MIR920 (microRNA 920) - Rat Genome Database

Name: MIR920
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: MIR920 (microRNA 920) Homo sapiens

Analyze

Symbol:

MIR920

Name:

microRNA 920

Description:

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Type:

ncrna

RefSeq Status:

PROVISIONAL

Also known as:

hsa-mir-920; MIRN920

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	24,212,421 - 24,212,495 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	12	24,365,355 - 24,365,429 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	24,256,621 - 24,256,695 (+)	NCBI	NCBI36		hg18	NCBI36
Celera	12	29,512,153 - 29,512,227 (+)	NCBI
Cytogenetic Map	12	p12.1	NCBI
HuRef	12	24,134,403 - 24,134,477 (+)	NCBI		HuRef
CHM1_1	12	24,330,426 - 24,330,500 (+)	NCBI		CHM1_1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation (Toggle Annotation Detail/Summary View)

Gene-Chemical Interaction Annotations

References - curated

References - uncurated

Genomics

miRNA Target Status

Expression

Sequence

Nucleotide Sequences

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 12p12.3-12.1(chr12:19265334-25482589)x1	copy number loss	See cases [RCV000135588]	Chr12:19265334..25482589 [GRCh38] Chr12:19418268..25635523 [GRCh37] Chr12:19309535..25526790 [NCBI36] Chr12:12p12.3-12.1	likely pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:121255-34603274)x3	copy number gain	See cases [RCV000136611]	Chr12:121255..34603274 [GRCh38] Chr12:282465..34756209 [GRCh37] Chr12:100682..34647476 [NCBI36] Chr12:12p13.33-11.1	pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:121271-34603261)x3	copy number gain	See cases [RCV000139052]	Chr12:121271..34603261 [GRCh38] Chr12:282465..34756196 [GRCh37] Chr12:100698..34647463 [NCBI36] Chr12:12p13.33-11.1	pathogenic
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3	copy number gain	See cases [RCV000139555]	Chr12:121271..133196807 [GRCh38] Chr12:282465..133773393 [GRCh37] Chr12:100698..132283466 [NCBI36] Chr12:12p13.33-q24.33	pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:54427-34608071)x4	copy number gain	See cases [RCV000139787]	Chr12:54427..34608071 [GRCh38] Chr12:282465..34761006 [GRCh37] Chr12:33854..34652273 [NCBI36] Chr12:12p13.33-11.1	pathogenic
GRCh38/hg38 12p12.1(chr12:23460257-24693739)x1	copy number loss	See cases [RCV000141828]	Chr12:23460257..24693739 [GRCh38] Chr12:23613191..24846673 [GRCh37] Chr12:23504458..24737940 [NCBI36] Chr12:12p12.1	likely pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:64620-34682902)x4	copy number gain	See cases [RCV000142149]	Chr12:64620..34682902 [GRCh38] Chr12:173786..34835837 [GRCh37] Chr12:44047..34727104 [NCBI36] Chr12:12p13.33-11.1	pathogenic
GRCh38/hg38 12p13.33-11.22(chr12:121055-28415184)x1	copy number loss	Global developmental delay [RCV000052776]\|See cases [RCV000052776]	Chr12:121055..28415184 [GRCh38] Chr12:282465..28568117 [GRCh37] Chr12:100482..28459384 [NCBI36] Chr12:12p13.33-11.22	pathogenic
GRCh38/hg38 12p12.3-11.23(chr12:19295848-27012560)x1	copy number loss	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052782]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052782]\|See cases [RCV000052782]	Chr12:19295848..27012560 [GRCh38] Chr12:19448782..27165493 [GRCh37] Chr12:19340049..27056760 [NCBI36] Chr12:12p12.3-11.23	pathogenic
GRCh38/hg38 12p12.1-11.21(chr12:21771052-32222232)x1	copy number loss	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052783]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052783]\|See cases [RCV000052783]	Chr12:21771052..32222232 [GRCh38] Chr12:21923986..32375166 [GRCh37] Chr12:21815253..32266433 [NCBI36] Chr12:12p12.1-11.21	pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:77187-34380176)x3	copy number gain	Global developmental delay [RCV000053660]\|Coarse facial features [RCV000053661]\|See cases [RCV000053660]	Chr12:77187..34380176 [GRCh38] Chr12:282465..34533111 [GRCh37] Chr12:56614..34424378 [NCBI36] Chr12:12p13.33-11.1	pathogenic
GRCh38/hg38 12p13.33-12.1(chr12:80412-25470329)x3	copy number gain	Corpus callosum agenesis [RCV000053662]\|See cases [RCV000053662]	Chr12:80412..25470329 [GRCh38] Chr12:282465..25623263 [GRCh37] Chr12:59839..25514530 [NCBI36] Chr12:12p13.33-12.1	pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:212976-33926913)x4	copy number gain	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053666]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053666]\|See cases [RCV000053666]	Chr12:212976..33926913 [GRCh38] Chr12:322142..34079848 [GRCh37] Chr12:192403..33971115 [NCBI36] Chr12:12p13.33-11.1	pathogenic
GRCh38/hg38 12p12.3-12.1(chr12:18252085-25696258)x3	copy number gain	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053670]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053670]\|See cases [RCV000053670]	Chr12:18252085..25696258 [GRCh38] Chr12:18405019..25849192 [GRCh37] Chr12:18296286..25740459 [NCBI36] Chr12:12p12.3-12.1	pathogenic

Additional Information

External Database Links

More on MIR920
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: hg19 hg38
	HGNC Report
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	2290235
Created:	2008-02-29
Species:	Homo sapiens
Last Modified:	2019-11-26
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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