Hrh3 (histamine receptor H3) - Rat Genome Database

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Gene: Hrh3 (histamine receptor H3) Heterocephalus glaber
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Symbol: Hrh3
Name: histamine receptor H3
RGD ID: 18934901
Description: ENCODES a protein that exhibits amine binding (ortholog); heterocyclic compound binding (ortholog); organic cyclic compound binding (ortholog); INVOLVED IN cAMP metabolic process (ortholog); cognition (ortholog); drinking behavior (ortholog); ASSOCIATED WITH amnestic disorder (ortholog); Experimental Seizures (ortholog); gastric ulcer (ortholog); FOUND IN dendrite (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histamine H3 receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474128,080,965 - 28,085,428 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474128,080,957 - 28,086,312 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
dendrite  (IEA)
membrane  (IEA)
plasma membrane  (IEA)
synapse  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hrh3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474128,080,965 - 28,085,428 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474128,080,957 - 28,086,312 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HRH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382062,214,960 - 62,220,278 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2062,214,960 - 62,220,278 (-)EnsemblGRCh38hg38GRCh38
GRCh372060,790,016 - 60,795,334 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362060,223,421 - 60,228,718 (-)NCBINCBI36Build 36hg18NCBI36
Build 342060,223,421 - 60,228,707NCBI
Celera2057,525,154 - 57,530,460 (-)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2057,566,507 - 57,570,202 (-)NCBIHuRef
CHM1_12060,690,583 - 60,695,889 (-)NCBICHM1_1
T2T-CHM13v2.02064,006,090 - 64,011,408 (-)NCBIT2T-CHM13v2.0
Hrh3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392179,741,258 - 179,746,264 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2179,741,258 - 179,746,281 (-)EnsemblGRCm39 Ensembl
GRCm382180,099,465 - 180,104,484 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2180,099,465 - 180,104,488 (-)EnsemblGRCm38mm10GRCm38
MGSCv372179,834,178 - 179,838,927 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362180,028,881 - 180,033,632 (-)NCBIMGSCv36mm8
Celera2184,181,575 - 184,186,324 (-)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2102.62NCBI
Hrh3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83187,569,174 - 187,575,263 (-)NCBIGRCr8
mRatBN7.23167,191,551 - 167,196,642 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3167,191,558 - 167,196,642 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3171,568,751 - 171,573,827 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03180,527,834 - 180,532,910 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03177,192,527 - 177,197,612 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03175,474,310 - 175,479,395 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3175,473,078 - 175,479,395 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03181,639,287 - 181,644,372 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43169,154,980 - 169,160,064 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13169,061,015 - 169,066,100 (-)NCBI
Celera3165,383,487 - 165,388,550 (+)NCBICelera
Cytogenetic Map3q43NCBI
Hrh3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555281,819,247 - 1,826,707 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555281,819,247 - 1,826,707 (+)NCBIChiLan1.0ChiLan1.0
HRH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22167,996,962 - 68,002,333 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12067,990,084 - 67,995,449 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02058,581,228 - 58,586,585 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12059,900,919 - 59,905,858 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2059,901,327 - 59,909,901 (-)Ensemblpanpan1.1panPan2
HRH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12446,239,883 - 46,243,123 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2445,476,507 - 45,480,947 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02447,095,982 - 47,100,422 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2447,096,070 - 47,100,764 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12446,197,405 - 46,201,844 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02446,320,612 - 46,325,047 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02447,074,908 - 47,079,348 (-)NCBIUU_Cfam_GSD_1.0
Hrh3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640194,408,461 - 194,412,309 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365149,862,523 - 9,873,159 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365149,862,104 - 9,865,614 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HRH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1761,622,938 - 61,627,278 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11761,622,865 - 61,627,278 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HRH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.122,019,878 - 2,025,218 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl22,020,286 - 2,025,202 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605049,967,430 - 49,972,751 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000024552   ⟹   ENSHGLP00000024332
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474128,080,965 - 28,085,428 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000024553   ⟹   ENSHGLP00000024333
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474128,081,275 - 28,085,428 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000024554   ⟹   ENSHGLP00000024334
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474128,081,445 - 28,085,428 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000024555   ⟹   ENSHGLP00000024335
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474128,082,017 - 28,085,428 (-)Ensembl
RefSeq Acc Id: XM_004841001   ⟹   XP_004841058
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474128,080,957 - 28,085,436 (-)NCBI
RefSeq Acc Id: XM_013070861   ⟹   XP_012926315
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474128,080,957 - 28,086,312 (-)NCBI
RefSeq Acc Id: XM_021255209   ⟹   XP_021110868
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474128,080,957 - 28,085,436 (-)NCBI
RefSeq Acc Id: XM_021255210   ⟹   XP_021110869
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474128,080,957 - 28,085,436 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004841058 (Get FASTA)   NCBI Sequence Viewer  
  XP_012926315 (Get FASTA)   NCBI Sequence Viewer  
  XP_021110868 (Get FASTA)   NCBI Sequence Viewer  
  XP_021110869 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024332
RefSeq Acc Id: XP_012926315   ⟸   XM_013070861
- Peptide Label: isoform X4
- UniProtKB: G5BDW9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110868   ⟸   XM_021255209
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021110869   ⟸   XM_021255210
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004841058   ⟸   XM_004841001
- Peptide Label: isoform X1
- UniProtKB: G5BDW9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000024333   ⟸   ENSHGLT00000024553
Ensembl Acc Id: ENSHGLP00000024334   ⟸   ENSHGLT00000024554
Ensembl Acc Id: ENSHGLP00000024332   ⟸   ENSHGLT00000024552
Ensembl Acc Id: ENSHGLP00000024335   ⟸   ENSHGLT00000024555


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017343 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000024552 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Histamine_H3_rcpt UniProtKB/TrEMBL
NCBI Gene Hrh3 ENTREZGENE
PANTHER 5-HYDROXYTRYPTAMINE RECEPTOR UniProtKB/TrEMBL
  HISTAMINE H3 RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  HISTAMINEH3R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0AAX6P0T6_HETGA UniProtKB/TrEMBL
  A0AAX6QTC6_HETGA UniProtKB/TrEMBL
  A0AAX6SPT0_HETGA UniProtKB/TrEMBL
  A0AAX6SQD3_HETGA UniProtKB/TrEMBL
  G5BDW9 ENTREZGENE, UniProtKB/TrEMBL