Mir208b (microRNA 208b) - Rat Genome Database

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Gene: Mir208b (microRNA 208b) Mus musculus
Analyze
Symbol: Mir208b
Name: microRNA 208b
RGD ID: 2314107
MGI Page MGI
Description: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Acts upstream of or within several processes, including cardiac muscle hypertrophy in response to stress; cellular response to trichostatin A; and histone H3-K27 methylation. Located in cytosol and nucleus. Is expressed in heart and soleus. Orthologous to human MIR208B (microRNA 208b).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-208b; Mirn2; Mirn208b
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,213,157 - 55,213,233 (-)NCBIGRCm39mm39
GRCm39 Ensembl1455,213,157 - 55,213,233 (-)Ensembl
GRCm381454,975,700 - 54,975,776 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,975,700 - 54,975,776 (-)EnsemblGRCm38mm10GRCm38
MGSCv371455,594,537 - 55,594,613 (-)NCBIGRCm37mm9NCBIm37
Celera1452,781,639 - 52,781,715 (-)NCBICelera
Cytogenetic Map14C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IDA)
nucleus  (IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:16381832   PMID:16954537   PMID:17604727   PMID:17989215   PMID:18256189   PMID:19188439   PMID:19726871   PMID:19922871   PMID:20413612   PMID:21037258   PMID:21267068   PMID:22374132  
PMID:23676496   PMID:24137001   PMID:28105427   PMID:30696455  


Genomics

Comparative Map Data
Mir208b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,213,157 - 55,213,233 (-)NCBIGRCm39mm39
GRCm39 Ensembl1455,213,157 - 55,213,233 (-)Ensembl
GRCm381454,975,700 - 54,975,776 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,975,700 - 54,975,776 (-)EnsemblGRCm38mm10GRCm38
MGSCv371455,594,537 - 55,594,613 (-)NCBIGRCm37mm9NCBIm37
Celera1452,781,639 - 52,781,715 (-)NCBICelera
Cytogenetic Map14C3NCBI
MIR208B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1423,417,987 - 23,418,063 (-)EnsemblGRCh38hg38GRCh38
GRCh381423,417,987 - 23,418,063 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371423,887,196 - 23,887,272 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,957,035 - 22,957,111 (-)NCBINCBI36hg18NCBI36
Celera143,749,891 - 3,749,967 (-)NCBI
Cytogenetic Map14q11.2NCBI
HuRef144,003,632 - 4,003,708 (-)NCBIHuRef
CHM1_11423,885,868 - 23,885,944 (-)NCBICHM1_1
Mir208b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21528,451,638 - 28,451,749 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1528,451,638 - 28,451,749 (-)Ensembl
Rnor_6.01533,639,510 - 33,639,621 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,639,510 - 33,639,621 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,526,109 - 37,526,220 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1528,029,311 - 28,029,422 (-)NCBICelera
Cytogenetic Map15p13NCBI
MIR208B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,665,163 - 3,665,236 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,665,163 - 3,665,236 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.083,772,895 - 3,772,968 (-)NCBI
UMICH_Zoey_3.183,464,425 - 3,464,498 (-)NCBI
UNSW_CanFamBas_1.083,525,897 - 3,525,970 (-)NCBI
UU_Cfam_GSD_1.083,787,921 - 3,787,994 (-)NCBI
MIR208B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,667,786 - 75,667,865 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,667,786 - 75,667,865 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,071,323 - 81,071,402 (-)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420837405121032392Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142101238271648361Mouse
14746973Manh76_mmandible shape 76 (mouse)142256526056565260Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492582457942312Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142820000060900000Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142975953763759676Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143009779364097924Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143009779364097924Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143060000087700000Mouse
27226737Metcl12_mmetatarsal-calcaneal length 12, 10 week (mouse)143350000059200000Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143532384068548287Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143719272871192863Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4009986274099862Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144272496776725144Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144272496776725144Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144279982176799969Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144282839876828596Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144282839876828596Mouse
4141484Hcbip1_mhexachlorobenzene induced porphyria 1 (mouse)Not determined4709779359725144Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144921797683218107Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145204453586044676Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145352385687524089Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145370000087700000Mouse

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:15662
Count of gene targets:7031
Count of transcripts:11355
Interacting mature miRNAs:mmu-miR-208b-3p, mmu-miR-208b-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000104735
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1455,213,157 - 55,213,233 (-)Ensembl
GRCm38.p6 Ensembl1454,975,700 - 54,975,776 (-)Ensembl
RefSeq Acc Id: NR_030607
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391455,213,157 - 55,213,233 (-)NCBI
GRCm381454,975,700 - 54,975,776 (-)ENTREZGENE
MGSCv371455,594,537 - 55,594,613 (-)RGD
Celera1452,781,639 - 52,781,715 (-)RGD
cM Map14 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3718461 AgrOrtholog
Ensembl Genes ENSMUSG00000077928 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000104735 ENTREZGENE
MGD MGI:3718461 ENTREZGENE
miRBase MI0005552 ENTREZGENE
NCBI Gene 100124433 ENTREZGENE
PhenoGen Mir208b PhenoGen
RNAcentral URS000034979B RNACentral
  URS0000508226 RNACentral
  URS000075BCD9 RNACentral