Adgra2 (adhesion G protein-coupled receptor A2) - Rat Genome Database

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Gene: Adgra2 (adhesion G protein-coupled receptor A2) Rattus norvegicus
Analyze
Symbol: Adgra2
Name: adhesion G protein-coupled receptor A2
RGD ID: 2323365
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including endothelial cell migration; positive regulation of canonical Wnt signaling pathway; and sprouting angiogenesis. Predicted to act upstream of or within several processes, including negative regulation of vascular endothelial growth factor signaling pathway; positive regulation of endothelial cell migration; and regulation of establishment of blood-brain barrier. Predicted to be located in cell surface. Predicted to be part of Wnt signalosome. Predicted to be active in plasma membrane. Orthologous to human ADGRA2 (adhesion G protein-coupled receptor A2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; lidocaine.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: G protein-coupled receptor 124; Gpr124; LOC100363275; LOC306543
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21664,932,964 - 64,971,433 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1664,933,315 - 64,971,483 (-)Ensembl
Rnor_6.01669,094,587 - 69,133,015 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1669,095,936 - 69,132,584 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01668,768,542 - 68,806,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41669,255,045 - 69,293,208 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1662,852,507 - 62,890,663 (-)NCBICelera
Cytogenetic Map16q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21071672   PMID:21421844   PMID:23918385   PMID:28288111   PMID:28678544   PMID:28803732   PMID:30026314  


Genomics

Comparative Map Data
Adgra2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21664,932,964 - 64,971,433 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1664,933,315 - 64,971,483 (-)Ensembl
Rnor_6.01669,094,587 - 69,133,015 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1669,095,936 - 69,132,584 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01668,768,542 - 68,806,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41669,255,045 - 69,293,208 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1662,852,507 - 62,890,663 (-)NCBICelera
Cytogenetic Map16q12.3NCBI
ADGRA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38837,796,883 - 37,844,896 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl837,784,191 - 37,844,896 (+)EnsemblGRCh38hg38GRCh38
GRCh37837,654,401 - 37,702,414 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36837,773,932 - 37,820,650 (+)NCBINCBI36hg18NCBI36
Build 34837,773,931 - 37,820,650NCBI
Celera836,605,963 - 36,653,084 (+)NCBI
Cytogenetic Map8p11.23NCBI
HuRef836,189,286 - 36,236,033 (+)NCBIHuRef
CHM1_1837,855,880 - 37,902,951 (+)NCBICHM1_1
T2T-CHM13v2.0838,073,278 - 38,121,297 (+)NCBI
Adgra2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39827,575,546 - 27,613,464 (+)NCBIGRCm39mm39
GRCm39 Ensembl827,575,611 - 27,613,464 (+)Ensembl
GRCm38827,085,520 - 27,123,436 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl827,085,583 - 27,123,436 (+)EnsemblGRCm38mm10GRCm38
MGSCv37828,196,313 - 28,233,894 (+)NCBIGRCm37mm9NCBIm37
MGSCv36828,551,777 - 28,589,358 (+)NCBImm8
Celera828,575,397 - 28,613,080 (+)NCBICelera
Cytogenetic Map8A2NCBI
Adgra2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546313,514,082 - 13,548,339 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546313,514,065 - 13,549,806 (+)NCBIChiLan1.0ChiLan1.0
ADGRA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1834,275,651 - 34,321,836 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl834,276,267 - 34,321,836 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0837,098,486 - 37,144,437 (+)NCBIMhudiblu_PPA_v0panPan3
ADGRA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11627,547,722 - 27,583,069 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1627,549,308 - 27,583,070 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1628,066,037 - 28,099,848 (-)NCBI
ROS_Cfam_1.01629,448,402 - 29,482,344 (-)NCBI
ROS_Cfam_1.0 Ensembl1629,446,278 - 29,483,197 (-)Ensembl
UMICH_Zoey_3.11627,668,324 - 27,703,792 (-)NCBI
UNSW_CanFamBas_1.01628,245,885 - 28,281,475 (-)NCBI
UU_Cfam_GSD_1.01628,285,068 - 28,320,567 (-)NCBI
Adgra2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494350,164,990 - 50,203,129 (-)NCBI
SpeTri2.0NW_0049367101,258,088 - 1,296,346 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1548,573,197 - 48,610,668 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11548,572,953 - 48,611,034 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21555,689,430 - 55,727,513 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1835,834,840 - 35,879,851 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl835,834,876 - 35,878,233 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660526,124,512 - 6,170,638 (-)NCBIVero_WHO_p1.0
Adgra2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247805,752,846 - 5,793,846 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247805,757,535 - 5,793,794 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
BF390610  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21664,932,830 - 64,932,986 (+)MAPPERmRatBN7.2
Rnor_6.01669,094,452 - 69,094,607NCBIRnor6.0
Rnor_5.01668,768,407 - 68,768,562UniSTSRnor5.0
RGSC_v3.41669,254,912 - 69,255,067UniSTSRGSC3.4
Celera1662,852,372 - 62,852,527UniSTS
RH 3.4 Map16593.7UniSTS
Cytogenetic Map16q12.4UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162173597566735975Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)162432551369325513Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)162515279370152793Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163528887080288870Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)163775215682752156Rat
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165272646484729064Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165272646484729064Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165272646484729064Rat
631525Pia14Pristane induced arthritis QTL 144.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)165571108783402471Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:56
Interacting mature miRNAs:60
Transcripts:ENSRNOT00000017776
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 30 13 12 4 12 1 1 62 22 33 11 1
Low 3 13 43 28 15 28 7 10 12 13 7 7
Below cutoff 1 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000017776   ⟹   ENSRNOP00000017776
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1664,933,315 - 64,971,483 (-)Ensembl
Rnor_6.0 Ensembl1669,095,936 - 69,132,584 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095677   ⟹   ENSRNOP00000082075
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1664,933,315 - 64,971,483 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096010   ⟹   ENSRNOP00000081432
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1664,933,315 - 64,971,483 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102332   ⟹   ENSRNOP00000079435
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1664,933,315 - 64,971,483 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109034   ⟹   ENSRNOP00000090414
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1664,933,315 - 64,971,483 (-)Ensembl
RefSeq Acc Id: XM_003751617   ⟹   XP_003751665
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21664,932,964 - 64,971,433 (-)NCBI
Rnor_6.01669,094,587 - 69,133,015 (-)NCBI
Rnor_5.01668,768,542 - 68,806,384 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006253295   ⟹   XP_006253357
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21664,932,964 - 64,971,433 (-)NCBI
Rnor_6.01669,094,587 - 69,133,015 (-)NCBI
Rnor_5.01668,768,542 - 68,806,384 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600376   ⟹   XP_017455865
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21664,932,964 - 64,971,433 (-)NCBI
Rnor_6.01669,094,587 - 69,133,015 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039095155   ⟹   XP_038951083
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21664,936,366 - 64,971,432 (-)NCBI
RefSeq Acc Id: XR_005494961
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21664,935,456 - 64,971,432 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003751665 (Get FASTA)   NCBI Sequence Viewer  
  XP_006253357 (Get FASTA)   NCBI Sequence Viewer  
  XP_017455865 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951083 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM09091 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003751665   ⟸   XM_003751617
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006253357   ⟸   XM_006253295
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017455865   ⟸   XM_017600376
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000017776   ⟸   ENSRNOT00000017776
RefSeq Acc Id: XP_038951083   ⟸   XM_039095155
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000082075   ⟸   ENSRNOT00000095677
RefSeq Acc Id: ENSRNOP00000081432   ⟸   ENSRNOT00000096010
RefSeq Acc Id: ENSRNOP00000090414   ⟸   ENSRNOT00000109034
RefSeq Acc Id: ENSRNOP00000079435   ⟸   ENSRNOT00000102332

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ADC7-F1-model_v2 AlphaFold D4ADC7 1-1336 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700159
Promoter ID:EPDNEW_R10678
Type:initiation region
Name:Adgra2_1
Description:adhesion G protein-coupled receptor A2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01669,132,665 - 69,132,725EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
16 69096714 69096715 C A snv MR/N (MCW)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
16 68770669 68770670 C A snv MR/N (KNAW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2323365 AgrOrtholog
BioCyc Gene G2FUF-11032 BioCyc
Ensembl Genes ENSRNOG00000012991 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000017776 ENTREZGENE
  ENSRNOP00000017776.5 UniProtKB/TrEMBL
  ENSRNOP00000079435.1 UniProtKB/TrEMBL
  ENSRNOP00000081432 ENTREZGENE
  ENSRNOP00000081432.1 UniProtKB/TrEMBL
  ENSRNOP00000082075.1 UniProtKB/TrEMBL
  ENSRNOP00000090414.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017776 ENTREZGENE
  ENSRNOT00000017776.6 UniProtKB/TrEMBL
  ENSRNOT00000095677.1 UniProtKB/TrEMBL
  ENSRNOT00000096010 ENTREZGENE
  ENSRNOT00000096010.1 UniProtKB/TrEMBL
  ENSRNOT00000102332.1 UniProtKB/TrEMBL
  ENSRNOT00000109034.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.220.50 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
  4.10.1240.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/TrEMBL
  GPS_dom UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
NCBI Gene 100363275 ENTREZGENE
Pfam 7tm_2 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PhenoGen Adgra2 PhenoGen
PROSITE G_PROTEIN_RECEP_F2_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART GPS UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF111418 UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0A8I5ZMQ6_RAT UniProtKB/TrEMBL
  A0A8I5ZUG3_RAT UniProtKB/TrEMBL
  A0A8I6G7Z0_RAT UniProtKB/TrEMBL
  A0A8I6GIV5_RAT UniProtKB/TrEMBL
  D4ADC7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-16 Adgra2  adhesion G protein-coupled receptor A2  Gpr124  G protein-coupled receptor 124  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-07 LOC100363275  G protein-coupled receptor 124  Gpr124  G protein-coupled receptor 124  Data Merged 737654 APPROVED
2013-08-07 Gpr124  G protein-coupled receptor 124  LOC100363275  G protein-coupled receptor 124  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100363275  G protein-coupled receptor 124      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Gpr124  G protein-coupled receptor 124   Gpr124_predicted  G protein-coupled receptor 124 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Gpr124_predicted  G protein-coupled receptor 124 (predicted)      Symbol and Name status set to approved 70820 APPROVED