Btbd8 (BTB domain containing 8) - Rat Genome Database

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Gene: Btbd8 (BTB domain containing 8) Rattus norvegicus
Analyze
Symbol: Btbd8
Name: BTB domain containing 8
RGD ID: 2321418
Description: Predicted to be involved in clathrin-dependent synaptic vesicle endocytosis; neuron projection development; and synaptic vesicle budding from endosome. Located in neuron projection terminus and synaptic vesicle. Orthologous to human BTBD8 (BTB domain containing 8); INTERACTS WITH Brodifacoum; glyphosate; (+)-catechin (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: BTB (POZ) domain containing 8; BTB (POZ) domain containing 8-like; BTB/POZ domain-containing protein 8; LOC100364240; LOC305122; LOC689994; LOC690003; similar to BTB (POZ) domain containing 8; similar to H43E16.1; uncharacterized protein KIAA1107
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2142,265,189 - 2,338,426 (-)NCBI
Rnor_6.0 Ensembl143,284,089 - 3,300,200 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0143,282,422 - 3,351,740 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0143,285,858 - 3,355,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,846,003 - 2,897,088 (-)NCBIRGSC3.4rn4RGSC3.4
Celera142,293,640 - 2,351,955 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
AP-2 adaptor complex  (IDA,ISO)
axon  (ISO,ISS)
cell body  (ISO,ISS)
neuron projection terminus  (IDA)
nucleoplasm  (ISO)
presynapse  (IEA,ISO)
synapse  (ISO)
synaptic vesicle  (IDA)

Molecular Function

References


Genomics

Comparative Map Data
Btbd8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2142,265,189 - 2,338,426 (-)NCBI
Rnor_6.0 Ensembl143,284,089 - 3,300,200 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0143,282,422 - 3,351,740 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0143,285,858 - 3,355,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,846,003 - 2,897,088 (-)NCBIRGSC3.4rn4RGSC3.4
Celera142,293,640 - 2,351,955 (-)NCBICelera
Cytogenetic Map14p22NCBI
BTBD8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl192,080,305 - 92,184,725 (+)EnsemblGRCh38hg38GRCh38
GRCh38192,080,345 - 92,188,509 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37192,545,902 - 92,650,280 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36192,318,481 - 92,385,985 (+)NCBINCBI36hg18NCBI36
Build 34192,257,913 - 92,325,414NCBI
Celera190,792,299 - 90,859,815 (+)NCBI
Cytogenetic Map1p22.1NCBI
HuRef190,666,116 - 90,733,635 (+)NCBIHuRef
CHM1_1192,660,686 - 92,728,226 (+)NCBICHM1_1
Btbd8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395107,585,796 - 107,660,426 (+)NCBIGRCm39mm39
GRCm39 Ensembl5107,585,863 - 107,659,073 (+)Ensembl
GRCm385107,437,930 - 107,512,560 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5107,437,997 - 107,511,207 (+)EnsemblGRCm38mm10GRCm38
MGSCv375107,867,016 - 107,920,615 (+)NCBIGRCm37mm9NCBIm37
MGSCv365107,678,299 - 107,731,898 (+)NCBImm8
Celera5104,551,274 - 104,604,857 (+)NCBICelera
Cytogenetic Map5FNCBI
BTBD8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1193,483,702 - 93,587,229 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,569,680 - 93,587,229 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0194,739,780 - 94,843,172 (+)NCBIMhudiblu_PPA_v0panPan3
BTBD8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1656,756,682 - 56,849,849 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl656,698,320 - 56,900,173 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha659,460,913 - 59,555,751 (-)NCBI
ROS_Cfam_1.0657,139,502 - 57,232,357 (-)NCBI
UMICH_Zoey_3.1656,813,063 - 56,909,419 (-)NCBI
UNSW_CanFamBas_1.0656,791,209 - 56,885,794 (-)NCBI
UU_Cfam_GSD_1.0657,252,135 - 57,348,507 (-)NCBI
Btbd8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058101,970,548 - 102,048,694 (+)NCBI
SpeTri2.0NW_0049365376,899,271 - 6,977,420 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIAA1107
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4124,858,099 - 124,950,427 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14124,859,271 - 124,950,420 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
619619Rf4Renal disease susceptibility QTL 44.10.002total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14134403399Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14141333960Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14141333960Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14142766285Rat
71115Niddm15Non-insulin dependent diabetes mellitus QTL 154.8blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14222782512680613Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14222782519230541Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:70
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000037931, ENSRNOT00000061556
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 45
Low 3 41 56 40 19 40 8 11 29 35 41 11 8
Below cutoff 2 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_006250596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC106605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000037931   ⟹   ENSRNOP00000038747
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl143,284,089 - 3,300,200 (-)Ensembl
RefSeq Acc Id: XM_006250596   ⟹   XP_006250658
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2142,265,189 - 2,334,380 (-)NCBI
Rnor_6.0143,282,422 - 3,351,724 (-)NCBI
Rnor_5.0143,285,858 - 3,355,200 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250597   ⟹   XP_006250659
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2142,265,189 - 2,334,373 (-)NCBI
Rnor_6.0143,282,422 - 3,351,725 (-)NCBI
Rnor_5.0143,285,858 - 3,355,200 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599412   ⟹   XP_017454901
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2142,275,388 - 2,334,404 (-)NCBI
Rnor_6.0143,292,662 - 3,351,740 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092623   ⟹   XP_038948551
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2142,265,189 - 2,334,374 (-)NCBI
RefSeq Acc Id: XM_039092624   ⟹   XP_038948552
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2142,265,189 - 2,334,375 (-)NCBI
RefSeq Acc Id: XM_039092625   ⟹   XP_038948553
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2142,266,444 - 2,338,426 (-)NCBI
RefSeq Acc Id: XM_039092626   ⟹   XP_038948554
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2142,265,189 - 2,329,441 (-)NCBI
RefSeq Acc Id: XM_039092627   ⟹   XP_038948555
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2142,267,378 - 2,334,374 (-)NCBI
RefSeq Acc Id: XM_039092628   ⟹   XP_038948556
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2142,267,378 - 2,334,371 (-)NCBI
RefSeq Acc Id: XM_039092629   ⟹   XP_038948557
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2142,265,189 - 2,295,818 (-)NCBI
RefSeq Acc Id: XM_039092630   ⟹   XP_038948558
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2142,265,189 - 2,281,916 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_006250659   ⟸   XM_006250597
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006250658   ⟸   XM_006250596
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017454901   ⟸   XM_017599412
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: ENSRNOP00000038747   ⟸   ENSRNOT00000037931
RefSeq Acc Id: XP_038948552   ⟸   XM_039092624
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038948551   ⟸   XM_039092623
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038948554   ⟸   XM_039092626
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038948557   ⟸   XM_039092629
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038948558   ⟸   XM_039092630
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038948553   ⟸   XM_039092625
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038948555   ⟸   XM_039092627
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038948556   ⟸   XM_039092628
- Peptide Label: isoform X7
Protein Domains
DUF4596

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2321418 AgrOrtholog
Ensembl Genes ENSRNOG00000023446 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000038747 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037931 UniProtKB/TrEMBL
InterPro DUF4596 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KIAA1107 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 100364240 ENTREZGENE
PANTHER PTHR22427:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF4596 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Btbd8 PhenoGen
UniProt A0A452Q762_RAT UniProtKB/TrEMBL
  D4A0X3 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-03 Btbd8  BTB domain containing 8  Btbd8  BTB (POZ) domain containing 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 Btbd8  BTB (POZ) domain containing 8  LOC689994  similar to H43E16.1  Data Merged 737654 PROVISIONAL
2013-08-07 LOC100364240  BTB (POZ) domain containing 8-like  Btbd8  BTB (POZ) domain containing 8  Data Merged 737654 APPROVED
2013-08-07 Btbd8  BTB (POZ) domain containing 8  LOC100364240  BTB (POZ) domain containing 8-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100364240  BTB (POZ) domain containing 8-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-10-30 Btbd8  BTB (POZ) domain containing 8  LOC690003  similar to BTB (POZ) domain containing 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC689994  similar to H43E16.1  RGD1306921_predicted  similar to mKIAA1107 protein (predicted)  Data Merged 1643240 APPROVED
2006-11-19 LOC689994  similar to H43E16.1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC690003  similar to BTB (POZ) domain containing 8      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 RGD1306921_predicted  similar to mKIAA1107 protein (predicted)  LOC305122_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC305122_predicted  similar to mKIAA1107 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL