Ankrd31 (ankyrin repeat domain 31) - Rat Genome Database

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Gene: Ankrd31 (ankyrin repeat domain 31) Rattus norvegicus
Analyze
Symbol: Ankrd31
Name: ankyrin repeat domain 31
RGD ID: 2323520
Description: Predicted to be involved in homologous chromosome pairing at meiosis; meiotic DNA double-strand break formation involved in reciprocal meiotic recombination; and positive regulation of meiotic DNA double-strand break formation. Predicted to be part of chromatin. Orthologous to human ANKRD31 (ankyrin repeat domain 31); INTERACTS WITH bisphenol A; 2,3',4,4',5-Pentachlorobiphenyl (ortholog); 2-hydroxypropanoic acid (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AABR07007769.1; ankyrin repeat domain-containing protein 31; LOC100359720; putative ankyrin repeat domain-containing protein 31; rCG64386-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8229,793,882 - 29,987,621 (+)NCBIGRCr8
mRatBN7.2228,079,187 - 28,241,722 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl228,092,882 - 28,241,719 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0227,571,129 - 27,743,668 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,630,285 - 27,742,903 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0246,685,460 - 46,808,211 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4227,305,641 - 27,357,967 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera224,137,300 - 24,286,039 (+)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:31000436   PMID:31003867  


Genomics

Comparative Map Data
Ankrd31
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8229,793,882 - 29,987,621 (+)NCBIGRCr8
mRatBN7.2228,079,187 - 28,241,722 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl228,092,882 - 28,241,719 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0227,571,129 - 27,743,668 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,630,285 - 27,742,903 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0246,685,460 - 46,808,211 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4227,305,641 - 27,357,967 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera224,137,300 - 24,286,039 (+)NCBICelera
Cytogenetic Map2q12NCBI
ANKRD31
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38575,068,297 - 75,236,878 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl575,068,275 - 75,236,911 (-)EnsemblGRCh38hg38GRCh38
GRCh37574,364,122 - 74,532,703 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36574,477,548 - 74,568,459 (-)NCBINCBI36Build 36hg18NCBI36
Celera570,258,290 - 70,426,854 (-)NCBICelera
Cytogenetic Map5q13.3NCBI
HuRef569,568,973 - 69,737,859 (-)NCBIHuRef
CHM1_1573,796,900 - 73,965,446 (-)NCBICHM1_1
T2T-CHM13v2.0575,549,155 - 75,717,764 (-)NCBIT2T-CHM13v2.0
Ankrd31
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391396,884,797 - 97,046,302 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1396,884,780 - 97,046,547 (+)EnsemblGRCm39 Ensembl
GRCm381396,748,289 - 96,909,794 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1396,748,272 - 96,910,039 (+)EnsemblGRCm38mm10GRCm38
MGSCv371397,556,557 - 97,716,432 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361397,887,301 - 98,047,176 (+)NCBIMGSCv36mm8
Celera13100,385,066 - 100,546,267 (+)NCBICelera
Cytogenetic Map13D1NCBI
Ankrd31
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,483,715 - 25,626,546 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542525,483,400 - 25,647,904 (+)NCBIChiLan1.0ChiLan1.0
ANKRD31
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2440,061,708 - 40,240,930 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1538,215,340 - 38,394,562 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0540,060,599 - 40,236,468 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1540,673,567 - 40,849,519 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl540,673,567 - 40,849,519 (+)Ensemblpanpan1.1panPan2
ANKRD31
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1331,067,936 - 31,188,066 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl331,028,026 - 31,186,827 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha332,311,195 - 32,397,596 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0330,998,148 - 31,117,402 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl330,997,894 - 31,117,415 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1330,928,185 - 31,047,350 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0330,899,798 - 31,018,980 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0331,276,930 - 31,396,110 (+)NCBIUU_Cfam_GSD_1.0
Ankrd31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213189,245,655 - 189,408,577 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365491,450,561 - 1,612,167 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365491,450,490 - 1,612,151 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKRD31
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl284,149,363 - 84,320,798 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1284,148,363 - 84,320,823 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,773,614 - 85,907,800 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANKRD31
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1469,433,974 - 69,597,267 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604918,212,169 - 18,381,066 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ankrd31
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624951331,389 - 556,856 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624951290,203 - 557,210 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ankrd31
471 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631682Bp115Blood pressure QTL 1154.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2137410502Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22699957143154682Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)21185206249003364Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2141244106Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2788777242804738Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1643006Pain1Pain QTL 13.630.005mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)22699957148268661Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat

Markers in Region
D2Ulb23  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2228,172,121 - 28,172,253 (+)MAPPERmRatBN7.2
Rnor_6.0227,660,824 - 27,660,953NCBIRnor6.0
Rnor_5.0246,774,674 - 46,774,803UniSTSRnor5.0
RGSC_v3.4227,331,893 - 27,332,022UniSTSRGSC3.4
Celera224,215,824 - 24,215,957UniSTS
Cytogenetic Map2 RGD


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000032960   ⟹   ENSRNOP00000034334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl228,092,882 - 28,241,719 (+)Ensembl
RefSeq Acc Id: XM_039103463   ⟹   XP_038959391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,793,882 - 29,987,621 (+)NCBI
mRatBN7.2228,079,188 - 28,241,722 (+)NCBI
RefSeq Acc Id: XM_039103464   ⟹   XP_038959392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,797,807 - 29,987,621 (+)NCBI
mRatBN7.2228,079,187 - 28,241,722 (+)NCBI
RefSeq Acc Id: XM_039103465   ⟹   XP_038959393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,868,043 - 29,987,621 (+)NCBI
mRatBN7.2228,133,408 - 28,241,722 (+)NCBI
RefSeq Acc Id: XM_063282675   ⟹   XP_063138745
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,797,807 - 29,987,621 (+)NCBI
RefSeq Acc Id: XM_063282676   ⟹   XP_063138746
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,793,882 - 29,987,621 (+)NCBI
RefSeq Acc Id: XM_063282677   ⟹   XP_063138747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,806,671 - 29,987,621 (+)NCBI
RefSeq Acc Id: XM_063282678   ⟹   XP_063138748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,797,807 - 29,987,621 (+)NCBI
RefSeq Acc Id: XM_063282679   ⟹   XP_063138749
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8229,797,807 - 29,987,621 (+)NCBI
RefSeq Acc Id: XP_038959392   ⟸   XM_039103464
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959391   ⟸   XM_039103463
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038959393   ⟸   XM_039103465
- Peptide Label: isoform X5
- UniProtKB: F1LX87 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000034334   ⟸   ENSRNOT00000032960
RefSeq Acc Id: XP_063138746   ⟸   XM_063282676
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063138745   ⟸   XM_063282675
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063138748   ⟸   XM_063282678
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063138749   ⟸   XM_063282679
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063138747   ⟸   XM_063282677
- Peptide Label: isoform X1
Protein Domains
RAMA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LX87-F1-model_v2 AlphaFold F1LX87 1-729 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2323520 AgrOrtholog
BioCyc Gene G2FUF-54776 BioCyc
Ensembl Genes ENSRNOG00000025321 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032960.6 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro ANKRD31 UniProtKB/TrEMBL
  Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  RAMA UniProtKB/TrEMBL
NCBI Gene 100359720 ENTREZGENE
PANTHER ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 31 UniProtKB/TrEMBL
  PTHR24176 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  RAMA UniProtKB/TrEMBL
PhenoGen Ankrd31 PhenoGen
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025321 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt F1LX87 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Ankrd31  ankyrin repeat domain 31  AABR07007769.1    Data merged from RGD:15003611 737654 PROVISIONAL
2019-11-08 AABR07007769.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2014-07-23 Ankrd31  ankyrin repeat domain 31  LOC100359720  rCG64386-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100359720  rCG64386-like      Symbol and Name status set to provisional 70820 PROVISIONAL