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Gene: TTLL8 (tubulin tyrosine ligase like 8) Homo sapiens
Symbol: TTLL8
Name: tubulin tyrosine ligase like 8
Description: Predicted to have protein-glycine ligase activity, initiating. Predicted to be involved in protein polyglycylation. Predicted to localize to axoneme and microtubule cytoskeleton; INTERACTS WITH aflatoxin B1; benzo[e]pyrene; methapyrilene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: protein monoglycylase TTLL8; tubulin tyrosine ligase-like family member 8; tubulin tyrosine ligase-like family, member 8; tubulin--tyrosine ligase-like protein 8
Mus musculus (house mouse) : Ttll8 (tubulin tyrosine ligase-like family, member 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ttll8 (tubulin tyrosine ligase like 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttll8 (tubulin tyrosine ligase like 8)
Pan paniscus (bonobo/pygmy chimpanzee) : TTLL8 (tubulin tyrosine ligase like 8)
Canis lupus familiaris (dog) : TTLL8 (tubulin tyrosine ligase like 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttll8 (tubulin tyrosine ligase like 8)
Sus scrofa (pig) : TTLL8 (tubulin tyrosine ligase like 8)
Chlorocebus sabaeus (African green monkey) : TTLL8 (tubulin tyrosine ligase like 8)
Heterocephalus glaber (naked mole-rat) : Ttll8 (tubulin tyrosine ligase like 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2250,015,123 - 50,056,935 (-)EnsemblGRCh38hg38GRCh38
GRCh382250,018,575 - 50,058,227 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372250,466,026 - 50,496,636 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362248,795,679 - 48,835,182 (-)NCBINCBI36hg18NCBI36
Celera2234,329,184 - 34,368,139 (-)NCBI
Cytogenetic Map22q13.33NCBI
HuRef2233,363,855 - 33,394,447 (-)NCBIHuRef
CHM1_12250,415,898 - 50,455,656 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TTLL8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2290198
Created: 2008-02-29
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.