Gene: LOC100364500 (RT1 class I, locus CE11-like) Rattus norvegicus
Analyze
Symbol: LOC100364500
Name: RT1 class I, locus CE11-like
Description: ENCODES a protein that exhibits beta-2-microglobulin binding (ortholog); peptide antigen binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN antibacterial humoral response (ortholog); antigen processing and presentation (ortholog); antigen processing and presentation of endogenous peptide antigen via MHC class I (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); Genetic Predisposition to Disease (ortholog); FOUND IN cell surface (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum exit site (ortholog); INTERACTS WITH 17beta-estradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione (ortholog)
AGR Description: Predicted to have several functions, including T cell receptor binding activity, TAP binding activity, and beta-2-microglobulin binding activity; predicted to be involved in several processes, including positive regulation of T cell activation, regulation of leukocyte mediated immunity, and response to bacterium; predicted to localize to the MHC class I protein complex, cell surface, and cytoplasm; orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A), HLA-B (major histocompatibility complex, class I, B), and HLA-E (major histocompatibility complex, class I, E).
Merged Description: Predicted to have several functions, including T cell receptor binding activity, TAP binding activity, and beta-2-microglobulin binding activity; predicted to be involved in several processes, including positive regulation of T cell activation, regulation of leukocyte mediated immunity, and response to bacterium; predicted to localize to the MHC class I protein complex, cell surface, and cytoplasm; orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A), HLA-B (major histocompatibility complex, class I, B), and HLA-E (major histocompatibility complex, class I, E); INTERACTS WITH 17beta-estradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: class I histocompatibility antigen, Non-RT1.A alpha-1 chain; RT1 class I histocompatibility antigen, AA alpha chain
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0202,704,153 - 2,707,111 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0204,805,474 - 4,808,452 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on LOC100364500
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2320860
Created: 2010-05-05
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.