Itgb3bp (integrin subunit beta 3 binding protein) - Rat Genome Database

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Gene: Itgb3bp (integrin subunit beta 3 binding protein) Heterocephalus glaber
Analyze
Symbol: Itgb3bp
Name: integrin subunit beta 3 binding protein
RGD ID: 18936916
Description: INVOLVED IN negative regulation of epithelial cell apoptotic process (ortholog); positive regulation of epithelial cell proliferation (ortholog); ASSOCIATED WITH Craniosynostosis Syndrome, Autosomal Recessive (ortholog); endometriosis (ortholog); genetic disease (ortholog); FOUND IN inner kinetochore (ortholog); kinetochore (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: centromere protein R
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474230,639,358 - 30,691,265 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474230,638,885 - 30,694,362 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Itgb3bp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474230,639,358 - 30,691,265 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474230,638,885 - 30,694,362 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ITGB3BP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38163,440,770 - 63,529,187 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl163,440,770 - 63,593,721 (-)EnsemblGRCh38hg38GRCh38
GRCh37163,906,441 - 63,988,896 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,679,050 - 63,761,423 (-)NCBINCBI36Build 36hg18NCBI36
Build 34163,618,482 - 63,700,856NCBI
Celera162,196,117 - 62,278,760 (-)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef162,014,402 - 62,097,032 (-)NCBIHuRef
CHM1_1164,022,010 - 64,104,751 (-)NCBICHM1_1
T2T-CHM13v2.0163,316,450 - 63,404,983 (-)NCBIT2T-CHM13v2.0
Itgb3bp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39499,655,643 - 99,717,403 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl499,653,639 - 99,787,010 (-)EnsemblGRCm39 Ensembl
GRCm38499,767,406 - 99,829,215 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl499,765,402 - 99,929,813 (-)EnsemblGRCm38mm10GRCm38
MGSCv37499,432,093 - 99,495,809 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36499,257,420 - 99,321,136 (-)NCBIMGSCv36mm8
Celera498,141,678 - 98,205,369 (-)NCBICelera
Cytogenetic Map4C6NCBI
cM Map445.71NCBI
Itgb3bp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85119,575,657 - 119,640,974 (-)NCBIGRCr8
mRatBN7.25114,460,217 - 114,525,538 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5114,460,221 - 114,525,704 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5117,016,629 - 117,081,676 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05118,741,951 - 118,806,997 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05118,804,486 - 118,869,532 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05118,476,410 - 118,541,928 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5118,476,430 - 118,673,780 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05122,404,696 - 122,470,214 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45120,459,569 - 120,525,476 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15120,515,435 - 120,530,702 (-)NCBI
Celera5113,008,525 - 113,073,454 (-)NCBICelera
Cytogenetic Map5q33NCBI
Itgb3bp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542326,510,255 - 26,570,884 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542326,510,979 - 26,568,796 (+)NCBIChiLan1.0ChiLan1.0
ITGB3BP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21163,330,456 - 163,416,610 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11162,481,070 - 162,565,076 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0162,695,675 - 62,779,887 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1164,506,240 - 64,588,657 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl164,506,240 - 64,588,657 (-)Ensemblpanpan1.1panPan2
ITGB3BP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1546,645,858 - 46,716,170 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl546,681,412 - 46,701,509 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha546,706,463 - 46,776,413 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0546,826,086 - 46,896,586 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl546,826,005 - 46,896,481 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1546,787,686 - 46,857,614 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0546,734,200 - 46,804,216 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0546,991,568 - 47,062,207 (+)NCBIUU_Cfam_GSD_1.0
Itgb3bp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505876,724,663 - 76,776,392 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366921,038,790 - 1,091,660 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366921,040,894 - 1,091,741 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGB3BP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12069,564,456 - 69,638,157 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603347,822,548 - 47,897,119 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000024898   ⟹   ENSHGLP00000024676
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474230,639,358 - 30,691,265 (+)Ensembl
RefSeq Acc Id: XM_004841524   ⟹   XP_004841581
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474230,639,193 - 30,694,362 (+)NCBI
RefSeq Acc Id: XM_021255622   ⟹   XP_021111281
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474230,650,736 - 30,694,362 (+)NCBI
RefSeq Acc Id: XM_021255623   ⟹   XP_021111282
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474230,638,885 - 30,694,362 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004841581 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111281 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111282 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024676
GenBank Protein JAN99392 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021111282   ⟸   XM_021255623
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JVB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004841581   ⟸   XM_004841524
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JVB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111281   ⟸   XM_021255622
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JVB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000024676   ⟸   ENSHGLT00000024898


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017596 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000024898 ENTREZGENE
InterPro CENP-R UniProtKB/TrEMBL
NCBI Gene Itgb3bp ENTREZGENE
PANTHER CENTROMERE PROTEIN R UniProtKB/TrEMBL
  PTHR15581 UniProtKB/TrEMBL
Pfam CENP-R UniProtKB/TrEMBL
PIRSF NRIF3_coact_rcpt UniProtKB/TrEMBL
UniProt A0A0P6JVB9 ENTREZGENE, UniProtKB/TrEMBL