Loxhd1 (lipoxygenase homology PLAT domains 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Loxhd1 (lipoxygenase homology PLAT domains 1) Heterocephalus glaber
Analyze
Symbol: Loxhd1
Name: lipoxygenase homology PLAT domains 1 (Ensembl:lipoxygenase homology domains 1)
RGD ID: 18936441
Description: INVOLVED IN sensory perception of sound (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 77 (ortholog); Deafness (ortholog); FOUND IN stereocilium (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lipoxygenase homology domain-containing protein 1; lipoxygenase homology domains 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477810,106,975 - 10,282,085 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477810,106,009 - 10,282,085 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
stereocilium  (IEA)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Loxhd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477810,106,975 - 10,282,085 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477810,106,009 - 10,282,085 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LOXHD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381846,476,961 - 46,657,220 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1846,476,972 - 46,657,220 (-)EnsemblGRCh38hg38GRCh38
GRCh371844,056,924 - 44,237,183 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361842,343,528 - 42,435,624 (-)NCBINCBI36Build 36hg18NCBI36
Build 341842,343,527 - 42,435,624NCBI
Celera1840,864,351 - 41,044,583 (-)NCBICelera
Cytogenetic Map18q21.1NCBI
HuRef1840,914,566 - 41,094,608 (-)NCBIHuRef
CHM1_11843,983,947 - 44,163,994 (-)NCBICHM1_1
T2T-CHM13v2.01846,667,522 - 46,847,775 (-)NCBIT2T-CHM13v2.0
Loxhd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391877,369,354 - 77,530,628 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1877,369,654 - 77,530,626 (+)EnsemblGRCm39 Ensembl
GRCm381877,281,658 - 77,442,932 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1877,281,958 - 77,442,930 (+)EnsemblGRCm38mm10GRCm38
MGSCv371877,520,697 - 77,680,996 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361877,512,200 - 77,586,778 (+)NCBIMGSCv36mm8
Celera1878,460,582 - 78,625,896 (+)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1852.2NCBI
Loxhd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81873,093,142 - 73,245,784 (+)NCBIGRCr8
mRatBN7.21870,817,962 - 70,970,606 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1870,818,276 - 70,969,983 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1872,920,937 - 73,073,126 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01873,590,152 - 73,742,331 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01871,446,745 - 71,598,914 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01873,645,365 - 73,812,271 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1873,645,907 - 73,812,271 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01873,325,886 - 73,492,157 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41874,297,027 - 74,399,097 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11874,319,056 - 74,472,488 (+)NCBI
Celera1869,340,110 - 69,490,847 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
Loxhd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540231,985,583 - 32,144,040 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540231,985,616 - 32,144,040 (-)NCBIChiLan1.0ChiLan1.0
LOXHD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21763,898,106 - 64,079,259 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11849,590,703 - 49,771,860 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01839,756,531 - 39,936,317 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11843,290,361 - 43,469,923 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1843,290,579 - 43,469,921 (-)Ensemblpanpan1.1panPan2
LOXHD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1744,662,800 - 44,828,405 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl744,663,182 - 44,826,858 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha744,145,778 - 44,310,709 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0744,615,788 - 44,781,462 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1744,315,651 - 44,480,579 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0744,369,642 - 44,534,212 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0744,653,348 - 44,817,946 (+)NCBIUU_Cfam_GSD_1.0
LOC101976443
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494440,992,760 - 41,083,909 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936517271,909 - 409,691 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936517271,909 - 409,818 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOXHD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl196,080,824 - 96,276,992 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1196,080,751 - 96,287,034 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOXHD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11834,247,584 - 34,431,038 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1834,249,250 - 34,430,532 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660508,619,822 - 8,802,681 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000008701   ⟹   ENSHGLP00000008610
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477810,106,975 - 10,282,085 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000008702   ⟹   ENSHGLP00000008611
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477810,171,304 - 10,237,022 (-)Ensembl
RefSeq Acc Id: XM_004855091   ⟹   XP_004855148
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477810,106,009 - 10,282,085 (-)NCBI
RefSeq Acc Id: XM_004855092   ⟹   XP_004855149
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477810,106,009 - 10,282,085 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004855148 (Get FASTA)   NCBI Sequence Viewer  
  XP_004855149 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000008610
Reference Protein Sequences
RefSeq Acc Id: XP_004855149   ⟸   XM_004855092
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004855148   ⟸   XM_004855091
- Peptide Label: isoform X1
- UniProtKB: G5BL85 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000008611   ⟸   ENSHGLT00000008702
RefSeq Acc Id: ENSHGLP00000008610   ⟸   ENSHGLT00000008701


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006211 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000008701 ENTREZGENE
Gene3D-CATH Catalase core domain UniProtKB/TrEMBL
  PLAT/LH2 domain UniProtKB/TrEMBL
InterPro PLAT/LH2_dom UniProtKB/TrEMBL
  PLAT/LH2_dom_sf UniProtKB/TrEMBL
NCBI Gene Loxhd1 ENTREZGENE
PANTHER LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PROTEIN CBG12474 UniProtKB/TrEMBL
Pfam PLAT UniProtKB/TrEMBL
PROSITE PLAT UniProtKB/TrEMBL
SMART LH2 UniProtKB/TrEMBL
Superfamily-SCOP Lipase/lipooxygenase domain (PLAT/LH2 domain) UniProtKB/TrEMBL
UniProt G5BL85 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-16 Loxhd1  lipoxygenase homology PLAT domains 1  Loxhd1  lipoxygenase homology domains 1  Symbol and/or name change 5135510 APPROVED