Ociad2 (OCIA domain containing 2) - Rat Genome Database

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Gene: Ociad2 (OCIA domain containing 2) Rattus norvegicus
Analyze
Symbol: Ociad2
Name: OCIA domain containing 2
RGD ID: 2319541
Description: Predicted to act upstream of or within response to bacterium. Predicted to be located in endosome. Orthologous to human OCIAD2 (OCIA domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100361733; OCIA domain-containing protein 2; rCG57079-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81435,225,291 - 35,243,306 (+)NCBIGRCr8
mRatBN7.21434,873,668 - 34,889,276 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1434,873,820 - 34,889,265 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1435,238,220 - 35,253,634 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01436,542,977 - 36,558,393 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01435,031,301 - 35,046,715 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01437,432,999 - 37,449,425 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1437,435,654 - 37,444,775 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01437,251,451 - 37,267,486 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41437,273,819 - 37,292,695 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1434,131,808 - 34,147,246 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
endosome  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12865426   PMID:14651853   PMID:23012479  


Genomics

Comparative Map Data
Ociad2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81435,225,291 - 35,243,306 (+)NCBIGRCr8
mRatBN7.21434,873,668 - 34,889,276 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1434,873,820 - 34,889,265 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1435,238,220 - 35,253,634 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01436,542,977 - 36,558,393 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01435,031,301 - 35,046,715 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01437,432,999 - 37,449,425 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1437,435,654 - 37,444,775 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01437,251,451 - 37,267,486 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41437,273,819 - 37,292,695 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1434,131,808 - 34,147,246 (+)NCBICelera
Cytogenetic Map14p11NCBI
OCIAD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38448,885,019 - 48,906,828 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl448,885,019 - 48,906,937 (-)EnsemblGRCh38hg38GRCh38
GRCh37448,887,036 - 48,908,845 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36448,582,162 - 48,603,572 (-)NCBINCBI36Build 36hg18NCBI36
Build 34448,728,334 - 48,749,733NCBI
Celera449,335,798 - 49,357,208 (-)NCBICelera
Cytogenetic Map4p11NCBI
HuRef448,207,197 - 48,228,623 (-)NCBIHuRef
CHM1_1448,886,556 - 48,907,964 (-)NCBICHM1_1
T2T-CHM13v2.0448,851,611 - 48,873,422 (-)NCBIT2T-CHM13v2.0
Ociad2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39573,479,541 - 73,496,290 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl573,479,542 - 73,498,371 (-)EnsemblGRCm39 Ensembl
GRCm38573,322,198 - 73,338,947 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl573,322,199 - 73,341,028 (-)EnsemblGRCm38mm10GRCm38
MGSCv37573,713,438 - 73,729,878 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36573,601,927 - 73,617,696 (-)NCBIMGSCv36mm8
Celera570,576,762 - 70,593,183 (-)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map538.54NCBI
Ociad2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544718,820,368 - 18,834,886 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544718,822,253 - 18,834,886 (+)NCBIChiLan1.0ChiLan1.0
OCIAD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2378,959,034 - 78,980,759 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1479,220,679 - 79,242,403 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0473,247,989 - 73,269,749 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1483,977,124 - 83,998,682 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl483,977,152 - 83,998,674 (+)Ensemblpanpan1.1panPan2
OCIAD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11344,639,044 - 44,653,481 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1344,641,089 - 44,663,295 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1344,593,454 - 44,609,072 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01345,243,748 - 45,259,372 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1345,241,753 - 45,259,348 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11344,919,214 - 44,934,855 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01344,453,866 - 44,469,480 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01345,333,187 - 45,348,796 (-)NCBIUU_Cfam_GSD_1.0
Ociad2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528531,463,363 - 31,483,293 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648214,815,570 - 14,834,263 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648214,817,008 - 14,834,454 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OCIAD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl838,772,714 - 38,793,216 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1838,771,281 - 38,793,511 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2840,880,338 - 41,028,600 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OCIAD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1271,361,361 - 1,378,234 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl271,361,261 - 1,378,229 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604747,348,028 - 47,364,890 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ociad2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476118,119,184 - 18,135,269 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476118,119,769 - 18,135,269 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ociad2
32 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:120
Count of miRNA genes:99
Interacting mature miRNAs:106
Transcripts:ENSRNOT00000002991
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
2324617Coatc2Coat color QTL 20.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)143076702539153750Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141759376142336881Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141863134542337007Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141762256142337007Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat

Markers in Region
AW557942  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21434,897,899 - 34,898,008 (+)MAPPERmRatBN7.2
Rnor_6.01437,458,072 - 37,458,180NCBIRnor6.0
Rnor_5.01437,276,504 - 37,276,612UniSTSRnor5.0
RGSC_v3.41437,301,354 - 37,301,462UniSTSRGSC3.4
Celera1434,156,165 - 34,156,273UniSTS
Cytogenetic Map14p11UniSTS
RH132629  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21434,897,876 - 34,898,067 (+)MAPPERmRatBN7.2
Rnor_6.01437,458,049 - 37,458,239NCBIRnor6.0
Rnor_5.01437,276,481 - 37,276,671UniSTSRnor5.0
RGSC_v3.41437,301,331 - 37,301,521UniSTSRGSC3.4
Celera1434,156,142 - 34,156,332UniSTS
Cytogenetic Map14p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 8 32 17 15 17 64 35 32 11
Low 35 25 24 4 24 8 9 10 9 8
Below cutoff 2

Sequence


RefSeq Acc Id: ENSRNOT00000002991   ⟹   ENSRNOP00000002991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1434,873,820 - 34,888,149 (+)Ensembl
Rnor_6.0 Ensembl1437,435,654 - 37,444,775 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103904   ⟹   ENSRNOP00000076969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1434,873,820 - 34,889,262 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114702   ⟹   ENSRNOP00000089923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1434,876,432 - 34,889,265 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118064   ⟹   ENSRNOP00000077425
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1434,873,820 - 34,889,265 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118089   ⟹   ENSRNOP00000083291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1434,873,831 - 34,889,246 (+)Ensembl
RefSeq Acc Id: NM_001271181   ⟹   NP_001258110
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,227,883 - 35,243,306 (+)NCBI
mRatBN7.21434,873,841 - 34,889,269 (+)NCBI
Rnor_6.01437,432,999 - 37,449,425 (+)NCBI
Rnor_5.01437,251,451 - 37,267,486 (+)NCBI
Celera1434,131,808 - 34,147,246 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039091553   ⟹   XP_038947481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,225,299 - 35,243,302 (+)NCBI
mRatBN7.21434,873,668 - 34,887,847 (+)NCBI
RefSeq Acc Id: XM_063272791   ⟹   XP_063128861
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,225,373 - 35,243,302 (+)NCBI
RefSeq Acc Id: XM_063272792   ⟹   XP_063128862
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,225,291 - 35,243,302 (+)NCBI
RefSeq Acc Id: XM_063272793   ⟹   XP_063128863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81435,230,474 - 35,243,302 (+)NCBI
RefSeq Acc Id: NP_001258110   ⟸   NM_001271181
- UniProtKB: A6JD38 (UniProtKB/TrEMBL),   A0A8I5ZV64 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000002991   ⟸   ENSRNOT00000002991
RefSeq Acc Id: XP_038947481   ⟸   XM_039091553
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000076969   ⟸   ENSRNOT00000103904
RefSeq Acc Id: ENSRNOP00000083291   ⟸   ENSRNOT00000118089
RefSeq Acc Id: ENSRNOP00000089923   ⟸   ENSRNOT00000114702
RefSeq Acc Id: ENSRNOP00000077425   ⟸   ENSRNOT00000118064
RefSeq Acc Id: XP_063128862   ⟸   XM_063272792
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063128861   ⟸   XM_063272791
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063128863   ⟸   XM_063272793
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AAT5 (UniProtKB/TrEMBL)
Protein Domains
OCIA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4Q4-F1-model_v2 AlphaFold D4A4Q4 1-132 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2319541 AgrOrtholog
BioCyc Gene G2FUF-15864 BioCyc
Ensembl Genes ENSRNOG00000002196 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002991.8 UniProtKB/TrEMBL
  ENSRNOT00000103904.1 UniProtKB/TrEMBL
  ENSRNOT00000114702.1 UniProtKB/TrEMBL
  ENSRNOT00000118064.1 UniProtKB/TrEMBL
  ENSRNOT00000118089 ENTREZGENE
  ENSRNOT00000118089.1 UniProtKB/TrEMBL
InterPro OCAD1/2 UniProtKB/TrEMBL
  OCIA UniProtKB/TrEMBL
KEGG Report rno:100361733 UniProtKB/TrEMBL
NCBI Gene 100361733 ENTREZGENE
PANTHER OCIA DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  PTHR13336 UniProtKB/TrEMBL
Pfam OCIA UniProtKB/TrEMBL
PhenoGen Ociad2 PhenoGen
RatGTEx ENSRNOG00000002196 RatGTEx
UniProt A0A8I5XVM7_RAT UniProtKB/TrEMBL
  A0A8I5YCD2_RAT UniProtKB/TrEMBL
  A0A8I5ZV64 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AAT5 ENTREZGENE, UniProtKB/TrEMBL
  A6JD38 ENTREZGENE, UniProtKB/TrEMBL
  D4A4Q4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-22 Ociad2  OCIA domain containing 2  LOC100361733  rCG57079-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100361733  rCG57079-like      Symbol and Name status set to provisional 70820 PROVISIONAL