RNF222 (ring finger protein 222) - Rat Genome Database

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Gene: RNF222 (ring finger protein 222) Homo sapiens
Analyze
Symbol: RNF222
Name: ring finger protein 222
RGD ID: 2299989
HGNC Page HGNC:34517
Description: Predicted to enable metal ion binding activity. Predicted to be located in membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: RING finger protein LOC643904
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,390,702 - 8,397,827 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,390,702 - 8,397,827 (-)EnsemblGRCh38hg38GRCh38
GRCh37178,294,020 - 8,301,145 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,236,842 - 8,237,504 (-)NCBINCBI36Build 36hg18NCBI36
Celera178,324,826 - 8,331,947 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef178,188,565 - 8,195,686 (-)NCBIHuRef
CHM1_1178,302,890 - 8,310,012 (-)NCBICHM1_1
T2T-CHM13v2.0178,296,885 - 8,304,024 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:16344560   PMID:16625196   PMID:24457600  


Genomics

Comparative Map Data
RNF222
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,390,702 - 8,397,827 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,390,702 - 8,397,827 (-)EnsemblGRCh38hg38GRCh38
GRCh37178,294,020 - 8,301,145 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,236,842 - 8,237,504 (-)NCBINCBI36Build 36hg18NCBI36
Celera178,324,826 - 8,331,947 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef178,188,565 - 8,195,686 (-)NCBIHuRef
CHM1_1178,302,890 - 8,310,012 (-)NCBICHM1_1
T2T-CHM13v2.0178,296,885 - 8,304,024 (-)NCBIT2T-CHM13v2.0
Rnf222
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391168,772,947 - 68,786,605 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1168,779,379 - 68,786,603 (+)EnsemblGRCm39 Ensembl
GRCm381168,882,121 - 68,895,779 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1168,888,553 - 68,895,777 (+)EnsemblGRCm38mm10GRCm38
MGSCv371168,702,055 - 68,708,517 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361168,704,748 - 68,711,201 (+)NCBIMGSCv36mm8
Celera1175,833,832 - 75,840,297 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.16NCBI
Rnf222
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,090,219 - 54,102,161 (+)NCBIGRCr8
mRatBN7.21053,596,751 - 53,603,305 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1053,596,751 - 53,603,300 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,258,056 - 58,264,522 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01057,746,894 - 57,753,360 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,255,771 - 53,262,315 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,472,794 - 55,484,850 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,478,298 - 55,484,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,215,117 - 55,227,027 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,648,501 - 55,655,048 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11055,666,273 - 55,666,909 (+)NCBI
Celera1052,763,234 - 52,769,778 (+)NCBICelera
Cytogenetic Map10q24NCBI
Rnf222
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,505,014 - 8,511,750 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,505,014 - 8,511,750 (+)NCBIChiLan1.0ChiLan1.0
RNF222
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21965,358,740 - 65,368,564 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11770,165,293 - 70,174,452 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01743,261,111 - 43,268,394 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11747,994,282 - 48,001,372 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1747,998,613 - 47,999,275 (+)Ensemblpanpan1.1panPan2
RNF222
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1533,164,444 - 33,172,178 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl533,166,234 - 33,166,839 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha533,300,323 - 33,308,040 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0533,267,627 - 33,275,353 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl533,269,415 - 33,270,020 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1533,234,745 - 33,242,458 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0533,190,013 - 33,197,733 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0533,370,038 - 33,377,771 (-)NCBIUU_Cfam_GSD_1.0
Rnf222
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560248,139,833 - 48,146,834 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,615,862 - 1,616,497 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,615,862 - 1,616,497 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF222
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,560,810 - 53,561,445 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,559,061 - 53,566,689 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21256,034,791 - 56,042,831 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNF222
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,746,387 - 7,749,267 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,747,921 - 7,748,580 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605913,629,379 - 13,637,261 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf222
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,961,315 - 10,961,962 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,959,468 - 10,966,329 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RNF222
14 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17p13.1(chr17:7750804-10112969)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052460]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052460]|See cases [RCV000052460] Chr17:7750804..10112969 [GRCh38]
Chr17:7654122..10016286 [GRCh37]
Chr17:7594847..9957011 [NCBI36]
Chr17:17p13.1		 pathogenic
GRCh38/hg38 17p13.2-13.1(chr17:6307904-8842949)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053407]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053407]|See cases [RCV000053407] Chr17:6307904..8842949 [GRCh38]
Chr17:6211224..8746266 [GRCh37]
Chr17:6151948..8686991 [NCBI36]
Chr17:17p13.2-13.1		 pathogenic
GRCh38/hg38 17p13.1(chr17:7478195-8435524)x1 copy number loss See cases [RCV000053426] Chr17:7478195..8435524 [GRCh38]
Chr17:7381514..8338842 [GRCh37]
Chr17:7322238..8279567 [NCBI36]
Chr17:17p13.1		 pathogenic
GRCh38/hg38 17p13.2-12(chr17:5732953-12095349)x3 copy number gain See cases [RCV000134851] Chr17:5732953..12095349 [GRCh38]
Chr17:5636273..11998666 [GRCh37]
Chr17:5576997..11939391 [NCBI36]
Chr17:17p13.2-12		 pathogenic
GRCh38/hg38 17p13.3-12(chr17:162016-12343901)x3 copy number gain See cases [RCV000138531] Chr17:162016..12343901 [GRCh38]
Chr17:45835..12247218 [GRCh37]
Chr17:11807..12187943 [NCBI36]
Chr17:17p13.3-12		 pathogenic
GRCh38/hg38 17p13.1(chr17:7967712-8490279)x3 copy number gain See cases [RCV000141063] Chr17:7967712..8490279 [GRCh38]
Chr17:7871030..8393597 [GRCh37]
Chr17:7811755..8334322 [NCBI36]
Chr17:17p13.1		 uncertain significance
GRCh38/hg38 17p13.3-12(chr17:150732-14764202)x3 copy number gain See cases [RCV000142236] Chr17:150732..14764202 [GRCh38]
Chr17:525..14667519 [GRCh37]
Chr17:525..14608244 [NCBI36]
Chr17:17p13.3-12		 pathogenic
GRCh37/hg19 17p13.1(chr17:7966164-8338622)x3 copy number gain See cases [RCV000447606] Chr17:7966164..8338622 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:7241916-8692213)x1 copy number loss See cases [RCV000445992] Chr17:7241916..8692213 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh37/hg19 17p13.1(chr17:7929776-9995862)x3 copy number gain See cases [RCV000447853] Chr17:7929776..9995862 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.1(chr17:7431013-9868179)x3 copy number gain See cases [RCV000511388] Chr17:7431013..9868179 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.3-12(chr17:525-15027737)x3 copy number gain See cases [RCV000511786] Chr17:525..15027737 [GRCh37]
Chr17:17p13.3-12		 pathogenic
NM_001146684.3(RNF222):c.26G>A (p.Ser9Asn) single nucleotide variant Inborn genetic diseases [RCV003272348] Chr17:8393436 [GRCh38]
Chr17:8296754 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001146684.3(RNF222):c.331G>A (p.Ala111Thr) single nucleotide variant Inborn genetic diseases [RCV003273284] Chr17:8393131 [GRCh38]
Chr17:8296449 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-12(chr17:525-11186432)x3 copy number gain not provided [RCV000683866] Chr17:525..11186432 [GRCh37]
Chr17:17p13.3-12		 pathogenic
GRCh37/hg19 17p13.1(chr17:8219814-8676240)x3 copy number gain not provided [RCV000683885] Chr17:8219814..8676240 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.1(chr17:7676383-8350870)x3 copy number gain not provided [RCV000848522] Chr17:7676383..8350870 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:7241916-8692213) copy number loss not specified [RCV002052586] Chr17:7241916..8692213 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh37/hg19 17p13.1(chr17:7929776-9995862) copy number gain not specified [RCV002052588] Chr17:7929776..9995862 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001146684.3(RNF222):c.572C>G (p.Ser191Trp) single nucleotide variant Inborn genetic diseases [RCV002906292] Chr17:8392890 [GRCh38]
Chr17:8296208 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001146684.3(RNF222):c.433C>T (p.Arg145Trp) single nucleotide variant Inborn genetic diseases [RCV002882493] Chr17:8393029 [GRCh38]
Chr17:8296347 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001146684.3(RNF222):c.536T>C (p.Leu179Pro) single nucleotide variant Inborn genetic diseases [RCV002946101] Chr17:8392926 [GRCh38]
Chr17:8296244 [GRCh37]
Chr17:17p13.1		 likely benign
NM_001146684.3(RNF222):c.199G>A (p.Val67Ile) single nucleotide variant Inborn genetic diseases [RCV002998286] Chr17:8393263 [GRCh38]
Chr17:8296581 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001146684.3(RNF222):c.436G>C (p.Glu146Gln) single nucleotide variant Inborn genetic diseases [RCV002693814] Chr17:8393026 [GRCh38]
Chr17:8296344 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001146684.3(RNF222):c.362G>C (p.Gly121Ala) single nucleotide variant Inborn genetic diseases [RCV002764072] Chr17:8393100 [GRCh38]
Chr17:8296418 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001146684.3(RNF222):c.227G>A (p.Arg76His) single nucleotide variant Inborn genetic diseases [RCV002744815] Chr17:8393235 [GRCh38]
Chr17:8296553 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001146684.3(RNF222):c.260C>A (p.Thr87Lys) single nucleotide variant Inborn genetic diseases [RCV002764937] Chr17:8393202 [GRCh38]
Chr17:8296520 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001146684.3(RNF222):c.520C>T (p.Leu174Phe) single nucleotide variant Inborn genetic diseases [RCV002679976] Chr17:8392942 [GRCh38]
Chr17:8296260 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001146684.3(RNF222):c.248A>G (p.Lys83Arg) single nucleotide variant Inborn genetic diseases [RCV003173762] Chr17:8393214 [GRCh38]
Chr17:8296532 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_001146684.3(RNF222):c.31G>A (p.Gly11Ser) single nucleotide variant Inborn genetic diseases [RCV003264733] Chr17:8393431 [GRCh38]
Chr17:8296749 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh38/hg38 17p13.3-12(chr17:165730-11404096)x3 copy number gain Chromosome 17p13.3 duplication syndrome [RCV003327726] Chr17:165730..11404096 [GRCh38]
Chr17:17p13.3-12		 pathogenic
NM_001146684.3(RNF222):c.260C>T (p.Thr87Met) single nucleotide variant Inborn genetic diseases [RCV003368524] Chr17:8393202 [GRCh38]
Chr17:8296520 [GRCh37]
Chr17:17p13.1		 uncertain significance
Single allele duplication not provided [RCV003448671] Chr17:7709286..8297901 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.3-11.2(chr17:525-21510992)x3 copy number gain not specified [RCV003987215] Chr17:525..21510992 [GRCh37]
Chr17:17p13.3-11.2		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2696
Count of miRNA genes:829
Interacting mature miRNAs:987
Transcripts:ENST00000344001, ENST00000399398
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 3 14 621 1 1 65 1 14 383
Low 65 49 10 37 86 4 694 53 20 13 116 52 42 13 316 4 1
Below cutoff 1899 2247 1374 329 1433 220 2404 1456 3127 254 1171 1412 114 1 1067 1560 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000344001   ⟹   ENSP00000343799
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl178,390,704 - 8,393,489 (-)Ensembl
RefSeq Acc Id: ENST00000399398   ⟹   ENSP00000382330
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl178,390,702 - 8,397,827 (-)Ensembl
RefSeq Acc Id: NM_001146684   ⟹   NP_001140156
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,390,702 - 8,397,827 (-)NCBI
GRCh37178,294,022 - 8,301,144 (-)RGD
Celera178,324,826 - 8,331,947 (-)RGD
HuRef178,188,565 - 8,195,686 (-)RGD
CHM1_1178,302,890 - 8,310,012 (-)NCBI
T2T-CHM13v2.0178,296,885 - 8,304,009 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011523978   ⟹   XP_011522280
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,390,702 - 8,397,827 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011523980   ⟹   XP_011522282
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,390,702 - 8,397,827 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011523981   ⟹   XP_011522283
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,390,702 - 8,394,090 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054316915   ⟹   XP_054172890
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0178,296,885 - 8,304,024 (-)NCBI
RefSeq Acc Id: XM_054316916   ⟹   XP_054172891
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0178,296,885 - 8,304,024 (-)NCBI
RefSeq Acc Id: XM_054316917   ⟹   XP_054172892
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0178,296,885 - 8,304,024 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001140156   ⟸   NM_001146684
- UniProtKB: A6NCQ9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011522282   ⟸   XM_011523980
- Peptide Label: isoform X1
- UniProtKB: A6NCQ9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011522280   ⟸   XM_011523978
- Peptide Label: isoform X1
- UniProtKB: A6NCQ9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011522283   ⟸   XM_011523981
- Peptide Label: isoform X1
- UniProtKB: A6NCQ9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000382330   ⟸   ENST00000399398
RefSeq Acc Id: ENSP00000343799   ⟸   ENST00000344001
RefSeq Acc Id: XP_054172892   ⟸   XM_054316917
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054172890   ⟸   XM_054316915
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054172891   ⟸   XM_054316916
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A6NCQ9-F1-model_v2 AlphaFold A6NCQ9 1-220 view protein structure

Promoters
RGD ID:6794073
Promoter ID:HG_KWN:24964
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour
Transcripts:ENST00000344001
Position:
Human AssemblyChrPosition (strand)Source
Build 36178,237,661 - 8,238,161 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:34517 AgrOrtholog
COSMIC RNF222 COSMIC
Ensembl Genes ENSG00000189051 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000344001 ENTREZGENE
  ENST00000344001.3 UniProtKB/Swiss-Prot
  ENST00000399398 ENTREZGENE
  ENST00000399398.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot
GTEx ENSG00000189051 GTEx
HGNC ID HGNC:34517 ENTREZGENE
Human Proteome Map RNF222 Human Proteome Map
InterPro RNF222 UniProtKB/Swiss-Prot
  Znf-RING_LisH UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
  Znf_RING_CS UniProtKB/Swiss-Prot
KEGG Report hsa:643904 UniProtKB/Swiss-Prot
NCBI Gene 643904 ENTREZGENE
PANTHER PTHR47095 UniProtKB/Swiss-Prot
  RING FINGER PROTEIN 222 UniProtKB/Swiss-Prot
Pfam zf-RING_UBOX UniProtKB/Swiss-Prot
PharmGKB PA164725453 PharmGKB
PROSITE ZF_RING_1 UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
SMART RING UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
UniProt A6NCQ9 ENTREZGENE
  L8E767_HUMAN UniProtKB/TrEMBL
  RN222_HUMAN UniProtKB/Swiss-Prot