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Gene: GAGE2C (G antigen 2C) Homo sapiens
Symbol: GAGE2C
Name: G antigen 2C
Description: This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 4.2; CT4.2; G antigen 2; G antigen 2A/2B; G antigen 2B; G antigen 2B/2C; GAGE-2; GAGE-2B; GAGE-2C; GAGE2; GAGE2A; GAGE2B; MGC120097; MGC96883; MGC96930; MGC96942
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X49,331,615 - 49,338,962 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X49,226,171 - 49,233,491 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X49,113,115 - 49,120,435 (+)NCBINCBI36hg18NCBI36
CeleraX53,437,864 - 53,440,319 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,815,722 - 46,831,871 (+)NCBIHuRef
CHM1_1X49,433,877 - 49,441,140 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
References - curated
References - uncurated


miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GAGE2C
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2293117
Created: 2008-05-09
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.