MIR744 (microRNA 744) - Rat Genome Database
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Gene: MIR744 (microRNA 744) Homo sapiens
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Symbol: MIR744
Name: microRNA 744
RGD ID: 2290242
HGNC Page HGNC
Description: Predicted to be involved in several processes, including SMAD protein signal transduction; cellular response to forskolin; and positive regulation of gene expression. Predicted to localize to RISC complex.
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: hsa-mir-744; mir-744; MIRN744
RGD Orthologs
Mouse
Pig
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1712,081,899 - 12,081,996 (+)EnsemblGRCh38hg38GRCh38
GRCh381712,081,899 - 12,081,996 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371711,985,216 - 11,985,313 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361711,925,940 - 11,926,037 (+)NCBINCBI36hg18NCBI36
Celera1712,015,760 - 12,015,857 (+)NCBI
Cytogenetic Map17p12NCBI
HuRef1711,885,973 - 11,886,070 (+)NCBIHuRef
CHM1_11711,994,325 - 11,994,422 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:16954537   PMID:17604727   PMID:21037258   PMID:21991303   PMID:23695020   PMID:25543521   PMID:25961434   PMID:26259828   PMID:26485754   PMID:26505678   PMID:26646931  
PMID:27261616   PMID:27533461   PMID:27533465   PMID:28107193   PMID:28766230   PMID:28791400   PMID:29899543   PMID:30392569   PMID:30542724   PMID:30628685   PMID:30664260   PMID:31211984  
PMID:31292221   PMID:31522607   PMID:31553714   PMID:31884801   PMID:32335029   PMID:32366870  


Genomics

Comparative Map Data
MIR744
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1712,081,899 - 12,081,996 (+)EnsemblGRCh38hg38GRCh38
GRCh381712,081,899 - 12,081,996 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371711,985,216 - 11,985,313 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361711,925,940 - 11,926,037 (+)NCBINCBI36hg18NCBI36
Celera1712,015,760 - 12,015,857 (+)NCBI
Cytogenetic Map17p12NCBI
HuRef1711,885,973 - 11,886,070 (+)NCBIHuRef
CHM1_11711,994,325 - 11,994,422 (+)NCBICHM1_1
Mir744
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391165,625,559 - 65,625,658 (-)NCBIGRCm39mm39
GRCm381165,734,733 - 65,734,832 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1165,734,733 - 65,734,832 (-)EnsemblGRCm38mm10GRCm38
MGSCv371165,548,235 - 65,548,334 (-)NCBIGRCm37mm9NCBIm37
Celera1172,669,661 - 72,669,760 (-)NCBICelera
Cytogenetic Map11B3NCBI
MIR744
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1256,464,848 - 56,464,927 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11256,464,848 - 56,464,927 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21259,358,203 - 59,358,282 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
AGPAT3hsa-miR-744-5pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248
IER5hsa-miR-744-5pTarbaseexternal_infoSequencingPOSITIVE
ARL15hsa-miR-744-5pMirtarbaseexternal_infoSequencingFunctional MTI (Weak)20371350
BUB3hsa-miR-744-3pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248

Predicted Targets
Summary Value
Count of predictions:69096
Count of gene targets:21805
Count of transcripts:56977
Interacting mature miRNAs:hsa-miR-744-3p, hsa-miR-744-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 1 1 4 1
Low 74 60 100 41 234 37 161 35 123 90 163 162 7 14 46 1
Below cutoff 101 78 87 26 80 20 123 65 183 42 79 89 10 38 61 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000578242
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1712,081,899 - 12,081,996 (+)Ensembl
RefSeq Acc Id: NR_030613
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381712,081,899 - 12,081,996 (+)NCBI
GRCh371711,985,216 - 11,985,313 (+)RGD
Celera1712,015,760 - 12,015,857 (+)RGD
HuRef1711,885,973 - 11,886,070 (+)RGD
CHM1_11711,994,325 - 11,994,422 (+)NCBI
Sequence:

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17p13.2-12(chr17:5732953-12095349)x3 copy number gain See cases [RCV000134851] Chr17:5732953..12095349 [GRCh38]
Chr17:5636273..11998666 [GRCh37]
Chr17:5576997..11939391 [NCBI36]
Chr17:17p13.2-12
pathogenic
GRCh38/hg38 17p13.3-12(chr17:162016-12343901)x3 copy number gain See cases [RCV000138531] Chr17:162016..12343901 [GRCh38]
Chr17:45835..12247218 [GRCh37]
Chr17:11807..12187943 [NCBI36]
Chr17:17p13.3-12
pathogenic
GRCh38/hg38 17p13.3-12(chr17:150732-14764202)x3 copy number gain See cases [RCV000142236] Chr17:150732..14764202 [GRCh38]
Chr17:525..14667519 [GRCh37]
Chr17:525..14608244 [NCBI36]
Chr17:17p13.3-12
pathogenic
GRCh38/hg38 17p12-11.2(chr17:10892259-17964282)x3 copy number gain See cases [RCV000052476] Chr17:10892259..17964282 [GRCh38]
Chr17:10795576..17867596 [GRCh37]
Chr17:10736301..17808321 [NCBI36]
Chr17:17p12-11.2
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:33658 AgrOrtholog
COSMIC MIR744 COSMIC
Ensembl Genes ENSG00000266297 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000578242 ENTREZGENE
GTEx ENSG00000266297 GTEx
HGNC ID HGNC:33658 ENTREZGENE
Human Proteome Map MIR744 Human Proteome Map
miRBase MI0005559 ENTREZGENE
NCBI Gene 100126313 ENTREZGENE
PharmGKB PA164722971 PharmGKB
RNAcentral URS00000EC1BE RNACentral
  URS00002ED61F RNACentral
  URS00005FAA14 RNACentral