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Gene: PWRN1 (Prader-Willi region non-protein coding RNA 1) Homo sapiens
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Symbol: PWRN1
Name: Prader-Willi region non-protein coding RNA 1
Description: This gene is located in the Prader-Willi syndrome (PWS) region of chromosome 15, which is known to undergo imprinting. The transcript is believed to be non-coding. It is bi-allelically expressed in testis and kidney, but mono-allelically expressed from the paternal allele in brain. This gene is poly-adenylated and is known to undergo alternative splicing. Transcript variants may represent part of a complex imprinting center-SNURF-SNRPN transcription unit. The contribution of this gene to the PWS phenotype is unknown, but it has been suggested that it may play a role in establishing paternal imprinting in the PWS region, perhaps by maintaining the paternal allele in an open chromatin configuration. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: REVIEWED
Also known as: FLJ25418; NCRNA00198
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381524,558,157 - 24,587,780 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371524,803,304 - 24,832,927 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361524,803,304 - 24,832,927 (+)NCBINCBI36hg18NCBI36
Celera152,963,214 - 2,992,602 (+)NCBI
Cytogenetic Map15q11.2NCBI
HuRef152,939,244 - 2,968,837 (+)NCBIHuRef
CHM1_11524,752,887 - 24,782,722 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Clinical Variants

Additional Information

External Database Links
 
More on PWRN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2303844
Created: 2009-02-27
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.