LOC101700701 (cytochrome P450 11B1, mitochondrial) - Rat Genome Database

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Gene: LOC101700701 (cytochrome P450 11B1, mitochondrial) Heterocephalus glaber
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Symbol: LOC101700701
Name: cytochrome P450 11B1, mitochondrial
RGD ID: 18935880
Description: ENCODES a protein that exhibits corticosterone 18-monooxygenase activity (ortholog); steroid 11-beta-monooxygenase activity (ortholog); INVOLVED IN adrenal gland development (ortholog); aldosterone biosynthetic process (ortholog); C21-steroid hormone biosynthetic process (ortholog); PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH adrenal cortical adenoma (ortholog); autism spectrum disorder (ortholog); corticosterone methyloxidase deficiency 1 (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473513,701,382 - 13,708,750 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC101700701
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473513,701,382 - 13,708,750 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CYP11B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388142,910,559 - 142,917,843 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8142,910,559 - 142,917,843 (-)EnsemblGRCh38hg38GRCh38
GRCh378143,991,975 - 143,999,259 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368143,988,977 - 143,996,261 (-)NCBINCBI36Build 36hg18NCBI36
Build 348143,988,976 - 143,996,261NCBI
Celera8140,301,421 - 140,308,694 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8139,244,244 - 139,251,515 (-)NCBIHuRef
CHM1_18144,032,236 - 144,039,525 (-)NCBICHM1_1
T2T-CHM13v2.08144,053,900 - 144,061,172 (-)NCBIT2T-CHM13v2.0
Cyp11b2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391574,722,467 - 74,728,080 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1574,722,859 - 74,728,167 (-)EnsemblGRCm39 Ensembl
GRCm381574,850,618 - 74,856,231 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1574,851,010 - 74,856,318 (-)EnsemblGRCm38mm10GRCm38
MGSCv371574,681,440 - 74,686,748 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361574,678,294 - 74,683,480 (-)NCBIMGSCv36mm8
Celera1576,357,529 - 76,362,843 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.29NCBI
Cyp11b3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87108,689,319 - 108,694,808 (-)NCBIGRCr8
mRatBN7.27106,808,559 - 106,814,048 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7106,808,559 - 106,814,048 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7108,534,544 - 108,540,024 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07110,758,218 - 110,763,690 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07110,704,151 - 110,709,631 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07116,155,928 - 116,161,781 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,156,219 - 116,255,167 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,059,008 - 116,064,497 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,013,335 - 113,018,824 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17113,047,564 - 113,053,054 (-)NCBI
Celera7103,180,975 - 103,186,464 (-)NCBICelera
Cytogenetic Map7q34NCBI
CYP11B2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27160,346,798 - 160,354,193 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18135,873,004 - 135,880,399 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08139,622,632 - 139,630,014 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18142,666,534 - 142,672,575 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8142,666,534 - 142,672,575 (-)Ensemblpanpan1.1panPan2
CYP11B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11336,866,476 - 36,880,625 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1336,823,864 - 36,833,784 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,342,302 - 37,352,691 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11337,015,530 - 37,025,564 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,134,290 - 37,144,097 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01337,610,637 - 37,619,980 (+)NCBIUU_Cfam_GSD_1.0
CYP11B2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.141,365,725 - 1,373,138 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1


Expression


Sequence


RefSeq Acc Id: XM_004837858   ⟹   XP_004837915
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473513,701,382 - 13,708,750 (+)NCBI
RefSeq Acc Id: XM_021251256   ⟹   XP_021106915
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473513,701,382 - 13,708,750 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004837915 (Get FASTA)   NCBI Sequence Viewer  
  XP_021106915 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023419
RefSeq Acc Id: XP_004837915   ⟸   XM_004837858
- Peptide Label: isoform X1
- UniProtKB: G5AWE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106915   ⟸   XM_021251256
- Peptide Label: isoform X2
- UniProtKB: G5AWE1 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016698 ENTREZGENE
Ensembl Transcript ENSHGLT00000023636 ENTREZGENE
Gene3D-CATH Cytochrome P450 UniProtKB/TrEMBL
InterPro Cyt_P450 UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/TrEMBL
NCBI Gene LOC101700701 ENTREZGENE
PANTHER CYTOCHROME P450 11B2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR24279 UniProtKB/TrEMBL
Pfam p450 UniProtKB/TrEMBL
PRINTS EP450I UniProtKB/TrEMBL
  P450 UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/TrEMBL
Superfamily-SCOP Cytochrome P450 UniProtKB/TrEMBL
UniProt G5AWE0 ENTREZGENE, UniProtKB/TrEMBL
  G5AWE1 ENTREZGENE, UniProtKB/TrEMBL