MIR1237 (microRNA 1237) - Rat Genome Database

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Gene: MIR1237 (microRNA 1237) Homo sapiens
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Symbol: MIR1237
Name: microRNA 1237
RGD ID: 2312887
HGNC Page HGNC
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: hsa-mir-1237; MIRN1237
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1164,368,602 - 64,368,703 (+)EnsemblGRCh38hg38GRCh38
GRCh381164,368,602 - 64,368,703 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371164,136,074 - 64,136,175 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera1161,462,074 - 61,462,175 (+)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1160,463,850 - 60,463,951 (+)NCBIHuRef
CHM1_11164,019,090 - 64,019,191 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16381832   PMID:17964270   PMID:25850393   PMID:26043902   PMID:28930610  


Genomics

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
ZNF106hsa-miR-1237-3pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248

Predicted Targets
Summary Value
Count of predictions:96960
Count of gene targets:25609
Count of transcripts:73585
Interacting mature miRNAs:hsa-miR-1237-3p, hsa-miR-1237-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Microtar, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium 1
Low 32 42 23 1 24 57 20 103 1 65 41 1 9 43
Below cutoff 119 125 59 22 94 10 155 107 213 10 98 48 12 62 101

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_031602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AP003774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000408346
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1164,368,602 - 64,368,703 (+)Ensembl
RefSeq Acc Id: NR_031602
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381164,368,602 - 64,368,703 (+)NCBI
GRCh371164,136,074 - 64,136,175 (+)RGD
Celera1161,462,074 - 61,462,175 (+)RGD
HuRef1160,463,850 - 60,463,951 (+)RGD
CHM1_11164,019,090 - 64,019,191 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC MIR1237 COSMIC
Ensembl Genes ENSG00000221273 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000408346 ENTREZGENE
GTEx ENSG00000221273 GTEx
HGNC ID HGNC:33927 ENTREZGENE
Human Proteome Map MIR1237 Human Proteome Map
miRBase MI0006327 ENTREZGENE
NCBI Gene 100302280 ENTREZGENE
PharmGKB PA164722377 PharmGKB
RNAcentral URS00003E1F0B RNACentral
  URS000063ACDB RNACentral
  URS000075A763 RNACentral