H2al1b (H2A histone family member L1B) - Rat Genome Database

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Gene: H2al1b (H2A histone family member L1B) Mus musculus
Analyze
No known orthologs.
Symbol: H2al1b
Name: H2A histone family member L1B
RGD ID: 2294784
MGI Page MGI
Description: Predicted to enable nucleosomal DNA binding activity. Predicted to be involved in heterochromatin organization. Predicted to be part of nucleosome. Predicted to be active in nucleus. Orthologous to human H2AL3 (H2A.L variant histone 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gm14474; histone cluster 2 family member; predicted gene 14474
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X11,168,671 - 11,169,160 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX11,168,671 - 11,169,165 (+)EnsemblGRCm39 Ensembl
GRCm38X11,302,432 - 11,302,921 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX11,302,432 - 11,302,926 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X10,879,615 - 10,880,055 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X10,879,518 - 10,880,055 (+)NCBIMGSCv36mm8
Cytogenetic MapXA1.1NCBI
cM MapX6.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleosome  (IBA)
nucleus  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
Additional References at PubMed
PMID:21873635  


Genomics

Variants

.
Variants in H2al1b
26 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302195Pbwg10_mpostnatal body weight growth 10 (mouse)Not determinedX126202173Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
1301551Spha1_msperm head anomaly 1 (mouse)Not determinedX1026622539921652Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001242947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BX294183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000189531   ⟹   ENSMUSP00000139582
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX11,168,671 - 11,169,165 (+)Ensembl
GRCm38.p6 EnsemblX11,302,432 - 11,302,926 (+)Ensembl
RefSeq Acc Id: NM_001242947   ⟹   NP_001229876
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X11,168,671 - 11,169,160 (+)NCBI
GRCm38X11,302,432 - 11,302,921 (+)ENTREZGENE
cM MapX ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001229876 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000139582
  ENSMUSP00000139582.2
Reference Protein Sequences
RefSeq Acc Id: NP_001229876   ⟸   NM_001242947
- UniProtKB: A0A087WP11 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000139582   ⟸   ENSMUST00000189531
Protein Domains
Histone H2A/H2B/H3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A087WP11-F1-model_v2 AlphaFold A0A087WP11 1-105 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3650131 AgrOrtholog
Ensembl Genes ENSMUSG00000101819 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000189531 ENTREZGENE
  ENSMUST00000189531.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.20.10 UniProtKB/TrEMBL
InterPro Histone-fold UniProtKB/TrEMBL
  Histone_core_D UniProtKB/TrEMBL
  Histone_H2A UniProtKB/TrEMBL
KEGG Report mmu:100042927 UniProtKB/TrEMBL
MGD MGI:3650131 ENTREZGENE
NCBI Gene 100042927 ENTREZGENE
PANTHER HISTONE H2A UniProtKB/TrEMBL
  PTHR23430 UniProtKB/TrEMBL
Pfam Histone UniProtKB/TrEMBL
PhenoGen H2al1b PhenoGen
PRINTS HISTONEH2A UniProtKB/TrEMBL
SMART H2A UniProtKB/TrEMBL
Superfamily-SCOP SSF47113 UniProtKB/TrEMBL
UniProt A0A087WP11 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-09-27 H2al1b  H2A histone family member L1B  Gm14474  predicted gene 14474  Symbol and/or name change 5135510 APPROVED