Atp1b3 (ATPase Na+/K+ transporting subunit beta 3) - Rat Genome Database

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Gene: Atp1b3 (ATPase Na+/K+ transporting subunit beta 3) Heterocephalus glaber
Analyze
Symbol: Atp1b3
Name: ATPase Na+/K+ transporting subunit beta 3
RGD ID: 18934408
Description: ENCODES a protein that exhibits ATPase binding (ortholog); P-type sodium:potassium-exchanging transporter activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN membrane repolarization (ortholog); metal ion transport (ortholog); positive regulation of ATP-dependent activity (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; FOUND IN caveola (ortholog); cytoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium/potassium-transporting ATPase subunit beta-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473018,510,844 - 18,544,836 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473018,510,840 - 18,544,528 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
alfentanil pharmacodynamics pathway  (ISO)
amiloride pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
bendroflumethiazide pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bumetanide pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
chlorothiazide pharmacodynamics pathway  (ISO)
chlorthalidone pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
cystinuria pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
eplerenone pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
etacrynic acid pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
furosemide pharmacodynamics pathway  (ISO)
Hartnup disease pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrochlorothiazide pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydroflumethiazide pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
iminoglycinuria pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
lactose degradation pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
lysinuric protein intolerance pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
metolazone pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
spironolactone pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
torasemide pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)
trehalose degradation pathway  (ISO)
triamterene pharmacodynamics pathway  (ISO)
trichlormethiazide pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Atp1b3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473018,510,844 - 18,544,836 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473018,510,840 - 18,544,528 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ATP1B3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383141,876,643 - 141,926,549 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3141,876,124 - 141,926,549 (+)EnsemblGRCh38hg38GRCh38
GRCh373141,595,485 - 141,645,391 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363143,078,160 - 143,128,072 (+)NCBINCBI36Build 36hg18NCBI36
Build 343143,078,167 - 143,128,080NCBI
Celera3140,019,481 - 140,069,148 (+)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3138,968,275 - 139,018,182 (+)NCBIHuRef
CHM1_13141,558,509 - 141,608,405 (+)NCBICHM1_1
T2T-CHM13v2.03144,623,941 - 144,673,839 (+)NCBIT2T-CHM13v2.0
Atp1b3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39996,214,708 - 96,246,368 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl996,214,708 - 96,246,495 (-)EnsemblGRCm39 Ensembl
GRCm38996,332,655 - 96,364,431 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl996,332,655 - 96,364,442 (-)EnsemblGRCm38mm10GRCm38
MGSCv37996,233,092 - 96,264,718 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36996,142,025 - 96,173,651 (-)NCBIMGSCv36mm8
Celera995,886,766 - 95,920,080 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map950.31NCBI
Atp1b3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88105,789,824 - 105,821,151 (-)NCBIGRCr8
mRatBN7.2896,910,265 - 96,941,592 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl856,357,316 - 56,358,259 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl896,910,309 - 96,941,598 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8102,575,419 - 102,606,805 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08100,774,668 - 100,806,054 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0898,613,628 - 98,645,015 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08104,190,032 - 104,221,342 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8104,190,032 - 104,221,342 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08103,638,324 - 103,669,634 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48101,405,877 - 101,437,757 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18101,425,331 - 101,457,212 (-)NCBI
Celera896,353,742 - 96,384,785 (-)NCBICelera
Cytogenetic Map8q31NCBI
Atp1b3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555083,859,399 - 3,875,276 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555083,848,745 - 3,875,992 (-)NCBIChiLan1.0ChiLan1.0
ATP1B3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22139,780,084 - 139,831,746 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13139,784,817 - 139,836,609 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03138,903,371 - 138,954,915 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13146,500,493 - 146,550,164 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3146,500,493 - 146,550,164 (+)Ensemblpanpan1.1panPan2
ATP1B3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12337,684,507 - 37,727,535 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2337,684,506 - 37,726,746 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2337,675,590 - 37,719,488 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02338,214,455 - 38,258,634 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2338,214,096 - 38,258,581 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12337,897,059 - 37,940,955 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02337,974,038 - 38,017,944 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02338,217,485 - 38,261,376 (+)NCBIUU_Cfam_GSD_1.0
Atp1b3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560276,881,663 - 76,901,102 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365403,621,656 - 3,640,885 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP1B3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11382,680,442 - 82,727,052 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21390,496,250 - 90,523,579 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ATP1B3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11548,691,224 - 48,742,336 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1548,690,667 - 48,742,385 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604121,627,404 - 21,678,499 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000017995   ⟹   ENSHGLP00000017819
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473018,510,844 - 18,544,836 (+)Ensembl
RefSeq Acc Id: XM_004834365   ⟹   XP_004834422
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473018,510,841 - 18,544,528 (+)NCBI
RefSeq Acc Id: XM_004834366   ⟹   XP_004834423
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473018,510,840 - 18,544,528 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004834422 (Get FASTA)   NCBI Sequence Viewer  
  XP_004834423 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017819
  ENSHGLP00100013831
GenBank Protein JAN98430 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004834423   ⟸   XM_004834366
- Peptide Label: isoform X2
- UniProtKB: G5AZ60 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004834422   ⟸   XM_004834365
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J4J7 (UniProtKB/TrEMBL),   G5AZ60 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000017819   ⟸   ENSHGLT00000017995


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012755 Ensembl, ENTREZGENE
  ENSHGLG00100010230 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000017995 ENTREZGENE
  ENSHGLT00100013986 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1660 UniProtKB/TrEMBL
InterPro Na/K_ATPase_sub_beta UniProtKB/TrEMBL
  Na/K_ATPase_sub_beta_sf UniProtKB/TrEMBL
KEGG Report hgl:101697891 UniProtKB/TrEMBL
NCBI Gene Atp1b3 ENTREZGENE
PANTHER PTHR11523 UniProtKB/TrEMBL
  SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3 UniProtKB/TrEMBL
Pfam Na_K-ATPase UniProtKB/TrEMBL
PROSITE ATPASE_NA_K_BETA_1 UniProtKB/TrEMBL
UniProt A0A0P6J4J7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NPV2_HETGA UniProtKB/TrEMBL
  G5AZ60 ENTREZGENE, UniProtKB/TrEMBL