Itpk1 (inositol-tetrakisphosphate 1-kinase) - Rat Genome Database

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Gene: Itpk1 (inositol-tetrakisphosphate 1-kinase) Heterocephalus glaber
Analyze
Symbol: Itpk1
Name: inositol-tetrakisphosphate 1-kinase
RGD ID: 18934649
Description: ENCODES a protein that exhibits inositol tetrakisphosphate 6-kinase activity (ortholog); INVOLVED IN necroptotic process (ortholog); neural tube development (ortholog); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; ASSOCIATED WITH achondrogenesis type IA (ortholog); genetic disease (ortholog); Neoplasm Invasiveness (ortholog); FOUND IN apical plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247349,417,939 - 9,568,702 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247349,420,232 - 9,568,655 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Itpk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247349,417,939 - 9,568,702 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247349,420,232 - 9,568,655 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ITPK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381492,936,914 - 93,115,925 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1492,936,914 - 93,116,320 (-)EnsemblGRCh38hg38GRCh38
GRCh371493,403,259 - 93,582,270 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361492,475,960 - 92,651,980 (-)NCBINCBI36Build 36hg18NCBI36
Build 341492,475,959 - 92,651,980NCBI
Celera1473,457,398 - 73,636,400 (-)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1473,584,961 - 73,762,800 (-)NCBIHuRef
CHM1_11493,341,508 - 93,520,507 (-)NCBICHM1_1
T2T-CHM13v2.01487,168,906 - 87,347,917 (-)NCBIT2T-CHM13v2.0
Itpk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912102,534,842 - 102,671,128 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12102,534,841 - 102,671,189 (-)EnsemblGRCm39 Ensembl
GRCm3812102,568,583 - 102,704,869 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12102,568,582 - 102,704,930 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712103,806,793 - 103,943,079 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612102,969,633 - 103,105,919 (-)NCBIMGSCv36mm8
Celera12103,782,829 - 103,919,411 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1251.69NCBI
Itpk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86127,475,589 - 127,609,320 (-)NCBIGRCr8
mRatBN7.26121,710,750 - 121,844,501 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6121,710,755 - 121,844,107 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6121,850,453 - 121,982,457 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06122,145,701 - 122,277,708 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06121,482,099 - 121,614,034 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06126,448,920 - 126,582,188 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6126,450,139 - 126,582,134 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06135,660,943 - 135,790,645 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46126,837,135 - 126,969,350 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6119,200,722 - 119,330,748 (-)NCBICelera
Cytogenetic Map6q32NCBI
Itpk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543815,107,891 - 15,257,740 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543815,107,992 - 15,257,730 (-)NCBIChiLan1.0ChiLan1.0
ITPK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21594,098,055 - 94,275,927 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11493,314,561 - 93,491,649 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01473,573,020 - 73,750,109 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11492,909,785 - 93,087,773 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1492,909,785 - 93,087,773 (-)Ensemblpanpan1.1panPan2
ITPK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.181,976,089 - 2,136,228 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl81,977,740 - 2,136,339 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha81,979,707 - 2,159,693 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.082,012,020 - 2,191,809 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.181,947,975 - 2,127,830 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.081,898,042 - 2,078,021 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.082,025,376 - 2,205,114 (-)NCBIUU_Cfam_GSD_1.0
Itpk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864012,402,818 - 12,536,055 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936733930,972 - 1,064,229 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936733930,986 - 1,064,223 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITPK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7114,361,968 - 114,520,793 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17114,361,976 - 114,520,805 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27120,970,535 - 121,053,191 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITPK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12470,680,791 - 70,860,132 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2470,679,303 - 70,859,587 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605357,929,735 - 58,110,383 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000009142   ⟹   ENSHGLP00000009045
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247349,417,939 - 9,568,702 (-)Ensembl
RefSeq Acc Id: XM_004837032   ⟹   XP_004837089
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247349,420,232 - 9,568,655 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004837089 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000009045
  ENSHGLP00100008467
GenBank Protein JAN99212 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004837089   ⟸   XM_004837032
- UniProtKB: A0A0P6J9E1 (UniProtKB/TrEMBL),   G5B2Y0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000009045   ⟸   ENSHGLT00000009142


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006496 Ensembl, ENTREZGENE
  ENSHGLG00100006300 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000009142 ENTREZGENE
  ENSHGLT00100008567 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1490.220 UniProtKB/TrEMBL
  3.40.50.11370 UniProtKB/TrEMBL
InterPro ATP-grasp UniProtKB/TrEMBL
  Inositol_tetrakis-P_1-kinase UniProtKB/TrEMBL
  InsP(3)kin_ATP-grasp UniProtKB/TrEMBL
  ITPK1_N UniProtKB/TrEMBL
KEGG Report hgl:101700462 UniProtKB/TrEMBL
NCBI Gene Itpk1 ENTREZGENE
PANTHER INOSITOL-TETRAKISPHOSPHATE 1-KINASE UniProtKB/TrEMBL
  PTHR14217 UniProtKB/TrEMBL
Pfam Ins134_P3_kin UniProtKB/TrEMBL
  Ins134_P3_kin_N UniProtKB/TrEMBL
PIRSF ITPK UniProtKB/TrEMBL
PROSITE ATP_GRASP UniProtKB/TrEMBL
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/TrEMBL
UniProt A0A0P6J9E1 ENTREZGENE, UniProtKB/TrEMBL
  G5B2Y0 ENTREZGENE, UniProtKB/TrEMBL