P2ry6 (pyrimidinergic receptor P2Y6)

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Gene: P2ry6 (pyrimidinergic receptor P2Y6) Heterocephalus glaber

Analyze

Symbol:

P2ry6

Name:

pyrimidinergic receptor P2Y6

RGD ID:

18935472

Description:

ENCODES a protein that exhibits G protein-coupled ADP receptor activity (ortholog); G protein-coupled UDP receptor activity (ortholog); G protein-coupled UTP receptor activity (ortholog); INVOLVED IN cellular response to organic cyclic compound (ortholog); cellular response to prostaglandin E stimulus (ortholog); cellular response to purine-containing compound (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

P2Y purinoceptor 6

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Alliance Genes

More Info

more info ...

Latest Assembly:

HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly

Position:

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624817	3,648,829 - 3,672,051 (-)	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to organic cyclic compound (ISO)

cellular response to prostaglandin E stimulus (ISO)

cellular response to purine-containing compound (ISO)

cellular response to pyrimidine ribonucleotide (ISO)

phagocytosis (ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (ISO)

positive regulation of inositol trisphosphate biosynthetic process (ISO)

positive regulation of smooth muscle cell migration (ISO)

positive regulation of vascular associated smooth muscle cell proliferation (ISO)

transepithelial chloride transport (ISO)

Cellular Component

apical plasma membrane (ISO)

basolateral plasma membrane (ISO)

Molecular Function

G protein-coupled ADP receptor activity (ISO)

G protein-coupled UDP receptor activity (ISO)

G protein-coupled UTP receptor activity (ISO)

protein binding (ISO)

References

Genomics

Comparative Map Data

P2ry6
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624817	3,648,829 - 3,672,051 (-)	NCBI

P2RY6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	11	73,264,505 - 73,298,625 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p13 Ensembl	11	73,264,505 - 73,298,617 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	11	73,264,503 - 73,298,625 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	11	72,975,550 - 73,009,670 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	72,653,218 - 72,687,312 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	11	72,658,586 - 72,686,497	NCBI
Celera	11	70,280,653 - 70,314,752 (+)	NCBI
Cytogenetic Map	11	q13.4	NCBI
HuRef	11	69,270,867 - 69,304,972 (+)	NCBI		HuRef
CHM1_1	11	72,859,110 - 72,893,227 (+)	NCBI		CHM1_1

P2ry6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	100,586,837 - 100,628,528 (-)	NCBI	GRCm39		mm39
GRCm38	7	100,937,630 - 100,975,498 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	100,937,630 - 100,974,649 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	108,086,148 - 108,112,880 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	7	100,811,721 - 100,838,449 (-)	NCBI			mm8
Celera	7	101,288,708 - 101,316,203 (-)	NCBI		Celera
Cytogenetic Map	7	E2	NCBI

P2ry6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	1	165,972,439 - 166,008,348 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	165,972,440 - 165,997,751 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	172,169,438 - 172,204,831 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	158,381,127 - 158,406,783 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	158,460,144 - 158,485,800 (-)	NCBI
Celera	1	153,376,657 - 153,401,528 (-)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

P2ry6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	18,177,406 - 18,215,428 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	18,177,406 - 18,215,428 (-)	NCBI	ChiLan1.0	ChiLan1.0

P2RY6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	11	71,562,990 - 71,595,540 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	71,594,250 - 71,595,236 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	11	68,341,722 - 68,375,923 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

P2RY6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	21	24,929,771 - 24,930,757 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	21	24,929,502 - 24,966,857 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

P2ry6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936498	2,468,020 - 2,501,344 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

P2RY6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	7,726,631 - 7,759,721 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	7,708,452 - 7,759,721 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	8,538,019 - 8,554,097 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

P2RY6
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	1	64,541,221 - 64,542,207 (+)	Ensembl
ChlSab1.1	1	64,508,959 - 64,543,302 (+)	NCBI

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_004863270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_004863272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AHKG01079122	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

XM_004863270 ⟹ XP_004863327

RefSeq Status:

Type:

CODING

Position:

Molerat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624817	3,648,829 - 3,672,051 (-)	NCBI

RefSeq Acc Id:

XM_004863272 ⟹ XP_004863329

RefSeq Status:

Type:

CODING

Position:

Molerat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624817	3,648,829 - 3,653,517 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_004863327	(Get FASTA)	NCBI Sequence Viewer
	XP_004863329	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_004863327 ⟸ XM_004863270

RefSeq Acc Id:

XP_004863329 ⟸ XM_004863272

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	P2ry6	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)