ZNF252P-AS1 (ZNF252P antisense RNA 1) - Rat Genome Database

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Gene: ZNF252P-AS1 (ZNF252P antisense RNA 1) Homo sapiens
Analyze
Symbol: ZNF252P-AS1
Name: ZNF252P antisense RNA 1
RGD ID: 2303889
HGNC Page HGNC
Description: INTERACTS WITH folic acid
Type: ncrna
RefSeq Status: VALIDATED
Also known as: C8orf77; MGC141859
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8145,002,811 - 145,006,046 (+)EnsemblGRCh38hg38GRCh38
GRCh388145,002,811 - 145,006,046 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378146,228,197 - 146,231,432 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368146,199,177 - 146,231,895 (+)NCBINCBI36hg18NCBI36
Celera8142,405,233 - 142,408,468 (+)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8141,343,945 - 141,347,180 (+)NCBIHuRef
CHM1_18146,266,131 - 146,269,366 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
folic acid  (EXP)

References
Additional References at PubMed
PMID:12477932   PMID:14702039  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:64
Count of miRNA genes:64
Interacting mature miRNAs:64
Transcripts:ENST00000527067
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 25
Low 1417 718 1234 197 878 89 921 496 2314 238 1215 1065 116 210 760 2
Below cutoff 1007 2234 459 395 1016 345 3324 1636 1393 178 203 531 54 970 1956 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000527067
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8145,002,811 - 145,006,046 (+)Ensembl
RefSeq Acc Id: NR_026974
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388145,002,811 - 145,006,046 (+)NCBI
GRCh378146,228,197 - 146,231,432 (+)RGD
Celera8142,405,233 - 142,408,468 (+)RGD
HuRef8141,343,945 - 141,347,180 (+)ENTREZGENE
CHM1_18146,266,131 - 146,269,366 (+)NCBI
Sequence:
Protein Sequences
GenBank Protein BAC03974 (Get FASTA)   NCBI Sequence Viewer  
  Q0IIN9 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences

Promoters
RGD ID:15096294
Promoter ID:EPDNEWNC_H1118
Type:initiation region
Name:ZNF252P-AS1_1
Description:ZNF252P antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27821]
SO ACC ID:SO:0000170
Source:EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388145,002,797 - 145,002,857EPDNEWNC
RGD ID:6806555
Promoter ID:HG_KWN:62383
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NR_026974
Position:
Human AssemblyChrPosition (strand)Source
Build 368146,198,116 - 146,199,267 (+)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 8q24.3(chr8:144925972-145054634)x1 copy number loss See cases [RCV000133727] Chr8:144925972..145054634 [GRCh38]
Chr8:146151358..146280020 [GRCh37]
Chr8:146122162..146250824 [NCBI36]
Chr8:8q24.3
benign
GRCh38/hg38 8q22.1-24.3(chr8:94682154-145068656)x3 copy number gain See cases [RCV000134353] Chr8:94682154..145068656 [GRCh38]
Chr8:95694382..146294042 [GRCh37]
Chr8:95763558..146264846 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:144997177-145010034)x1 copy number loss See cases [RCV000134094] Chr8:144997177..145010034 [GRCh38]
Chr8:146222563..146235420 [GRCh37]
Chr8:146193367..146206224 [NCBI36]
Chr8:8q24.3
benign|likely benign|conflicting data from submitters
GRCh38/hg38 8q24.3(chr8:144992787-145049504)x1 copy number loss See cases [RCV000134858] Chr8:144992787..145049504 [GRCh38]
Chr8:146218173..146274890 [GRCh37]
Chr8:146188977..146245694 [NCBI36]
Chr8:8q24.3
benign
GRCh38/hg38 8q24.22-24.3(chr8:130639182-145068712)x3 copy number gain See cases [RCV000137644] Chr8:130639182..145068712 [GRCh38]
Chr8:131651428..146294098 [GRCh37]
Chr8:131720610..146264902 [NCBI36]
Chr8:8q24.22-24.3
pathogenic|conflicting data from submitters
GRCh38/hg38 8q24.3(chr8:139236824-145068712)x3 copy number gain See cases [RCV000137466] Chr8:139236824..145068712 [GRCh38]
Chr8:140249067..146294098 [GRCh37]
Chr8:140318249..146264902 [NCBI36]
Chr8:8q24.3
likely pathogenic
GRCh38/hg38 8q24.3(chr8:139004218-145049449)x3 copy number gain See cases [RCV000137340] Chr8:139004218..145049449 [GRCh38]
Chr8:140016461..146274835 [GRCh37]
Chr8:140085643..146245639 [NCBI36]
Chr8:8q24.3
likely pathogenic
GRCh38/hg38 8q24.13-24.3(chr8:124498498-145068712)x3 copy number gain See cases [RCV000137346] Chr8:124498498..145068712 [GRCh38]
Chr8:125510739..146294098 [GRCh37]
Chr8:125579920..146264902 [NCBI36]
Chr8:8q24.13-24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:144935653-145049449)x3 copy number gain See cases [RCV000137226] Chr8:144935653..145049449 [GRCh38]
Chr8:146161039..146274835 [GRCh37]
Chr8:146131843..146245639 [NCBI36]
Chr8:8q24.3
benign
GRCh38/hg38 8p23.3-q24.3(chr8:241605-145054781)x3 copy number gain See cases [RCV000138643] Chr8:241605..145054781 [GRCh38]
Chr8:191605..146280167 [GRCh37]
Chr8:181605..146250971 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.3-24.3(chr8:87931152-145068712)x3 copy number gain See cases [RCV000138551] Chr8:87931152..145068712 [GRCh38]
Chr8:88943380..146294098 [GRCh37]
Chr8:89012496..146264902 [NCBI36]
Chr8:8q21.3-24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:144992787-145054781)x1 copy number loss See cases [RCV000139109] Chr8:144992787..145054781 [GRCh38]
Chr8:146218173..146280167 [GRCh37]
Chr8:146188977..146250971 [NCBI36]
Chr8:8q24.3
likely benign
GRCh38/hg38 8q21.13-24.3(chr8:77480050-145068712)x3 copy number gain See cases [RCV000139036] Chr8:77480050..145068712 [GRCh38]
Chr8:78392286..146294098 [GRCh37]
Chr8:78554841..146264902 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:97382873-145070385)x3 copy number gain See cases [RCV000140447] Chr8:97382873..145070385 [GRCh38]
Chr8:98395101..146295771 [GRCh37]
Chr8:98464277..146266575 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:144925972-145010039)x3 copy number gain See cases [RCV000140856] Chr8:144925972..145010039 [GRCh38]
Chr8:146151358..146235425 [GRCh37]
Chr8:146122162..146206229 [NCBI36]
Chr8:8q24.3
likely benign
GRCh38/hg38 8p23.3-q24.3(chr8:208048-145070385)x3 copy number gain See cases [RCV000141808] Chr8:208048..145070385 [GRCh38]
Chr8:158048..146295771 [GRCh37]
Chr8:148048..146266575 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:100867343-145070385)x3 copy number gain See cases [RCV000141694] Chr8:100867343..145070385 [GRCh38]
Chr8:101879571..146295771 [GRCh37]
Chr8:101948747..146266575 [NCBI36]
Chr8:8q22.3-24.3
pathogenic
GRCh38/hg38 8p21.3-q24.3(chr8:21291522-145070385)x3 copy number gain See cases [RCV000142021] Chr8:21291522..145070385 [GRCh38]
Chr8:21149033..146295771 [GRCh37]
Chr8:21193313..146266575 [NCBI36]
Chr8:8p21.3-q24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:103306336-145068712)x3 copy number gain See cases [RCV000142810] Chr8:103306336..145068712 [GRCh38]
Chr8:104318564..146294098 [GRCh37]
Chr8:104387740..146264902 [NCBI36]
Chr8:8q22.3-24.3
pathogenic|likely pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:226452-145068712)x3 copy number gain See cases [RCV000142858] Chr8:226452..145068712 [GRCh38]
Chr8:176452..146294098 [GRCh37]
Chr8:166452..146264902 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:78614077-145054634)x3 copy number gain See cases [RCV000142597] Chr8:78614077..145054634 [GRCh38]
Chr8:79526312..146280020 [GRCh37]
Chr8:79688867..146250824 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000148092] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.2-24.3(chr8:85765999-145070385)x3 copy number gain See cases [RCV000143659] Chr8:85765999..145070385 [GRCh38]
Chr8:86778228..146295771 [GRCh37]
Chr8:86863079..146266575 [NCBI36]
Chr8:8q21.2-24.3
pathogenic
GRCh38/hg38 8q24.13-24.3(chr8:124514090-145054634)x3 copy number gain See cases [RCV000148117] Chr8:124514090..145054634 [GRCh38]
Chr8:125526331..146280020 [GRCh37]
Chr8:125595512..146250824 [NCBI36]
Chr8:8q24.13-24.3
pathogenic
GRCh38/hg38 8q24.21-24.3(chr8:128220912-145049449)x3 copy number gain See cases [RCV000050830] Chr8:128220912..145049449 [GRCh38]
Chr8:129233158..146274835 [GRCh37]
Chr8:129302340..146245639 [NCBI36]
Chr8:8q24.21-24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:144992787-145054634)x1 copy number loss See cases [RCV000050610] Chr8:144992787..145054634 [GRCh38]
Chr8:146218173..146280020 [GRCh37]
Chr8:146188977..146250824 [NCBI36]
Chr8:8q24.3
uncertain significance
GRCh38/hg38 8q23.3-24.3(chr8:113580402-145054634)x3 copy number gain See cases [RCV000050638] Chr8:113580402..145054634 [GRCh38]
Chr8:114592631..146280020 [GRCh37]
Chr8:114661807..146250824 [NCBI36]
Chr8:8q23.3-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:144913443-145076819)x1 copy number loss See cases [RCV000052822] Chr8:144913443..145076819 [GRCh38]
Chr8:146138828..146302205 [GRCh37]
Chr8:146109632..146273009 [NCBI36]
Chr8:8q24.3
uncertain significance
GRCh38/hg38 8q22.1-24.3(chr8:95606052-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|See cases [RCV000053677] Chr8:95606052..145054775 [GRCh38]
Chr8:96618280..146280161 [GRCh37]
Chr8:96687456..146250965 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q24.13-24.3(chr8:124514090-145054634)x3 copy number gain See cases [RCV000053678] Chr8:124514090..145054634 [GRCh38]
Chr8:125526331..146280020 [GRCh37]
Chr8:125595512..146250824 [NCBI36]
Chr8:8q24.13-24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:139447227-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053701]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053701]|See cases [RCV000053701] Chr8:139447227..145054775 [GRCh38]
Chr8:140459470..146280161 [GRCh37]
Chr8:140528652..146250965 [NCBI36]
Chr8:8q24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:144002671-145054634)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053702]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053702]|See cases [RCV000053702] Chr8:144002671..145054634 [GRCh38]
Chr8:145076839..146280020 [GRCh37]
Chr8:145148827..146250824 [NCBI36]
Chr8:8q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000053602] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:244417-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|See cases [RCV000053604] Chr8:244417..145054775 [GRCh38]
Chr8:194417..146280161 [GRCh37]
Chr8:184417..146250965 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q24.3(chr8:144002471-145054775)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054311]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054311]|See cases [RCV000054311] Chr8:144002471..145054775 [GRCh38]
Chr8:145076639..146280161 [GRCh37]
Chr8:145148627..146250965 [NCBI36]
Chr8:8q24.3
pathogenic

Additional Information

Database Acc Id Source(s)
COSMIC ZNF252P-AS1 COSMIC
Ensembl Genes ENSG00000255559 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000527067 ENTREZGENE
GTEx ENSG00000255559 GTEx
HGNC ID HGNC:27821 ENTREZGENE
Human Proteome Map ZNF252P-AS1 Human Proteome Map
NCBI Gene 286103 ENTREZGENE
PharmGKB PA142672340 PharmGKB
RNAcentral URS000075D0B3 RNACentral
UniProt Q0IIN9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q8NAE8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-21 ZNF252P-AS1  ZNF252P antisense RNA 1  ZNF252P-AS1  ZNF252P antisense RNA 1 (non-protein coding)  Symbol and/or name change 5135510 APPROVED
2012-05-08 ZNF252P-AS1  ZNF252P antisense RNA 1 (non-protein coding)  C8orf77  chromosome 8 open reading frame 77  Symbol and/or name change 5135510 APPROVED