Timd5 (T cell immunoglobulin and mucin domain containing 5) - Rat Genome Database

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Gene: Timd5 (T cell immunoglobulin and mucin domain containing 5) Mus musculus
Analyze
No known orthologs.
Symbol: Timd5 (Ensembl: Gm12169)
Name: T cell immunoglobulin and mucin domain containing 5 (Ensembl:predicted gene 12169)
RGD ID: 2313703
MGI Page MGI
Description: Predicted to enable phosphatidylserine binding activity and virus receptor activity. Predicted to be involved in phagocytosis, engulfment and positive regulation of mast cell activation. Predicted to be located in motile cilium. Predicted to be active in cell surface. Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C80168; expressed sequence C80168; Gm12169; Hepatitis A virus cellular receptor 1 homolog-like; hepatitis A virus cellular receptor 1-like; hypothetical protein LOC210535; uncharacterized protein LOC210535
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391146,415,078 - 46,428,983 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1146,415,039 - 46,428,983 (+)EnsemblGRCm39 Ensembl
GRCm381146,524,251 - 46,538,156 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1146,524,212 - 46,538,156 (+)EnsemblGRCm38mm10GRCm38
MGSCv371146,337,753 - 46,351,658 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361146,367,674 - 46,381,579 (+)NCBIMGSCv36mm8
Celera1151,104,375 - 51,118,515 (+)NCBICelera
Cytogenetic Map11B1.1NCBI
cM Map1127.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10725249   PMID:10922068   PMID:21267068   PMID:21677750   PMID:21873635  


Genomics

Variants

.
Variants in Timd5
424 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:72
Interacting mature miRNAs:74
Transcripts:ENSMUST00000109228
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112719805750636094Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112719805750636094Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112719805750636094Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112719805750636094Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112719805750636094Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114277262654081064Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse

Markers in Region
RH126819  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381146,537,919 - 46,538,149UniSTSGRCm38
MGSCv371146,351,421 - 46,351,651UniSTSGRCm37
Celera1151,118,278 - 51,118,508UniSTS
Cytogenetic Map11B1.1UniSTS
Whitehead/MRC_RH11621.06UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000109228   ⟹   ENSMUSP00000104851
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1146,415,039 - 46,428,983 (+)Ensembl
GRCm38.p6 Ensembl1146,524,212 - 46,538,156 (+)Ensembl
RefSeq Acc Id: NM_001163357   ⟹   NP_001156829
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391146,415,078 - 46,428,983 (+)NCBI
GRCm381146,524,251 - 46,538,156 (+)ENTREZGENE
MGSCv371146,337,753 - 46,351,658 (+)RGD
Celera1151,104,375 - 51,118,515 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001156829 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL33812 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000104851
  ENSMUSP00000104851.2
RefSeq Acc Id: NP_001156829   ⟸   NM_001163357
- Peptide Label: precursor
- UniProtKB: F2Z474 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000104851   ⟸   ENSMUST00000109228
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F2Z474-F1-model_v2 AlphaFold F2Z474 1-250 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3650838 AgrOrtholog
Ensembl Genes ENSMUSG00000078924 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000109228 ENTREZGENE
  ENSMUST00000109228.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
MGD MGI:3650838 ENTREZGENE
NCBI Gene 210535 ENTREZGENE
PANTHER GENE 12169-RELATED UniProtKB/TrEMBL
  HEPATITIS A VIRUS CELLULAR RECEPTOR 1 HOMOLOG UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PhenoGen Timd5 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt F2Z474 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-21 Timd5  T cell immunoglobulin and mucin domain containing 5  Gm12169  predicted gene 12169  Symbol and/or name updated 27372883 PROVISIONAL
2016-03-16 Gm12169  predicted gene 12169  C80168  expressed sequence C80168  Data merged from RGD:1612516 737654 PROVISIONAL