Lzts3 (leucine zipper tumor suppressor family member 3) - Rat Genome Database

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Gene: Lzts3 (leucine zipper tumor suppressor family member 3) Heterocephalus glaber
Analyze
Symbol: Lzts3
Name: leucine zipper tumor suppressor family member 3
RGD ID: 18934262
Description: ENCODES a protein that exhibits obsolete protein self-association (ortholog); PDZ domain binding (ortholog); INVOLVED IN protein homooligomerization (ortholog); regulation of postsynapse assembly (ortholog); ASSOCIATED WITH Huntington's disease-like 1 (ortholog); Inosine Triphosphatase Deficiency (ortholog); pantothenate kinase-associated neurodegeneration (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine zipper putative tumor suppressor 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,268,869 - 4,281,653 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,271,584 - 4,282,082 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Lzts3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,268,869 - 4,281,653 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,271,584 - 4,282,082 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LZTS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,162,617 - 3,173,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl203,162,617 - 3,173,549 (-)EnsemblGRCh38hg38GRCh38
GRCh37203,143,263 - 3,154,195 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,091,273 - 3,097,207 (-)NCBINCBI36Build 36hg18NCBI36
Build 34203,091,272 - 3,097,207NCBI
Celera203,205,231 - 3,211,165 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef203,091,031 - 3,097,003 (-)NCBIHuRef
CHM1_1203,143,306 - 3,149,240 (-)NCBICHM1_1
T2T-CHM13v2.0203,193,522 - 3,204,462 (-)NCBIT2T-CHM13v2.0
Lzts3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,474,685 - 130,484,764 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,474,759 - 130,484,723 (-)EnsemblGRCm39 Ensembl
GRCm382130,632,765 - 130,642,866 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2130,632,839 - 130,642,803 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,458,575 - 130,468,539 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,324,213 - 130,334,285 (-)NCBIMGSCv36mm8
Celera2131,857,390 - 131,867,607 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.24NCBI
Lzts3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,303,378 - 138,313,645 (-)NCBIGRCr8
mRatBN7.23117,850,286 - 117,861,132 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3117,851,702 - 117,860,081 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3121,744,582 - 121,754,799 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,342,131 - 130,352,346 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,000,716 - 128,010,934 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,174,444 - 123,185,649 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,175,860 - 123,179,644 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,672,572 - 129,683,734 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,264,579 - 118,268,363 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,170,151 - 118,173,254 (-)NCBI
Celera3116,662,570 - 116,666,354 (-)NCBICelera
Cytogenetic Map3q36NCBI
Lzts3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541514,065,338 - 14,072,617 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541514,065,338 - 14,075,718 (-)NCBIChiLan1.0ChiLan1.0
LZTS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,129,943 - 4,140,949 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1204,126,762 - 4,137,774 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0203,248,955 - 3,259,932 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1203,011,611 - 3,022,582 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl203,011,611 - 3,022,573 (-)Ensemblpanpan1.1panPan2
LZTS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12418,111,188 - 18,122,246 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2418,117,723 - 18,120,428 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,940,272 - 17,950,683 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02418,530,804 - 18,541,218 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2418,531,201 - 18,541,054 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12418,124,487 - 18,134,901 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02418,237,097 - 18,247,509 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,564,415 - 18,574,829 (+)NCBIUU_Cfam_GSD_1.0
Lzts3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640167,106,923 - 167,116,423 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648515,538,337 - 15,548,148 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648515,538,302 - 15,547,778 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LZTS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,508,706 - 32,518,522 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,507,512 - 32,518,524 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,877,505 - 36,888,515 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LZTS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1233,835,361 - 33,845,948 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl233,835,012 - 33,839,895 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607110,667,679 - 10,679,140 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000023117   ⟹   ENSHGLP00000022903
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247414,268,869 - 4,281,653 (-)Ensembl
RefSeq Acc Id: XM_004840703   ⟹   XP_004840760
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247414,271,584 - 4,281,065 (-)NCBI
RefSeq Acc Id: XM_004840704   ⟹   XP_004840761
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247414,271,584 - 4,282,082 (-)NCBI
RefSeq Acc Id: XM_004840705   ⟹   XP_004840762
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247414,271,584 - 4,281,065 (-)NCBI
RefSeq Acc Id: XM_004840707   ⟹   XP_004840764
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247414,271,584 - 4,276,709 (-)NCBI
RefSeq Acc Id: XM_004840708   ⟹   XP_004840765
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247414,271,584 - 4,276,709 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004840760 (Get FASTA)   NCBI Sequence Viewer  
  XP_004840761 (Get FASTA)   NCBI Sequence Viewer  
  XP_004840762 (Get FASTA)   NCBI Sequence Viewer  
  XP_004840764 (Get FASTA)   NCBI Sequence Viewer  
  XP_004840765 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB04294 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000022903
Reference Protein Sequences
RefSeq Acc Id: XP_004840761   ⟸   XM_004840704
- Peptide Label: isoform X1
- UniProtKB: G5B4T3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840762   ⟸   XM_004840705
- Peptide Label: isoform X2
- UniProtKB: G5B4T3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840760   ⟸   XM_004840703
- Peptide Label: isoform X1
- UniProtKB: G5B4T3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840765   ⟸   XM_004840708
- Peptide Label: isoform X3
- UniProtKB: G5B4T3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840764   ⟸   XM_004840707
- Peptide Label: isoform X3
- UniProtKB: G5B4T3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000022903   ⟸   ENSHGLT00000023117


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016337 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000023117 ENTREZGENE
InterPro LZTS UniProtKB/TrEMBL
NCBI Gene Lzts3 ENTREZGENE
PANTHER ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED UniProtKB/TrEMBL
  ZIPPER PUTATIVE TUMOR SUPPRESSOR 3-RELATED UniProtKB/TrEMBL
Pfam Fez1 UniProtKB/TrEMBL
UniProt G5B4T3 ENTREZGENE, UniProtKB/TrEMBL