Mfsd2a (MFSD2 lysolipid transporter A, lysophospholipid) - Rat Genome Database

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Gene: Mfsd2a (MFSD2 lysolipid transporter A, lysophospholipid) Heterocephalus glaber
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Symbol: Mfsd2a
Name: MFSD2 lysolipid transporter A, lysophospholipid (Ensembl:major facilitator superfamily domain containing 2A)
RGD ID: 18934802
Description: ENCODES a protein that exhibits fatty acid transmembrane transporter activity (ortholog); long-chain fatty acid transporter activity (ortholog); lysophosphatidylcholine flippase activity (ortholog); INVOLVED IN brain development (ortholog); cellular response to starvation (ortholog); cognition (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); cryptorchidism (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: major facilitator superfamily domain containing 2A; major facilitator superfamily domain-containing protein 2A; sodium-dependent lysophosphatidylcholine symporter 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476422,422,423 - 22,435,416 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476422,422,520 - 22,435,332 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Mfsd2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476422,422,423 - 22,435,416 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476422,422,520 - 22,435,332 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MFSD2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38139,955,145 - 39,969,956 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl139,955,112 - 39,969,968 (+)EnsemblGRCh38hg38GRCh38
GRCh37140,420,817 - 40,435,628 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36140,193,397 - 40,208,215 (+)NCBINCBI36Build 36hg18NCBI36
Celera138,702,422 - 38,717,260 (+)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef138,539,329 - 38,554,171 (+)NCBIHuRef
CHM1_1140,536,427 - 40,551,270 (+)NCBICHM1_1
T2T-CHM13v2.0139,824,591 - 39,839,402 (+)NCBIT2T-CHM13v2.0
Mfsd2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394122,840,643 - 122,855,844 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4122,840,643 - 122,854,981 (-)EnsemblGRCm39 Ensembl
GRCm384122,946,850 - 122,961,194 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4122,946,850 - 122,961,188 (-)EnsemblGRCm38mm10GRCm38
MGSCv374122,624,093 - 122,638,431 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364122,449,153 - 122,463,473 (-)NCBIMGSCv36mm8
Celera4121,276,713 - 121,291,009 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map457.34NCBI
Mfsd2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85140,510,933 - 140,525,828 (-)NCBIGRCr8
mRatBN7.25135,225,801 - 135,240,744 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5135,225,816 - 135,240,690 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5137,932,684 - 137,947,368 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05139,702,687 - 139,717,377 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05139,709,784 - 139,724,468 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05140,642,865 - 140,657,759 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5140,642,885 - 140,657,745 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05144,433,445 - 144,448,324 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45142,260,560 - 142,275,435 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15142,265,780 - 142,280,604 (-)NCBI
Celera5133,764,543 - 133,779,074 (-)NCBICelera
Cytogenetic Map5q36NCBI
Mfsd2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545217,430,219 - 17,443,830 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545217,430,850 - 17,443,830 (+)NCBIChiLan1.0ChiLan1.0
MFSD2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21186,853,107 - 186,867,856 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11185,990,715 - 186,005,462 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0139,244,438 - 39,259,156 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1140,569,706 - 40,584,438 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl140,569,706 - 40,584,438 (+)Ensemblpanpan1.1panPan2
MFSD2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1152,966,433 - 2,979,030 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl152,966,461 - 2,978,968 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha153,223,537 - 3,236,132 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0153,053,922 - 3,066,514 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl153,053,950 - 3,066,453 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1152,960,820 - 2,973,412 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0153,020,725 - 3,033,317 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0153,037,135 - 3,049,729 (-)NCBIUU_Cfam_GSD_1.0
Mfsd2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505855,966,002 - 55,978,559 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647421,790,747 - 21,803,360 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647421,790,807 - 21,803,336 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MFSD2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl695,738,969 - 95,753,245 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1695,738,961 - 95,753,245 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2688,931,112 - 88,945,386 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MFSD2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12092,926,217 - 92,941,191 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2092,926,067 - 92,941,159 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603323,896,232 - 23,911,104 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


RefSeq Acc Id: ENSHGLT00000015516   ⟹   ENSHGLP00000015357
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476422,422,423 - 22,435,416 (+)Ensembl
RefSeq Acc Id: XM_004851038   ⟹   XP_004851095
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476422,422,673 - 22,435,332 (+)NCBI
RefSeq Acc Id: XM_004851039   ⟹   XP_004851096
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476422,422,520 - 22,435,053 (+)NCBI
RefSeq Acc Id: XM_021263401   ⟹   XP_021119060
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476422,422,520 - 22,435,053 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004851095 (Get FASTA)   NCBI Sequence Viewer  
  XP_004851096 (Get FASTA)   NCBI Sequence Viewer  
  XP_021119060 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000015357
  ENSHGLP00100053591
GenBank Protein JAO01609 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004851096   ⟸   XM_004851039
- Peptide Label: isoform X2
- UniProtKB: G5C410 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119060   ⟸   XM_021263401
- Peptide Label: isoform X3
- UniProtKB: G5C410 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851095   ⟸   XM_004851038
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JFT8 (UniProtKB/TrEMBL),   G5C410 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000015357   ⟸   ENSHGLT00000015516


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010975 Ensembl, ENTREZGENE
  ENSHGLG00100012687 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000015516 ENTREZGENE
  ENSHGLT00100079041 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS_2 UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
KEGG Report hgl:101716851 UniProtKB/TrEMBL
NCBI Gene Mfsd2a ENTREZGENE
PANTHER PTHR11328 UniProtKB/TrEMBL
  SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1 UniProtKB/TrEMBL
Pfam MFS_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt A0A0P6JFT8 ENTREZGENE, UniProtKB/TrEMBL
  G5C410 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-10-18 Mfsd2a  MFSD2 lysolipid transporter A, lysophospholipid  Mfsd2a  major facilitator superfamily domain containing 2A  Symbol and/or name change 5135510 APPROVED