Mup18 (major urinary protein 18) - Rat Genome Database

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Gene: Mup18 (major urinary protein 18) Mus musculus
Analyze
Symbol: Mup18
Name: major urinary protein 18
RGD ID: 2302848
MGI Page MGI
Description: Predicted to enable odorant binding activity. Predicted to be active in extracellular space.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 100039228; alpha-2U-globulin; Gm12561; group 1, BS6; major urinary protein 16; Major urinary protein 6; major urinary protein 9; MUP 6; Mup16; Mup6; Mup9; novel member of the major urinary protein (Mup) gene family
RGD Orthologs
Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39461,588,414 - 61,592,389 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl461,588,414 - 61,592,373 (-)EnsemblGRCm39 Ensembl
GRCm38461,670,177 - 61,674,132 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl461,670,177 - 61,674,136 (-)EnsemblGRCm38mm10GRCm38
MGSCv37461,320,589 - 61,335,189 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36461,331,212 - 61,335,189 (-)NCBIMGSCv36mm8
Cytogenetic Map4B3NCBI
cM Map432.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:1279439   PMID:2824995   PMID:3004935   PMID:3858875   PMID:6329733   PMID:7107707   PMID:7937138   PMID:8065364   PMID:11316880   PMID:12477932   PMID:14871097   PMID:15489334  
PMID:16141072   PMID:18064011   PMID:18815613   PMID:21873635   PMID:30782214  


Genomics

Comparative Map Data
Mup18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39461,588,414 - 61,592,389 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl461,588,414 - 61,592,373 (-)EnsemblGRCm39 Ensembl
GRCm38461,670,177 - 61,674,132 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl461,670,177 - 61,674,136 (-)EnsemblGRCm38mm10GRCm38
MGSCv37461,320,589 - 61,335,189 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36461,331,212 - 61,335,189 (-)NCBIMGSCv36mm8
Cytogenetic Map4B3NCBI
cM Map432.89NCBI
Mup18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8579,783,258 - 79,861,088 (-)NCBIGRCr8
mRatBN7.2574,986,813 - 74,990,071 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl574,842,319 - 75,061,474 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0577,339,109 - 77,342,318 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl577,338,853 - 77,342,299 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0581,442,881 - 81,471,856 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4579,016,222 - 79,018,502 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera573,788,414 - 73,790,329 (-)NCBICelera
Cytogenetic Map5q24NCBI

Variants

.
Variants in Mup18
49 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:105
Count of miRNA genes:100
Interacting mature miRNAs:101
Transcripts:ENSMUST00000098040
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124055180Mouse
13524838Hbasrq1a_mhabituation of the acoustic startle response QTL 1a (mouse)45447158988471589Mouse
1301786Bpq3_mblood pressure QTL 3 (mouse)Not determined44240224076402381Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
1301213Lgth3_mbody length 3 (mouse)Not determined45010026284100408Mouse
13524841Hbasrq1_mhabituation of the acoustic startle response QTL 1 (mouse)45447158988471589Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763283678Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
12879977Bod2_mbone length and organs 2 (mouse)44628353180283678Mouse
1300966Pabr2_mplasma apolipoprotein B (human) regulator 2 (mouse)Not determined446332646105801860Mouse
1301995Lprm1_mlymphoproliferation modifier 1 (mouse)Not determined45010026284100408Mouse
1301033Abbp2_mA/J and C57BL/6 blood pressure 2 (mouse)Not determined45355083993763305Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1301941Mmtg1_mmodifier of mammary tumor growth 1 (mouse)Not determined44565844283099157Mouse
10043964Obq26_mobesity QTL 26 (mouse)Not determined45904725193047251Mouse
10043880Adip23_madiposity 23 (mouse)Not determined44628353180283678Mouse
10449022Aanq1_maristolochic acid nephrotoxicity QTL 1 (mouse)44660382680603826Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
10412178Habiir2_mhyperoxic acute lung injury imprinted region 2 (mouse)Not determined43945212663283678Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
13207572Spir2_mStreptococcus pneumoniae infection resistance 2 (mouse)45068279588510637Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
1558948Ath8_matherosclerosis 8 (mouse)Not determined445658442105156995Mouse
1301190Cd4ts2_mCD4 T cell subset 2 (mouse)Not determined46014527794145424Mouse
1357443Lhyp_mlung hyperpermeability (mouse)Not determined46045401166764818Mouse
11532688Mh_mmodifier of hemostasis (mouse)44830477582304775Mouse
27095934Ulnl2_mulna length 2, 5 week (mouse)45770000094788237Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108357197Mouse
25314308Mlh1fc1_mMLH1 foci count 1 (mouse)44850000076918237Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
26884434Zlq1_mzygomatic length QTL 1, 5 week (mouse)453700000103257197Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1357507Synch2_msynechia 2 (mouse)Not determined46014527794145424Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000098040   ⟹   ENSMUSP00000095648
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl461,588,414 - 61,592,373 (-)Ensembl
GRCm38.p6 Ensembl461,670,177 - 61,674,136 (-)Ensembl
RefSeq Acc Id: NM_001199333   ⟹   NP_001186262
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39461,588,414 - 61,592,331 (-)NCBI
GRCm38461,670,177 - 61,674,094 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006537515   ⟹   XP_006537578
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39461,588,414 - 61,592,389 (-)NCBI
GRCm38461,670,177 - 61,674,132 (-)NCBI
Sequence:
RefSeq Acc Id: XP_006537578   ⟸   XM_006537515
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001186262   ⟸   NM_001199333
- Peptide Label: precursor
- UniProtKB: P04938 (UniProtKB/Swiss-Prot),   A2BIM8 (UniProtKB/TrEMBL),   Q9CXU6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000095648   ⟸   ENSMUST00000098040

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2BIM8-F1-model_v2 AlphaFold A2BIM8 1-181 view protein structure
AF-P04938-F1-model_v2 AlphaFold P04938 1-181 view protein structure

Promoters
RGD ID:6883590
Promoter ID:EPDNEW_M5237
Type:initiation region
Name:Mup18_1
Description:Mus musculus major urinary protein 18 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38461,674,089 - 61,674,149EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3705220 AgrOrtholog
Ensembl Genes ENSMUSG00000073834 UniProtKB/Swiss-Prot
  ENSMUSG00000078674 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000098040 ENTREZGENE
  ENSMUST00000098040.4 UniProtKB/Swiss-Prot
  ENSMUST00000098046.10 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.128.20 UniProtKB/Swiss-Prot
InterPro Calycin UniProtKB/Swiss-Prot
  Lipocalin UniProtKB/Swiss-Prot
  Lipocalin_CS UniProtKB/Swiss-Prot
  Lipocln_cytosolic_FA-bd_dom UniProtKB/Swiss-Prot
  Maj_urinary UniProtKB/Swiss-Prot
MGD MGI:3705220 ENTREZGENE
NCBI Gene Mup18 ENTREZGENE
PANTHER MAJOR URINARY PROTEIN 1-RELATED UniProtKB/Swiss-Prot
  PTHR11430 UniProtKB/Swiss-Prot
Pfam Lipocalin UniProtKB/Swiss-Prot
PhenoGen Mup18 PhenoGen
PRINTS LIPOCALIN UniProtKB/Swiss-Prot
  MAJORURINARY UniProtKB/Swiss-Prot
PROSITE LIPOCALIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50814 UniProtKB/Swiss-Prot
UniProt A2BIM8 ENTREZGENE
  MUP11_MOUSE UniProtKB/Swiss-Prot
  MUP18_MOUSE UniProtKB/Swiss-Prot
  P04938 ENTREZGENE
  Q9CXU6 ENTREZGENE