Dynlt2a2 (dynein light chain Tctex-type 2A2) - Rat Genome Database

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Gene: Dynlt2a2 (dynein light chain Tctex-type 2A2) Mus musculus
Analyze
No known orthologs.
Symbol: Dynlt2a2
Name: dynein light chain Tctex-type 2A2
RGD ID: 2301796
MGI Page MGI
Description: Orthologous to human DYNLT2 (dynein light chain Tctex-type 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 100041639; dynein light chain Tctex-type 2; Dynlt2; Dynlt2b; Gm3448; LC2; T-complex testis-specific protein 2; T-complex testis-specific protein 3; t-complex-associated testis expressed 3-like; T-complex-associated testis-expressed protein 3; T-complex-associated testis-expressed protein 4; Tcte-3; Tcte3; TCTEX-2; TCTEX-4; Tctex1 domain-containing protein 3; Tctex1d3; Tctex2; Tctex4
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391715,216,045 - 15,230,446 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1715,216,078 - 15,230,444 (-)EnsemblGRCm39 Ensembl
GRCm381714,995,783 - 15,010,184 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1715,027,152 - 15,041,488 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1714,995,787 - 15,041,537 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1714,964,242 - 14,978,790 (-)EnsemblGRCm38mm10GRCm38
MGSCv371715,132,747 - 15,147,148 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361715,132,747 - 15,147,148 (-)NCBIMGSCv36mm8
Cytogenetic Map17A2NCBI
cM Map178.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Dynlt2a2
477 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:131
Count of miRNA genes:126
Interacting mature miRNAs:131
Transcripts:ENSMUST00000097399
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357452Vtbt18_mvertebral trabecular bone trait 18 (mouse)Not determined17120975022Mouse
1302196Myaa1_mmodifier of Yaa 1 (mouse)Not determined17120975022Mouse
1357902Obq19_mobesity QTL 19 (mouse)Not determined17125662076Mouse
12910982Pifs2_mpeptide-induced fatal syndrome 2 (mouse)17126189355Mouse
1357743Lith3_mlithogenic gene 3 (mouse)Not determined17126194456Mouse
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17127081639Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17127081639Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17129198453Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17129198453Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17129198453Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17131030170Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17397489026401133Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17485475227715939Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17787584329487423Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
4142507Obrq13_mobesity resistance QTL 13 (mouse)Not determined1219832925076769Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
1558807Ceat1_mchronic experimental autoimmune thyroiditis 1 (mouse)Not determined171263668226401133Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000040746   ⟹   ENSMUSP00000036704
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1715,247,416 - 15,261,750 (-)Ensembl
GRCm38.p6 Ensembl1715,027,154 - 15,041,488 (-)Ensembl
RefSeq Acc Id: ENSMUST00000097398   ⟹   ENSMUSP00000095010
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1715,247,414 - 15,261,701 (-)Ensembl
GRCm38.p6 Ensembl1715,027,152 - 15,041,439 (-)Ensembl
RefSeq Acc Id: ENSMUST00000097399   ⟹   ENSMUSP00000095011
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1715,184,504 - 15,199,052 (-)Ensembl
GRCm38.p6 Ensembl1714,964,242 - 14,978,790 (-)Ensembl
RefSeq Acc Id: ENSMUST00000097400   ⟹   ENSMUSP00000095012
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1715,216,049 - 15,261,799 (-)Ensembl
GRCm38.p6 Ensembl1714,995,787 - 15,041,537 (-)Ensembl
RefSeq Acc Id: ENSMUST00000179539   ⟹   ENSMUSP00000137218
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1715,216,078 - 15,230,444 (-)Ensembl
GRCm38.p6 Ensembl1714,995,816 - 15,010,182 (-)Ensembl
RefSeq Acc Id: ENSMUST00000231584   ⟹   ENSMUSP00000155901
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1715,184,504 - 15,198,955 (-)Ensembl
GRCm38.p6 Ensembl1714,964,242 - 14,978,693 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232173   ⟹   ENSMUSP00000156122
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1715,184,504 - 15,199,052 (-)Ensembl
GRCm38.p6 Ensembl1714,964,242 - 14,978,790 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232299   ⟹   ENSMUSP00000156126
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1715,228,179 - 15,230,431 (-)Ensembl
GRCm38.p6 Ensembl1715,007,917 - 15,010,169 (-)Ensembl
RefSeq Acc Id: NM_001123367   ⟹   NP_001116839
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391715,216,045 - 15,230,446 (-)NCBI
GRCm381714,995,783 - 15,010,184 (-)ENTREZGENE
MGSCv371715,132,747 - 15,147,148 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001360662   ⟹   NP_001347591
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391715,216,045 - 15,230,446 (-)NCBI
GRCm381714,995,783 - 15,010,184 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001116839   ⟸   NM_001123367
- Peptide Label: isoform 1
- UniProtKB: A0A0R4J284 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001347591   ⟸   NM_001360662
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000036704   ⟸   ENSMUST00000040746
RefSeq Acc Id: ENSMUSP00000155901   ⟸   ENSMUST00000231584
RefSeq Acc Id: ENSMUSP00000137218   ⟸   ENSMUST00000179539
RefSeq Acc Id: ENSMUSP00000156126   ⟸   ENSMUST00000232299
RefSeq Acc Id: ENSMUSP00000156122   ⟸   ENSMUST00000232173
RefSeq Acc Id: ENSMUSP00000095011   ⟸   ENSMUST00000097399
RefSeq Acc Id: ENSMUSP00000095010   ⟸   ENSMUST00000097398
RefSeq Acc Id: ENSMUSP00000095012   ⟸   ENSMUST00000097400

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P11985-F1-model_v2 AlphaFold P11985 1-191 view protein structure

Promoters
RGD ID:13674812
Promoter ID:EPDNEW_M21555
Type:initiation region
Name:Gm3417_1
Description:Mus musculus predicted gene 3417 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21556  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381715,010,162 - 15,010,222EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3809205 AgrOrtholog
Ensembl Genes ENSMUSG00000079707 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSMUSG00000079710 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSG00000116780 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000040746.8 UniProtKB/TrEMBL
  ENSMUST00000097398.12 UniProtKB/Swiss-Prot
  ENSMUST00000097399.6 UniProtKB/Swiss-Prot
  ENSMUST00000097400.5 UniProtKB/TrEMBL
  ENSMUST00000179539 ENTREZGENE
  ENSMUST00000179539.9 UniProtKB/TrEMBL
  ENSMUST00000231584.2 UniProtKB/Swiss-Prot
  ENSMUST00000232299.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1140.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Tctex-1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tctex-1-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:100041586 UniProtKB/Swiss-Prot
  mmu:100041639 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  mmu:21647 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:3809205 ENTREZGENE
NCBI Gene 100041639 ENTREZGENE
PANTHER DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR21255 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Tctex-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dynlt2a2 PhenoGen
UniProt A0A0R4J284 ENTREZGENE, UniProtKB/TrEMBL
  A0A338P777_MOUSE UniProtKB/TrEMBL
  TC1D3_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary P51806 UniProtKB/Swiss-Prot
  Q66L72 UniProtKB/Swiss-Prot
  Q7TN76 UniProtKB/Swiss-Prot
  Q9D9X4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-10-19 Dynlt2a2  dynein light chain Tctex-type 2A2  Dynlt2  dynein light chain Tctex-type 2  Symbol and/or name updated 27372883 PROVISIONAL
2020-10-12 Dynlt2  dynein light chain Tctex-type 2  Gm3448  predicted gene 3448  Symbol and/or name updated 27372883 PROVISIONAL