29,987,621 (+)NCBI
RefSeq Acc Id: XP_038959392   ⟸   XM_039103464
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959391   ⟸   XM_039103463
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038959393   ⟸   XM_039103465
- Peptide Label: isoform X5
- UniProtKB: F1LX87 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000034334   ⟸   ENSRNOT00000032960
RefSeq Acc Id: XP_063138746   ⟸   XM_063282676
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063138745   ⟸   XM_063282675
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063138748   ⟸   XM_063282678
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063138749   ⟸   XM_063282679
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063138747   ⟸   XM_063282677
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LX87-F1-model_v2 AlphaFold F1LX87 1-729 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2323520 AgrOrtholog
BioCyc Gene G2FUF-54776 BioCyc
Ensembl Genes ENSRNOG00000025321 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032960 ENTREZGENE
  ENSRNOT00000032960.7 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro ANKRD31 UniProtKB/TrEMBL
  Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  RAMA UniProtKB/TrEMBL
NCBI Gene 100359720 ENTREZGENE
PANTHER ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 31 UniProtKB/TrEMBL
  PTHR24176 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  RAMA UniProtKB/TrEMBL
PhenoGen Ankrd31 PhenoGen
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025321 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt F1LX87 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Ankrd31  ankyrin repeat domain 31  AABR07007769.1    Data merged from RGD:15003611 737654 PROVISIONAL
2019-11-08 AABR07007769.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2014-07-23 Ankrd31  ankyrin repeat domain 31  LOC100359720  rCG64386-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100359720  rCG64386-like      Symbol and Name status set to provisional 70820 PROVISIONAL