Ak9 (adenylate kinase 9) - Rat Genome Database

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Gene: Ak9 (adenylate kinase 9) Mus musculus
Analyze
Symbol: Ak9
Name: adenylate kinase 9
RGD ID: 2301662
MGI Page MGI
Description: Predicted to enable adenylate kinase activity and nucleoside diphosphate kinase activity. Predicted to be involved in nucleotide metabolic process. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be active in mitochondrion. Is expressed in brain; lung; and rib. Orthologous to human AK9 (adenylate kinase 9).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 633979; adenylate kinase domain containing 1; adenylate kinase domain containing 2; adenylate kinase domain-containing protein 1; Akd; Akd1; Akd2; Gm234; Gm7127; predicted gene 7127
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391041,179,433 - 41,309,565 (+)NCBIGRCm39mm39
GRCm39 Ensembl1041,179,976 - 41,310,530 (+)Ensembl
GRCm381041,303,432 - 41,433,569 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1041,303,980 - 41,434,534 (+)EnsemblGRCm38mm10GRCm38
MGSCv371041,036,053 - 41,153,094 (+)NCBIGRCm37mm9NCBIm37
MGSCv361041,044,897 - 41,170,476 (+)NCBImm8
Celera1042,210,788 - 42,327,936 (+)NCBICelera
Cytogenetic Map10B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,ISO)
mitochondrion  (IBA)
nuclear membrane  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Ak9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391041,179,433 - 41,309,565 (+)NCBIGRCm39mm39
GRCm39 Ensembl1041,179,976 - 41,310,530 (+)Ensembl
GRCm381041,303,432 - 41,433,569 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1041,303,980 - 41,434,534 (+)EnsemblGRCm38mm10GRCm38
MGSCv371041,036,053 - 41,153,094 (+)NCBIGRCm37mm9NCBIm37
MGSCv361041,044,897 - 41,170,476 (+)NCBImm8
Celera1042,210,788 - 42,327,936 (+)NCBICelera
Cytogenetic Map10B1NCBI
AK9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386109,492,855 - 109,691,202 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6109,492,855 - 109,691,217 (-)EnsemblGRCh38hg38GRCh38
GRCh376109,814,058 - 110,012,405 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366110,059,592 - 110,119,113 (-)NCBINCBI36hg18NCBI36
Build 346110,059,591 - 110,119,113NCBI
Celera6110,560,655 - 110,759,036 (-)NCBI
Cytogenetic Map6q21NCBI
HuRef6107,380,087 - 107,578,597 (-)NCBIHuRef
CHM1_16110,077,000 - 110,275,395 (-)NCBICHM1_1
Ak9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22044,724,494 - 44,941,135 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2044,724,496 - 44,941,136 (+)Ensembl
Rnor_6.02046,044,901 - 46,162,015 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2046,044,892 - 46,162,073 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02047,786,342 - 47,859,461 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42045,274,347 - 45,403,396 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2045,523,222 - 45,559,777 (+)NCBICelera
Celera2055,011,652 - 55,087,256 (-)NCBICelera
Cytogenetic Map20q12NCBI
Ak9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955402665 - 124,777 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955402704 - 128,521 (-)NCBIChiLan1.0ChiLan1.0
AK9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16111,344,563 - 111,539,932 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6111,344,834 - 111,539,932 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06107,296,088 - 107,495,623 (-)NCBIMhudiblu_PPA_v0panPan3
AK9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11266,381,215 - 66,508,559 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1266,389,190 - 66,500,273 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1266,200,889 - 66,328,259 (-)NCBI
ROS_Cfam_1.01267,273,574 - 67,393,506 (-)NCBI
UMICH_Zoey_3.11266,621,642 - 66,741,395 (-)NCBI
UNSW_CanFamBas_1.01266,462,926 - 66,590,946 (-)NCBI
UU_Cfam_GSD_1.01266,734,701 - 66,862,137 (-)NCBI
Ak9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946101,335,164 - 101,461,240 (-)NCBI
SpeTri2.0NW_0049365645,610,445 - 5,727,782 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AK9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1175,558,009 - 75,693,415 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2184,916,875 - 84,967,083 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AK9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11364,187,376 - 64,379,458 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1364,196,413 - 64,379,460 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604036,489,415 - 36,666,478 (+)NCBIVero_WHO_p1.0
Ak9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480530,647 - 163,314 (-)NCBIHetGla_female_1.0hetGla2


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208561Wght8_mweight 8 (mouse)10495000043875996Mouse
1302092Ath11_matherosclerosis 11 (mouse)Not determined10615194558693521Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
1558865Lith21_mlithogenic gene 21 (mouse)Not determined10852500342525126Mouse
1301448Pas11_mpulmonary adenoma susceptibility 11 (mouse)Not determined10989026443890391Mouse
1301129Alcp15_malcohol preference locus 15 (mouse)Not determined10989026443890391Mouse
1302133Alcp16_malcohol preference locus 16 (mouse)Not determined10989026443890391Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
10755518Chol16_mcholesterol 16 (mouse)101891504352915043Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102028318556031223Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102159119268091639Mouse
26884394Humsd3_mhumerus midshaft diameter 3, 10 week (mouse)102237589951076096Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
4142209Psrs1_mpsoriasis susceptibility 1 (mouse)Not determined102689026446720483Mouse
1300898Cfid_mcystic fibrosis intestinal distress (mouse)Not determined102972040363720483Mouse
10045632Heal16_mwound healing/regeneration 16 (mouse)Not determined103097449964974630Mouse
1357558Bmch4_mbone mechanical trait 4 (mouse)Not determined103157713665577284Mouse
27095920Pglq9_mpelvic girdle length QTL 9, 10 week (mouse)103377599670835830Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
21079434Bdym5_mbody mass QTL 5 (mouse)104054599654836096Mouse
4141070Ltgq1_mliver triglyceride QTL 1 (mouse)Not determined4123732675237326Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:529
Count of miRNA genes:384
Interacting mature miRNAs:419
Transcripts:ENSMUST00000173494, ENSMUST00000173517
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000173494   ⟹   ENSMUSP00000134177
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1041,179,976 - 41,310,530 (+)Ensembl
GRCm38.p6 Ensembl1041,303,980 - 41,434,534 (+)Ensembl
RefSeq Acc Id: NM_001370813   ⟹   NP_001357742
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391041,179,930 - 41,309,564 (+)NCBI
GRCm381041,303,934 - 41,433,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006512939   ⟹   XP_006513002
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391041,179,433 - 41,309,565 (+)NCBI
GRCm381041,303,432 - 41,433,569 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001357742 (Get FASTA)   NCBI Sequence Viewer  
  XP_006513002 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_006513002   ⟸   XM_006512939
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001357742   ⟸   NM_001370813
RefSeq Acc Id: ENSMUSP00000134177   ⟸   ENSMUST00000173494
Protein Domains
AAA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3UYQ4-F1-model_v2 AlphaFold G3UYQ4 1-1894 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685080 AgrOrtholog
Ensembl Genes ENSMUSG00000091415 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000134177 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000173494 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  Adenylat/UMP-CMP_kin UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
MGD MGI:2685080 ENTREZGENE
NCBI Gene 633979 ENTREZGENE
PANTHER PTHR23359 UniProtKB/TrEMBL
PhenoGen Ak9 PhenoGen
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt G3UYQ4_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Ak9  adenylate kinase 9  Akd2  adenylate kinase domain containing 2  Data Merged 737654 PROVISIONAL
2014-09-08 Ak9  adenylate kinase 9  Gm7127  predicted gene 7127  Symbol and/or name change 5135510 APPROVED