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Gene: Atp4b (ATPase H+/K+ transporting subunit beta) Rattus norvegicus
Symbol: Atp4b
Name: ATPase H+/K+ transporting subunit beta
RGD ID: 2178
Description: Predicted to contribute to sodium:potassium-exchanging ATPase activity. Involved in pH reduction; response to lipopolysaccharide; and response to organonitrogen compound. Localizes to membrane. Used to study obesity. Human ortholog(s) of this gene implicated in atrophic gastritis; autoimmune gastritis; and stomach cancer. Orthologous to human ATP4B (ATPase H+/K+ transporting subunit beta); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; esomeprazole pharmacokinetics pathway; INTERACTS WITH ammonium chloride; bisphenol A; copper atom.
Type: protein-coding
Also known as: ATPase H+/K+ transporting beta subunit; ATPase H+K+-transporting beta / (gastric HK-ATPase beta subunit) defined by SSR; ATPase, H+,K+-transporting, beta / (gastric H,K-ATPase beta subunit), defined by SSR; ATPase, H+,K+-transporting, beta / (gastric H,K-ATPase beta subunit), defined by SSR,; ATPase, H+/K+ exchanging, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide; gastric H(+)/K(+) ATPase subunit beta; potassium-transporting ATPase subunit beta; proton pump beta chain; S76401S1
Homo sapiens (human) : ATP4B (ATPase H+/K+ transporting subunit beta)  HGNC  Alliance
Mus musculus (house mouse) : Atp4b (ATPase, H+/K+ exchanging, beta polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp4b (ATPase H+/K+ transporting subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP4B (ATPase H+/K+ transporting subunit beta)
Canis lupus familiaris (dog) : ATP4B (ATPase H+/K+ transporting subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp4b (ATPase H+/K+ transporting subunit beta)
Sus scrofa (pig) : ATP4B (ATPase H+/K+ transporting subunit beta)
Chlorocebus sabaeus (African green monkey) : ATP4B (ATPase H+/K+ transporting subunit beta)
Heterocephalus glaber (naked mole-rat) : Atp4b (ATPase H+/K+ transporting subunit beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01681,136,218 - 81,145,131 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1681,136,218 - 81,145,131 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01680,624,778 - 80,633,691 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41681,000,154 - 81,009,067 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11681,000,418 - 81,009,332 (+)NCBI
Celera1673,951,353 - 73,960,266 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
RH 3.4 Map16743.6RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Atp4b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2178
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.